 
                            Andrew Sharp
@drandrewsharp
Interested in stuff.
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PE session in the main arena at 07.30 this morning (40 mins from now). Come join us - will be presenting some new data on catheter treatment of High Risk/Massive PE #TCT2025
Mastering disaster at #TCT2025 - dealing with access site haemorrhage. Know your coronary and peripheral kit if you are aiming for endovascular bailout
 
                                            Most Updated Global Burden of Cardiovascular Disease now out in @JACCJournals 80% (!) of CV disease burden is attributable to modifiable RFs Top modifiable risks in 2023: ⚠️ High systolic BP ⚠️ Dietary risks ⚠️ High LDL cholesterol ⚠️ Air pollution 🔗 jacc.org/doi/10.1016/j.…
 
                                            Useful graphic: average age-of-onset of autoimmune disorders
 
                                            A large, rigorous study published in JAMA last year found no association between autism and #acetaminophen use in pregnancy after accounting for heritability. Read this new interview with the study’s senior author about the findings. #paracetamol ja.ma/42gRoLu
Early Bird Registration is NOW OPEN! 🚨 Join us in Cardiff, 14–16 April 2026, for the Cardiff Echocardiography Course, a three-day intensive program designed to take your echo skills from basic to advanced. 💰 Save £100 when you register by Monday, 2 February 2026 – no code…
Not sure there is a more noble thing on Earth than to rescue a Good Boy.
Thank you for giving him the life he deserves
Imagine living your life knowing a terrible disease was coming. Every month now we see developments that would have seemed like Science Fiction 20 years ago. The pace of change is accelerating.
Experimental gene therapy for #Huntington’s markedly slowed disease progression in key trial Data likely put Uniqure medicine on track to be first genetic treatment for the condition statnews.com/2025/09/24/hun… via @statnews
Not all intermediate-risk #PE is the same. Does this warrant different therapeutic approaches? @drandrewsharp explains at #PERT2025
 
                                             
                                             
                                            Despite closure of San Diego airport yesterday evening, PERT is busy at breakfast time. Impressive turnout. #pert2025
 
                                            In the STRIKE‐PE study, computer assisted vacuum thrombectomy for pulmonary embolism rapidly improved right heart function and symptoms, with a low rate of major adverse events. #AHAJournals @drandrewsharp ahajrnls.org/4pqBacx
 
                                            If you believe free speech is for you but not your political opponents, you're illiberal. If no contrary evidence could change your beliefs, you're a fundamentalist. If you believe the state should punish those with contrary views, you're a totalitarian. If you believe…
Provocative study from the RENOVATE trialists and Samsung Med Cntr suggesting use of intravascular imaging may eliminate long-term diffs between CABG & PCI. Not definitive absent a powered RCT, but should be enough to mandate IVI in these pts, esp with class I guidelines. Agree?
 
                                             
                                             
                                             
                                            Extraordinary numbers. I know the line for hypertension has shifted, but all these numbers suggest the epidemic of hypertension is out of control.
Trends in BP awareness and control in young adults over 2003 to 2023, using data from NHANES 🔗 academic.oup.com/ajh/article/38… 🔒 #Hypertension
The story of AAS use on the top of anticoagulant is finally end. everyone will be now very conscious to avoid this combination, as it is unfortunately still used. nejm.org/doi/full/10.10… #ESCCongress 2025
 
                                            Presented at #ESCCongress: In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therapy led to a lower seated systolic blood pressure than placebo at 12 weeks. Full trial results: nej.md/4my7xUZ…
 
                                            Presented at #ESCCongress: In patients with heart failure and reduced ejection fraction who were receiving guideline-directed medical therapy, digitoxin lowered the risk of death or hospitalization for heart failure as compared with placebo. Full DIGIT-HF phase 4 trial results:…
 
                                            📢 Breaking news! Late-breaking clinical trials and science at #TCT2025 have been revealed! Get a front row seat to the latest breakthroughs redefining patient care around the world. 🌎 ✅ Explore the full lineup now: ow.ly/SuUV50WN3Yn ✅ Secure your spot today!…
Pdf access currently free.
#WeekendReads from the #AdvanceAccess Renal Denervation: a State of the Art Review 🔗 academic.oup.com/ajh/advance-ar… 🔓
 
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