Josh Selfe
@joshsselfe
Neuroscience PhD student in the Akerman lab @OxNeuro. Intrigued by cortical circuits, all-optical techniques, sensory processing.
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Our paper "Memory reactivation generates new, adaptive behaviours that reach beyond direct experience" is now out nature.com/articles/s4159… ! With @AnnieBRawson, Jill O’Reilly and @HelenCBarron at @MRCBNDU @NDCNOxford 1/6
Amazing work by @gsgothard showing the developmental origins of the local inhibitory subnetworks of L2/3 pyramidal neurons. Give it a read!
🚨new preprint alert!🚨 very excited to share the story of my PhD work :) including: development of excitatory-inhibitory circuits, lineage labelling, in vivo patching and re-thinking blanket inhibition. biorxiv.org/content/10.110… See below for a quick summary! [1/17]
Super excited to share that this preprint is now out, the result of my MSc, and the first all-optical reporter of ionic driving force!
We are excited to present ORCHID, a new tool for all-Optical Reporting of Chloride Ion Driving force. bit.ly/45P6est In the brain, inhibition is mediated by Cl- permeable receptors. ORCHID can therefore be used to quantify the driving force across inhibitory receptors.
#zebrafish larvae imaged on home-built #lightsheet microscope assembled by a team of remarkable students Shawniya, Josh @joshsselfe, Stephan and Syed @SyedAdnanUddi11 with the guidance of incredible researchers @HagarLavian and @PortuguesLab at @CSHL @cshlcourses #neuroscience…
Thrilled to announce the release of our new preprint. Here we show how fast synaptic inhibition adapts to the level of cortical activity and demonstrate why this could be an important feature of how cortical networks process information. biorxiv.org/content/10.110…
I #choosethebluefish because our oceans are beautiful and so full of life and provide life to many. Thank you @MSCinAfrica for giving us a way to support sustainable seafood by looking for the blue fish! With your help future generations will have pristine oceans @WavescapeSA
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