Molquant
@molquant
Providing a biological framework to interpret genomics data. We generate novel therapeutic concepts, biological annotation, Dx signatures
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Wow. Wonder how many are positive by serology, i.e. had it but now recovered
Whoa, 147 (36%) out of 408 people tested positive for the #coronavirus at a large homeless shelter in Boston medrxiv.org/content/10.110… More interestingly, only ~1/6 showed symptoms among those tested positive, i.e. 1:5 for symptomatic vs asymptomatic. #COVID19
MA sewage viral PCR sampling estimates 115K infected v 446 official tally (3/25). Biobot acknowledges need for better per capita burden to nail estimates
How many people are infected with Covid-19? Sewage suggests that number is much higher than officially confirmed Read about our work published yesterday in medRxiv medium.com/@biobotanalyti…
I'm pretty tired of hearing how we scientists are supposed to be so productive now. Anyone with kids, elderly parents, lab members to worry about, stranded masters students, etc is too stressed and busy to be thinking big thoughts.
Post-exposure Prophylaxis for #COVID19 RCT open NOW! 1500 patients, Hydroxychloroquine vs placebo x 7d prophylaxis for Healthcare workers & household contact—Enroll online! meds shipped. PI: @boulware_dr clinicaltrials.gov/ct2/show/NCT04…
Another core pathway to modulate anti-tumor immunity: Hippo upregulates in T cells following CD3/28activation, acts to blunt anti-tumor CTLs journals.plos.org/plosbiology/ar…
Mike Snyder's team @StanfordMed developed molecular assays for aging, found #ageotypes. Powerful tools for testing anti-aging drugs #metformin #NAD nature.com/articles/s4159…
A rich dataset for triangulating synthetic lethal relationships in cancer
How many people are infected with Covid-19? Sewage suggests that number is much higher than officially confirmed Read about our work published yesterday in medRxiv medium.com/@biobotanalyti…
Congratulations Bill! His pioneering work on how cells sense oxygen provided key translational insight for the whole class of anti-angiogenesis cancer drugs cnn.com/2019/10/07/hea… @askmr
Network analysis hypothesizes that a number of other syndromes may also be modulated by epigenetic regulator drugs molquant.com/mq-blog/141982…
A glitch in the #epigenetic machinery causes #KabukiSyndrome. Learn about the chemical that could fix it.
This spectacular update to the cancer cell line encyclopedia provides essential new tools for translational work in cancer Thanks #CCLE team! nature.com/articles/s4158…
A privilege to be involved in @medisixtx a chance to impact T cell leukemias and lymphomas with CAR-T
Announcing our Series A funding, excited to have the opportunity to advance engineered cell therapy candidates for T cell malignancies dealstreetasia.com/stories/temase…
Armon Sharei @SQZBiotech: "we are a big believer in cells as therapeutics, better than any biologic or small molecule drug" #kiwithinsight
#kiwithinsight Amy Schumann @PolarisVC: key w @SQZBiotech was to convince Pharma partner that platform=therapeutic valuation @kochinstitute
#kiwithinsight @SQZBiotech serendipitously found squeezing cells enabled transduction @kochinstitute
Packed room at MIT’s #kiwithinsight ‘Cells in the City’. First up @SQZBiotech-developing tools for engineered cell therapy @kochinstitute
Gene therapy went through a ~20 year "winter" Then this in < 1 month @theLancet @NEJM @Nature
How do these lucky winners feel about our genome giveaway? "Nervous, excited and hopeful." #PMConf How would you feel if YOU won?
90% of the data in the world today has been created in the last two years alone | #BigData #IoT #RT bit.ly/2eMnRUz
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