The icOS Lab
@icOSLab
The in crystallo Optical Spectroscopy (icOS) Lab. A joint platform of @IBS_Grenoble and @esrfsynchrotron. For colourful protein crystals, but not exclusively.
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Today the French collaborating groups @esrfsynchrotron are celebrating their thirtieth birthday with a ceremony, followed by scientific conferences 🎉. The @IBS_Grenoble is proud to celebrate 30 years of discoveries on D2AM, FIP and FIP2! #EPNcampus #StructuralBiology
This is the ESRF! Check out our new video and turn up the sound! #ThisistheESRF
My final @ccp4_mx study weekend as a PhD student 💎💎 @unisouthampton @sotonbiosci @SoCoBioDtp @DiamondLightSou @DougInstruments
Deeply saddened by the announcement of Prof Sine Larsen's passing. Former scientific director of the European Synchrotron Radiation Facility and president of the International Union of Crystallography, Sine had been Emeritus at the University of Copenhagen for several years. To…
It is with profound sadness that the ESRF mourns the passing of Professor Sine Larsen, former ESRF Director of Research for Life Sciences from 2003 to 2009, Professor Emerita at the University of Copenhagen and President of @IUCr from 2008 to 2014.
Découvrez le dernier numéro de la Lettre d’information de @IBS_Grenoble : urls.fr/8x0QV3
Tek Narsingh Malla et al.: Exploiting fourth-generation synchrotron radiation for enzyme and photoreceptor characterization #StructuralBiology #EnvironmentalChemistry #RadiationDamage ... #IUCr journals.iucr.org/paper?S2052252…
A great week away, really enjoyed giving a talk at the annual European conference on micro and nanoscale technologies for the biosciences in Montreux 🇨🇭🤓 followed by beamtime at BM07 🇫🇷 🫕 @esrfsynchrotron @icOSLab @SoCoBioDtp @DiamondLightSou @unisouthampton @sotonbiosci
Annular lipids: are they important, can they be replaced by non-native ones, can X-ray crystallography be used to study them, and finally, can we predict their position using AlphaFold? We tried to answer these questions in a recent paper in @FrontiersIn frontiersin.org/articles/10.33…
Sofia M. Kapetanaki et al.: Crystal structure of a bacterial photoactivated adenylate cyclase determined by serial femtosecond and serial synchrotron crystallography #ACDomain @UniOfSurrey @unihh @UniofOxford... #IUCr journals.iucr.org/paper?S2052252…
💎4-year PhD Position available in the Tews lab💎 @esrfsynchrotron and @unisouthampton @sotonbiosci - details and how to apply below: esrf.gestmax.eu/1809/1/phd-stu… findaphd.com/phds/project/s…
Retrouvez le dernier numéro de la Lettre d’information de @IBS_Grenoble : urlr.me/1ZVdp
Decoding mEos4b Day-Long Maturation and Engineering Fast Maturing Variants biorxiv.org/cgi/content/sh… #biorxiv_biophys
Running the practical on time-resolved crystallography of membrane proteins with the real sample - new light-driven sodium pump. This is definitely not the easiest option but we never pursue easy routes :) Totally worth it.
Third day of Practicals for the EMBO mPEPC3 course at EMBL Hamburg. Practical H. Time- resolved serial crystallography of membrane proteins in lipidic cubic phase 💠 Tutors : Kirill Kovalev @kirkovalev94 , David Von Stetten . P14 beam Sponsors: @SPTLabtech 💥 #EMBOPEPC
Crazy! The belly skin of live mice becomes transiently totally transparent if you rub it with tartrazine (the yellow dye of M&M's) science.org/doi/10.1126/sc…
The @IUCr is excited to announce that our longtime colleague, Louise Jones, who has managed @ActaCrystD and @ActaCrystF for many years, is taking on a new role! 🎉 Join us in congratulating Louise as she embarks on her new role as Head of Publishing Operations! #structuralbiology
Guillaume Gotthard et al.: Capturing the blue-light activated state of the Phot-LOV1 domain from Chlamydomonas reinhardtii using time-resolved serial synchrotron crystallography #BlueLightPhotoreceptors @eth @fu_berlin... #IUCr journals.iucr.org/paper?S2052252…
New paper out using X-ray driven reactivity with crystal spectroscopy @Diamond_MX
New paper out today with my PhD group and @sofia_et_al on @beamlineI24 using radiation damage to drive reactions and make molecular movies of structural and spectroscopic changes in a nitrite reductase at different pHs. doi.org/10.1016/j.jmb.…
Chia-Ying Huang et al.: Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryocooled crystals #MacromolecularCrystallography #RoomTemperature #LigandBinding ... #IUCr journals.iucr.org/paper?S2059798…
It’s a wrap! Today is the last day of the #EMBOTRSX course. Thanks to all the participants & speakers of this first EMBO course on Time-resolved macromolecular serial crystallography!
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