Siân Owen
@implosian
Microbiologist & phage phanatic! Enthusiastic explorer of microbial genomes. New PI at the Wadsworth Center. Currently obsessed with plasmid-dependent phages
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My lab is up and running and just needs enthusiastic phage biologists to populate it! Contact me or apply in the link if you are interested in a postdoc exploring plasmid-dependent phage biology in beautiful (and super affordable!) upstate New York🍎healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Care… 1/3
In case you needed a reason to go do a PhD with @APHage_ (other than the awesome science!)
Dr. @rabiafatima_ has "tPASsed". Too many feels. Thank you @implosian - sorry you couldn't make it for the presentation of the warhammer. I do get asked if I fear the graduates will use them against me... no! Not in public, anyway - they're all far too smart to get caught.
Get ready to dance, our paper – Phage DisCo: targeted discovery of bacteriophages by co-culture – has been pre-printed! 🪩 This has been a really fun project to work on with @implosian, @baym, @nquinoneso, Kesther and Carmen! biorxiv.org/content/10.110… 1/
Nature News piece on the hidden players of the gut microbiome (hint, they're phages, of course) “Our virome is hugely abundant and incredibly diverse, and we’ve looked at just a tiny percentage,” nature.com/articles/d4158…
Centers for Accelerating Phage (Bacteriophage) Therapy to Combat ESKAPE Pathogens (CAPT-CEP) (P01 Clinical Trial Not Allowed) dlvr.it/TFfcWx
🚨We're hiring a lab manager/research scientist! Come work with us @MSU_MicroImmuno at Montana State in beautiful Bozeman, MT We are a phage lab with diverse projects related to infectious disease, check us out here: patsecor.wixsite.com/mysite-1 apply here: jobs.montana.edu/postings/43723
doi.org/10.1016/j.mib.… @vivek_mutalik and @simroux_virus, this is your new graphical abstract:
Another step forward towards the post-plaque era! Great work helping to drag the phage field into the 21st Century. Many core methodologies we use to study phages haven't changed since they were invented almost 100 years ago
Finally, the preprint on my postdoc work from the past 3 years! With mentorship from @PaulTurnerLab and @EmonetLab, I developed a microscopic technique to measure attachment of viruses #phages to bacterial cells @YalePhage @QbioYale . biorxiv.org/content/10.110…
A great summary here of the challenges (and promises!) of studying non-canonical bacteriophages sciencedirect.com/science/articl…
Some partnerships are always fun!! Excited to share one such 🎉 product w @simroux_virus perspectives on our favorite “atypical” phages, for special issue to celebrate my former mentor Carol Gross @UCSF Tapping the treasure trove of atypical phages sciencedirect.com/science/articl…
Some partnerships are always fun!! Excited to share one such 🎉 product w @simroux_virus perspectives on our favorite “atypical” phages, for special issue to celebrate my former mentor Carol Gross @UCSF Tapping the treasure trove of atypical phages sciencedirect.com/science/articl…
Come see Amy at poster 174 & learn about how active prophages may change the trajectory & evolution of resistance to DNA damaging antibiotics 💊 ⚡️ #EMBOEvoEco
Fellow microbial immunity, mobile elements, and plasmid enthusiasts: the paper of our wonderful @BruriaSamuel on anti-defense genes in plasmids is now published in @Nature!!! Check out her thread below for highlights of our new results. 1/2
Meet The Shielded Plasmid🛡️🧬 Our new @Nature paper reveals how plasmids outsmart bacterial defenses during conjugation. It's all about being in the right place at the right time! The positioning of anti-defense genes boosts transfer efficiency🧵(1/7) nature.com/articles/s4158…
The Bartlett Lab is open for business at the Wadsworth Center! We study pathogens with "unusual" shapes (balls & corkscrews) to find vulnerabilities in their growth plans, and learn how bacterial shape impacts infection. We are hiring... join us! wadsworth.org/research/labor…
I'll be speaking about viral sociality at TEDxNewEngland on Wednesday 25th September, alongside a great lineup of other speakers. List of speakers & tickets here for anyone in the Boston area who might want to come: tedxnewengland.com/speakers #TEDxNE #SocialViruses #LoveVirology
Asher Leeks is pushing the boundaries of biomedical science with his innovative research on sociality in viruses🦠. To hear more about @AsherLeeks' approach to the future of viral research, attend our inaugural MIND+LIFE conference on 9/25. Info in bio. bit.ly/3zhSMSF
quantamagazine.org
Viruses Finally Reveal Their Complex Social Life | Quanta Magazine
New research has uncovered a social world of viruses full of cheating, cooperation and other intrigues, suggesting that viruses make sense only as members of a community.
A nice little highlight here in @NatureRevMicro by @cazares_adr and team on our work (+ from the Dechesne lab) rediscovering plasmid-dependent phages! A hundred or so are known (most isolated in the last few years!) and we've only scratched the surface 👀 nature.com/articles/s4157…
nature.com
Rediscovering plasmid-dependent phages
Nature Reviews Microbiology - This Genome Watch highlights how the revived interest in phages that target plasmid-carrying bacteria is expanding our knowledge of viral diversity, ecology and...
Multiplexed editing of phage genomes using retrons, now published at @NatureBiotech with lots of new bells and whistles. @ChloeFishman @katecrawdaddy @BhattaraiKline @Darshini_Poola @thekarenzhang @alex_gonzadel @matromont nature.com/articles/s4158…
The most beautiful exploration of a single phage's infection cycle that I have ever seen, incredible work @PlevkaLab !!
📢 Publication alert 📢 Congratulations to Lucie Valentová on her debut paper! 👏 *Structure and replication of 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 phage JDB30* recently published in The EMBO Journal! embopress.org/doi/full/10.10… #PhageResearch @CEITEC_Brno 🧵1/12
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