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Well done @mulecc - your PhD work just published 😀nature.com/articles/s4146… I think we've only scratched the surface with this... H-NS allowing bacteria to direct their own evolution. Exciting times ahead...
Really excited to share this. A massive effort from @mulecc. We find that H-NS isn't just for gene silencing. All this time it's been busy capturing transposons, and inserting them into bound DNA. We think there are some big implications (1/4) biorxiv.org/content/10.110…
It was decided this would have been so not Rainbow Rhythms, so Peep Show will remain on Netflix.
hi @NetflixUK - the date warning badge has now been removed from Peep Show...can you confirm??
Excited to be doing some public engagement on Saturday at #CoCoMAD with the @Micro_Mad team! Please retweet and give us a follow to keep up with us over the weekend!
Very excited to be attending CoCoMad '23 @CotteridgePark this Saturday representing @IMIBirmingham 🧫Come and say hi to our team @pRobM91 @LillyCummins_ @freyaallen__ @roscobacterium @IzziePotterill
Catch me tomorrow at 12:00 at the Tuberculosis session talking about arabinose, phage, and and new GHs! @MicrobioSoc
Happy to announce my first, first author paper has been published in @OUPBioinfo. Our software, ChemGAPP, is a comprehensive analytic package for chemical genomics datasets. Check it out! Thanks to @BanzhafLab, @DaneshMoradi and @mgalactus. academic.oup.com/bioinformatics…
Latest paper from the lab, this one's the culmination of @lucas_walker92's PhD. He describes how two TFs can bind the same DNA site to regulate in V. cholerae. A simple mechanism for integration of quorum sensing and cAMP signalling in V. cholerae biorxiv.org/content/10.110…
@Hannahmayyd suffered that we don't have to! ChemGAPP is a very easy to use software package that people without sophisticated programming skills can analyse their chemical genomics data. Check it out.
ChemGAPP; A Package for Chemical Genomics Analysis and Phenotypic Profiling. biorxiv.org/content/10.110…
Went n won a poster prize at the Molecular Microbiology conference. So answered a couple of questions about it:
Next up for our interview with recent poster award winners at the 7th Molecular Microbiology conference is David Forrest @fozzz21 for their work ‘No non-sense: Prevention of non-specific transcription in Bacillus subtilis’ @GraingerLab Read it below 👇 onlinelibrary.wiley.com/do/10.1111/mmi…
Hypertension is a risk factor for neurodegeneration, and the choroid plexus may play a critical role in this process. But how can we use MRI to look at the damage non-invasively? Find out more today: doi.org/10.3389/fnmol.… #AD #MRI @CABI_UCL 🧠🧲
frontiersin.org
Frontiers | Investigating changes in blood-cerebrospinal fluid barrier function in a rat model of...
Chronic hypertension is a major risk factor for the development of neurodegenerative disease, yet the aetiology of hypertension-driven neurodegeneration rema...
🧵on the latest @DETECTIVE_AMR manuscript, which might be my favourite so far. It's about a quirky group of plasmids that accumulate and disseminate all sorts of accessory genes in Acinetobacter... 1/20 microbiologyresearch.org/content/journa…
I mis-clicked on one of my 150 open tabs and it happened to be a tab that's been open since 2019 with a paper that has a solution to the exact research problem I've been puzzling over today. This is the moment I've been waiting for and I've decided to never close any tabs again
First bit of work from my PhD looking at sequence type pangenomes and how they vary in structure and content - very pleased to have this out! 🥳 @alanmcn1 @DrRebeccaJHall @jomcinerney @chris_h_connor biorxiv.org/content/10.110…
E. coli packs a genome into cell 1/1000th of its length, duplicates it, and sends a copy to each daughter cell every twenty minutes. It's humiliating.
I learnt so much writing this review with @AnnSnaith @DrRebeccaJHall @alanmcn1 🤓 Spoiler: enhanced colonisation capabilities may be key for MDR clone evolution link.springer.com/article/10.100…
link.springer.com
The role of potentiating mutations in the evolution of pandemic Escherichia coli clones
European Journal of Clinical Microbiology & Infectious Diseases - The Escherichia coli species exhibits a vast array of variable lifestyles, including environmental, commensal, and pathogenic...
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