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This month, I'm excited to introduce two new estimation methods in nlmixr2: Laplace (laplace) and adaptive Gaussian Quadrature (agq). lnkd.in/enZtJBXN
We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics. #nlmixr2 #rstats
New features in #nlmixr2 4.0, a #rstats package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-2…
The nlmixr2 team is thrilled to announce the release of nlmixr2 4.0! This major update introduces the WNL linear compartment solutions, replacing the previous ADVAN-based approach for improved accuracy, stability, and compatibility. blog.nlmixr2.org/blog/2025-07-1…
In this month blog I speak of some of the lesser known ggplot2 pharmacometric geoms that are included in rxode2: blog.nlmixr2.org/blog/2025-05-3…
Do you want to do pharmacometrics with neural network ODEs? You can use nlmixr2 as well as other tools. See this month's blog post: blog.nlmixr2.org/blog/2025-04-3…
In this month's blog, I discuss adding more observations to predictions to better visualize predictions vs observations. This is covered here: blog.nlmixr2.org/blog/2025-03-3…
blog.nlmixr2.org
nlmixr2 augmented plot | nlmixr2
nlmixr: open source nonlinear mixed-effects modeling for R.
In this month's blog, I talk about the ins an outs of plotting in rxode2: blog.nlmixr2.org/blog/2025-02-2…
In this month's blog post I talk about the current extensibility of the nlmixr2 ecosystem that allows expansion of code for linear models, named arguments in functions, and even neural network ODEs. blog.nlmixr2.org/blog/2025-01-2…
Happy Holidays! For this month's blog post, I am writing about the new mu2 and mu3 mu referencing that is available in nlmixr2 (actually nlmixr2est). I hope you have a good holiday season. blog.nlmixr2.org/blog/2024-12-1…
In this month's blog post, I discuss importing `monolix` to `rxode2` and `nlmixr2`. This is one of the new imports in `babelmixr2` that allows translating inbetween `NONMEM`, `Monolix` and `nlmixr2`. blog.nlmixr2.org/blog/2024-10-2…
blog.nlmixr2.org
monolix2rx | nlmixr2
nlmixr: open source nonlinear mixed-effects modeling for R.
nlmixr2 and rxode2 3.0 is out. It is a major release since there are some backward-incompatible changes. #nlmixr2 #rxode2 #rstats blog.nlmixr2.org/blog/2024-09-1…
blog.nlmixr2.org
nlmixr2 3.0 | nlmixr2
nlmixr: open source nonlinear mixed-effects modeling for R.
In this month's blog, I am mentioning a useful feature in `rxode2` and `pmxTools` that isn't mentioned too much -- calculating derived PK parameters. Thought raising awareness of this feature might help someone's analysis go smoother. blog.nlmixr2.org/blog/2024-08-0…
blog.nlmixr2.org
rxode2 calculating derived PK model parameters | nlmixr2
nlmixr: open source nonlinear mixed-effects modeling for R.
This month, in my blog I talk about about a new iteration of mu-referencing in nlmixr2, which I call mu2. blog.nlmixr2.org/blog/2024-07-0…
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