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We should ask @bogdienache and @kaulcsmc but here is my thinking: the trial was designed to show NI or LAAC with an upper bound of 1.3. IOW 30% worse. Since the lower bound was greater than 1.0, especially in the PP, we can say inferior as well as not noninferior If the CI…
This is my go to image for non-inferiority trial interpretation. (I can get the reference)
OCEAN journal club kickstarter: 1.) does failure to show superiority prove statistical non-inferiority? @drjohnm 2.) delta would be magnified or same with larger sample size? ARISTOTLE had 18k patient and warfarin event rate was 1.6 % 3.) what if apixaban was used? 4.) why…
All PPS9 lectures now available for free ! innovationsincrm.com/physiology-of-… #dontdisthehis @drpmoskal
Clinical onset of #ARVC after age 40 is usually less severe than early-onset disease, despite similar structural phenotype, & is associated with slower VTs & less VT storm, & appears to have a lower risk of progression to clinical #heartfailure. jacc.org/doi/10.1016/j.… #JACCCEP
In this @JICE_EP paper, we describe a rapid staining technique for assessment of pulsed field ablation lesions using an in vitro model. Referred to as the "modelo de la papa" at #LAHRS recently. link.springer.com/article/10.100…
Free read at @JICE_EP. There are many variables to consider for PFA. We examined one parameter (interpulse delay) and found that lesions were larger when the time between pulses was increased, regardless of total energy delivered. rdcu.be/eMG7u
#EHRAtopicweek on Sustainability in EP ✅ Reusing pacemakers and catheters is: 🩺 Safe — The recent Europace #EHRA_ESC Young EP survey found that over two-thirds (67.8%) of EPs have used reprocessed materials, most viewing them as safe and cost-effective. Published studies show…
Typical example of impact of BiF on QRS and repolarization. Note huge repo abnormalities in aVL and lead I with just LIF - clearly superior/anterior lateral wall i delayed = asynchronous; the same in inferior leads in LSF. Gone with BiF pacing
Happy to share access to Bifascicular pacing. BiF - really works, doing it for years. We have two fascicles for a reason... authors.elsevier.com/c/1m38S_ZByiTE… #dontdisthehis @drpmoskal @MargaridaPujol @DrRoderickTung
HCM-VTs were primarily three-dimensional re-entrant circuits with mid-myocardial involvement. Procedural success largely depended on the origin and extent of intramural involvement of VT re-entry. jacc.org/doi/10.1016/j.… #JACCCEP #cvHCM #epAblation
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