Uday Bikkasani
@udaybb
Global CTO & Head of Technology Infrastructure at Novartis | #AI #Infrastructure #Data #Digital #IT #CTO | all opinions are personal
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In 2016 Geoffrey Hinton said “we should stop training radiologists now" since AI would soon be better at their jobs. He was right: models have outperformed radiologists on benchmarks for ~a decade. Yet radiology jobs are at record highs, with an average salary of $520k. Why?
Today Thinking Machines Lab is launching our research blog, Connectionism. Our first blog post is “Defeating Nondeterminism in LLM Inference” We believe that science is better when shared. Connectionism will cover topics as varied as our research is: from kernel numerics to…
We’ve (finally) added full support for MCP tools in ChatGPT. In developer mode, developers can create connectors and use them in chat for write actions (not just search/fetch). Update Jira tickets, trigger Zapier workflows, or combine connectors for complex automations.
Blockchain is moving past memes into institutions. Nasdaq’s tokenized stocks + BlackRock on-chain = real adoption flywheels + network effects 👉 reuters.com/business/finan…
The most important AI paper of 2025 might have just dropped. NVIDIA lays out a framework for Small Language Model agents that could outcompete LLMs. Here’s the full breakdown (and why it matters):
4 stages of training LLMs from scratch, clearly explained (with visuals):
We live in a brief and fascinating moment right now where there’s an insanely wide gap in productivity between two people just based on the tools they use and their specific workflows with AI. Just a few variables can be the difference between getting a 25% boost in productivity…
R.I.P paid courses... You can use any LLM like ChatGPT, Gemini, or Claude to build a custom course on any topic or subject. Here’s the mega prompt that we use to get world-class education for free:
Knowledge begets more knowledge, algorithms optimising other algorithms - we are using AlphaEvolve to optimise our AI ecosystem, the flywheels are spinning fast...
Introducing AlphaEvolve: a Gemini-powered coding agent for algorithm discovery. It’s able to: 🔘 Design faster matrix multiplication algorithms 🔘 Find new solutions to open math problems 🔘 Make data centers, chip design and AI training more efficient across @Google. 🧵
if you are not skillsmaxxing with o3 at minimum 3 hours every day, ngmi
o3 answers the question I ask all new models: "You have consumed more information than anyone in the history of the world and you've demonstrated an extraordinary ability to make connections among them. What are the most important non-consenus or even not-yet-hypothesized things…
The time is right for another massive unlock: Tokenisation of land assets. To understand how this can turbocharge the economy, see👇 Full video here: youtu.be/mHE3zaaVo9c?si…
Think about it—We'd never hand out $100 bills to strangers on the street, but we'll readily give an hour of our day to a pointless meeting or mindless scrolling. To live the lives we truly want, we must treat our time with the same (if not more) reverence as we do our money.
Overheard in Silicon Valley: "My biggest lesson from the last year is just, it’s all going to happen. All my childhood dreams of space colonies and brain interfaces and AI and robots. Everything is just… going to happen."
Daily walks help clear your mind
I read Google's paper about their quantum computer so you don't have to. They claim to have ran a quantum computation in 5 minutes that would take a normal computer 10^25 years. But what was that computation? Does it live up to the hype? I will break it down.🧵
New NotebookLM updates, rolling out today: 🎧Pass a note to the hosts – you can now click on ‘Customize’ in Audio Overviews to give additional instructions, such as focusing on a specific topic, source, or even adjusting the audience it’s optimized for. 🎧You can now minimize…
You can learn every single thing that made this possible.
I don't recall another time in CS history where a result like this is obvious to the point of banality to one group. And heretical to another.
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