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Medicine Notes

@mednotes

Micro-repository of evidence-based clinical pearls.

Meta-analysis: no benefit from statin use on all-cause mortality in high-risk patients without CV disease http://bit.ly/b4QNKs


2009 updates on ACC/AHA guidelines for management of patients with STEMI http://content.onlinejacc.org/cgi/content/full/j.jacc.2009.10.015


Glucocorticoid use associated with increased risk of atrial fibrillation or flutter http://ow.ly/uqJn


Risk of hyperkalemia is small with use of ACEi in non-diabetic pts with hypertensive CKD http://bit.ly/SriRY


Chart of comparative antihypertensive drug trials http://bit.ly/TscTb


Early non-invasive ventilation after extubation of hypercapnic patients reduced risk of respiratory failure http://bit.ly/2PB0ob


Inhaled corticosteroids/LABA have mortality benefit in COPD. Tiotropium decreased exacerbations and withdrawals. http://bit.ly/13G6HO


Hypertonic NS and IV furosemide as alternatives to repeated paracenteses in refractory ascites http://bit.ly/syZdy


Meta-analysis: H. pylori eradication may reduce risk of gastric cancer http://bit.ly/T9jiD


Telmisartan did not prevent major renal outcomes in patients without microalbuminuria http://bit.ly/EinQq


FAMOUS trial: famotidine effective at preventing gastroduodenal ulcers and erosive esophagitis, while on low-dose ASA http://bit.ly/Ydobr


Early blockade of RAA slows retinopathy, but not nephropathy, in type 1 DM http://bit.ly/r5qxL


PPI therapy for 8 weeks induces rebound acid hypersecretion (RAHS) after withdrawal http://bit.ly/UlLo4


tPA has more benefit than harm up to 4.5 hours after onset of stroke symptoms http://bit.ly/13Bbdn


Prolonged low-dose corticosteroids beneficial in sever sepsis and septic shock http://bit.ly/747r4


No difference in efficacy between starting nicotine gum 4 weeks before or at quit date http://bit.ly/x9aTN


SSRI associated with modestly increased risk of GI bleed http://bit.ly/DavjF


Rosiglitazone associated with increased cardiovascular and all-cause mortality about diabetics on hemodialysis http://bit.ly/UUJR6


Welcome to the micro-repository of evidence-based clinical pearls.


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