Martins S. Oderinde, Ph.D
@oderinde_m
Scientific Associate Director. Discovery Chemistry. Bristol Myers Squibb. Photocatalysis Expert. IAB Member of Angewandte Chemie.
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💊Accelerating Medicinal Chemistry💊: A C(sp3)-rich Fragment Toolbox for Redox-Neutral Cross-Coupling, appearing today in @chemrxiv: chemrxiv.org/engage/chemrxi… A great collaboration with brilliant drug hunters at BMS, Pfizer, and Biogen. Quick summary: A new toolbox of 15 sulfonyl…
Appearing today in @ScienceMagazine : science.org/doi/10.1126/sc…
Finally, RADICAL CROSS COUPLING without the exogenous REDOX. We disclose in @ChemRxiv (chemrxiv.org/engage/chemrxi…) a broadly general platform for achieving transformations that normally required excess metallic or chemical reducing agents or photochemical setups (and their…
Thank you very much! I must say though, it was a true team effort and wouldn't have been possible without @Jiawei1024, Jiayan, @JetTsien, Haoxiang, and our collaborators at BMS: Ben, David, @oderinde_m, Michael, and Max!
Triply Convergent Ni-Electrocatalytic Assembly of 1,1-diaryl Cyclobutanes, Azetidines, and Oxetanes, appearing today in @ChemRxiv :chemrxiv.org/engage/chemrxi… Increasingly complex, three-dimensional leads for drug discovery are testing the limits of modern organic synthesis. In…
I am thrilled to share our latest article in @ACSCatalysis where we unveiled the long awaited Diastereoselectivity Aspects of Ni-Metallaphotoredox Decarboxylative Cross-Coupling. Shout out to @rajchemraj #BMSChemistry. @ScienceAtBMS pubs.acs.org/doi/10.1021/ac…
Published today in @ScienceMagazine : science.org/doi/epdf/10.11…
Radical retrosynthesis strikes again. Primary RAEs can be mixed and matched with tertiary RAEs or olefins to make quaternary centers with a comical level of simplicity. Check out these applications. A fun collaboration with the great and powerful @Shenvi_Lab:…
Charges for color figures will no longer apply to manuscripts submitted after March 1, 2024. For your next submission, we invite you to check out the Viewpoint Article "Coloring Chemistry—How Mindful Color Choices Improve Chemical Communication" (doi.org/10.1002/anie.2…).
Published today in @J_A_C_S : pubs.acs.org/doi/full/10.10…
Chiral amino alcohols without the hassle, radically simplified appearing today in @ChemRxiv : chemrxiv.org/engage/chemrxi…
The most accessed papers in January where contributed, among others, by @RovisGroup, @EnamineLtd, @FJHGroup, @NevadoLab, @BaranLabReads @EngleLab, @oderinde_m, @TortosaLab, @isra_group See the list. ow.ly/GJRx50QCwnw
Published today in @angew_chem : onlinelibrary.wiley.com/doi/10.1002/an…
Degrade proteins, not your work schedule! A new method appearing today @ChemRxiv (chemrxiv.org/engage/chemrxi…) simplifies access to molecular glues (like PROTACS) to save medicinal chemists valuable time. One-step access from cheap commercial materials, a trivial experimental setup,…
Nickel-Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers (Phil S. Baran and co-workers) @BaranLabReads @EngleLab @g_laudadio @pneigenfind98 @Aron_Peter_ @mx_million @oderinde_m @MykhailiukChem #AngewandteVIP onlinelibrary.wiley.com/doi/10.1002/an…
The final version of this work has appeared today in @angew_chem : onlinelibrary.wiley.com/doi/epdf/10.10…
onlinelibrary.wiley.com
Nickel‐Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers**
There is a pressing need for general, direct couplings of tertiary alkyl fragments to (hetero)aryl halides. Herein a uniquely powerful and simple set of conditions with unparalleled generality and...
The updated version of this work has appeared today @ChemRxiv now with applications, scale-up, and mechanistic studies.
very happy to share this work with the community, but even happier about the amazing feedback from our colleagues @bmsnews who are already using this chemistry! Thanks a million to everyone who helped solving this puzzle with lightning speed. @Aron_Peter_ @oderinde_m @chemistte
Degrade proteins, not your work schedule! A new method appearing today @ChemRxiv (chemrxiv.org/engage/chemrxi…) simplifies access to molecular glues (like PROTACS) to save medicinal chemists valuable time. One-step access from cheap commercial materials, a trivial experimental setup,…
Degrade proteins, not your work schedule! A new method appearing today @ChemRxiv (chemrxiv.org/engage/chemrxi…) simplifies access to molecular glues (like PROTACS) to save medicinal chemists valuable time. One-step access from cheap commercial materials, a trivial experimental setup,…
Aminoalcohol block for organic LEGO!! Congrats Jiawei and the team!! @oderinde_m
Chiral amino alcohols without the hassle, radically simplified appearing today in @ChemRxiv : chemrxiv.org/engage/chemrxi…
Chiral amino alcohols without the hassle, radically simplified appearing today in @ChemRxiv : chemrxiv.org/engage/chemrxi…
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