#immunotherapy search results
🫁 CHIO3: Chemo + Durvalumab in N2 NSCLC. N2 clearance: 73.3% pCR: 30% R0: 93.3% 18-mo EFS: 60.6% Feasible, low toxicity, strong nodal downstaging in N2+ disease. 📖 Lung Cancer DOI 👉🏻 doi.org/10.1016/j.lung… #CánCare #NSCLC #Immunotherapy #lcsm
Seminar on Agilent Dako's PD-L1 Join us at Anderson Diagnostics and Labs, Chennai for an insightful session on the evolving role of PD-L1 testing in immunotherapy and precision oncology. Registration Link: docs.google.com/forms/d/e/1FAI… #PDL1 #CompanionDiagnostics #Immunotherapy
Phase 3 (PRESERVE-003): Gotistobart vs Docetaxel Post PD-(L)1 resistant sqNSCLC Early overlap → late separation (~6 months) HR 0.46 | Durable OS benefit 👉 Classic immunotherapy effect #MVOnco #NSCLC #Immunotherapy #LungCancer
'It's incredible, like science fiction': How a new wave of #immunotherapy is eliminating cancers After 100 years of development, treatments that bolster the body's immune system to fight #cancer are coming of age – and saving patients' By Jamie Ducharme bbc.com/future/article…
Allergy to peanuts affects approximately 2% of individuals in the US. 💡 This JAMA Insights discusses #PeanutAllergy, including diagnosis, introduction of peanuts to infant diet, and #immunotherapy options. ja.ma/4bnHMCf
One hidden tumor population can decide if #immunotherapy works or fails In CRC A single clonal neoantigen → ~70% durable response vs ~10% without it dMMR tumors respond but still fail due to heterogeneity ICI clears immunogenic clones → low-immunogenic subclones survive,
👉The review provides a mechanistic roadmap for using #nanomaterial-based strategies as pathway-matched, programmable interventions to overcome primary #resistance to PD-1/PD-L1 inhibitors. PD-1/PD-L1, #immunotherapy, immune resistance, nanomaterials 👀oaepublish.com/articles/cdr.2…
🚀 Enara Bio showcases ENA101 cancer immunotherapy at AACR Advancing next-gen immune-targeted oncology therapies. 👉 cgxpwire.com/biopharma/enar… #Immunotherapy #Oncology #AACR
The market for our senolytic #immunotherapy #senovax is literally unlimited. Who would have thought senescence cells cause #cardiac arrhythmia?? heartrhythmjournal.com/article/S1547-…
“Clear cell ovarian cancer behaves differently. Not chemo-driven… but immune responsive. Phase 2 MoST-CIRCUIT shows Nivo+Ipi with 54% ORR and durable responses. Time to rethink biology. 🔥 #MVOnco #GynOnc #Immunotherapy”
#ESMORareCancers26: Adding first-line #immunotherapy to methotrexate improved response in patients with low-risk gestational trophoblastic neoplasia (#GTN) but must be balanced w/ safety & fertility considerations. ➡️Check out the #ESMODailyReporter: ow.ly/1gXW50YsKII
Essen Biotech trial radar: NCT06532812 (BAH249) — TIL + immunotherapy for refractory breast cancer. Talk to your oncology team. #Immunotherapy #oncology #hematology #CancerResearch #EssenBiotech #ClinicalTrials #Cancer #Genetherapy #CancerTrials #CART #TIL #NK #Breastcancer
.@DrTylerStewart, MD, @UCSD, provides a clear rationale for integrating #immunotherapy into the perioperative management of muscle-invasive bladder cancer. #BladderCancer #Urology #MIBC
Immunotherapy for Solid Tumors Enhanced by Metabolite-Sensing Receptors A new approach engineers immune cells to recognize byproducts of cancer cells to trigger migration toward the tumor @LivnatJerby @Stanford #immunotherapy #cancercells #tumors #GPCR hubs.li/Q048gZQd0
The first #cancer we @immortabio are treating with our #senovax #immunotherapy is #lungcancer targetedonc.com/view/senovax-i…
🧬 #ScienceSaturday ❓ What if we could block cancer’s ability to survive in low-oxygen environments and make #immunotherapy more effective? ➡️ In a new study published in the Journal of Experimental Medicine (@JExpMed), researchers developed dual inhibitors targeting HIF-1 and
#OncoTwitter #Immunotherapy #chemotherapy #radiationtherapy @OncoAlert @myESMO @ESMO_Open @JCO_ASCO 📚 Mager KL, et, al. JAMA 2026 Apr 13. 🌐 10.1001/jama.2026.2248 ♾ jamanetwork.com/journals/jama/…
Great new paper in Cell 😎 What if we’ve been targeting the wrong thing in solid tumors? uPAR CAR T cells don’t just attack cancer cells but instead they dismantle the entire tumor ecosystem. Tumor + stroma + senescence. A potential paradigm shift. #uPAR #Immunotherapy 👇👇 A
cell.com
A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
Synergizing with senescence-inducing therapies, uPAR CAR T cells eradicate primary and metastatic solid tumors with minimal myelodepletion by targeting both tumor cells and the stroma in preclinical...
$IMNN: Enrollment Ahead of Schedule in P3 Ovarian Cancer Trial #biopharma #immunotherapy #vaccines #DNA buff.ly/254Tg6g
SRSF1 inhibition enhances #Cancer #Immunotherapy by restoring CD8⁺ T-cell function and disrupting tumor metabolism, with TN2008 showing improved #Antitumor responses in preclinical models. #STTT #OpenAccess: doi.org/10.1038/s41392…
The latest Labmate UK & Ireland eBulletin explores how emerging evidence continues to refine clinical insight & #laboratory capability across #cardiology, #immunotherapy, #neurology & analytical science👉 ilmt.co/TL/O8Rp Subscription is free👉 ilmt.co/TL/jzlL
Bowel cancer patients stayed cancer-free for nearly three years after immunotherapy before surgery in a clinical trial. 🔗 Full story: buff.ly/uuTK3L0 #BowelCancer #CancerResearch #Immunotherapy #ClinicalTrial #UKHealth
👉The review provides a mechanistic roadmap for using #nanomaterial-based strategies as pathway-matched, programmable interventions to overcome primary #resistance to PD-1/PD-L1 inhibitors. PD-1/PD-L1, #immunotherapy, immune resistance, nanomaterials 👀oaepublish.com/articles/cdr.2…
🚀 Enara Bio showcases ENA101 cancer immunotherapy at AACR Advancing next-gen immune-targeted oncology therapies. 👉 cgxpwire.com/biopharma/enar… #Immunotherapy #Oncology #AACR
🧬 We're glad to share the #MDPI Workshop "Cutting-Edge Advances in Cancer Immunology & Immunotherapy" 📅 8 May 2026 📍University of Southern California (USC), USA Meet our prestigious speakers🌟 🔗Free Register: forms.office.com/e/XZweVunq25 #CancerResearch #Immunotherapy
Sequential targeting (CD33 then CD123) is being studied to broaden AML coverage. See NCT06420063 (BAH244). #Immunotherapy #oncology #hematology #CancerResearch #EssenBiotech #ClinicalTrials #Cancer #Sicklecell #Genetherapy #CancerTrials #Patientcare #Health #CART #TIL #NK
CAR T cell therapy uses immune cells to target resistant cancers offering personalized advanced treatment and hope #CARTTherapy #Immunotherapy #CancerCare #Oncology #AdvancedTreatment consult specialist today #DrGVasuBabu #OncologistIndia #MedicalOncologist #HematoOncologist
Seminar on Agilent Dako's PD-L1 Join us at Anderson Diagnostics and Labs, Chennai for an insightful session on the evolving role of PD-L1 testing in immunotherapy and precision oncology. Registration Link: docs.google.com/forms/d/e/1FAI… #PDL1 #CompanionDiagnostics #Immunotherapy
📊 Study finds increased adenoma risk after ICI-related colitis, with a sharp rise around ~7 months. What does this mean for surveillance? clinicaloncology.com/a/5zcBAA/t #Oncology #Immunotherapy #GI
💬 What matters most before starting IO + TACE in HCC? 🧬 Immune profiling ⚠️ Liver function 📊 Toxicity prediction 🎯 Tumor response potential Vote & discuss 👇 #HCC #Immunotherapy @ozdogan_md @AustinBourgeois @pashtoonkasi @SuyogCancer @DrAngelaLamarca @jryckman3 @NiuSanford
🛡️ Predicting Severe irAEs in HCC After TACE + Immunotherapy Can baseline immune profiling identify patients at risk for severe immune-related adverse events? 🔗f.oaes.cc/xmlpdf/publish… #HCC #Immunotherapy #TACE #PrecisionMedicine
🛡️ Predicting Severe irAEs in HCC After TACE + Immunotherapy Can baseline immune profiling identify patients at risk for severe immune-related adverse events? 🔗f.oaes.cc/xmlpdf/publish… #HCC #Immunotherapy #TACE #PrecisionMedicine
CD24a acting as a "don't attack me" badge...... What happens if CD24a is removed? (0:38-0:45) #CD24a #ImmuneEvasion #Immunotherapy #Macrophages Learn more: buff.ly/NQdVcoR
The optimization of CAR T-cell therapy is crucial for enhancing patient outcomes, particularly in cancer treatments. I'm curious, are the guidelines addressing both efficacy and safety aspects? How do they propose managing the long-term side effects that may arise? #ImmunoTherapy
👀 A deep learning platform may help predict how people with advanced #LungCancer will respond to #immunotherapy. Healio spoke with Dr. Rukhmini Bandyopadhyay, PhD, @UTMDAnderson about a biology-guided #AI model presented at #AACR26 @AACR 👇 vist.ly/4z5mg
Building foundation models of the tumor genome with @TreyIdeker from @UCSDHealth at @AACR AM 2026. Dr. Ideker utilized #ProjectGENIE data to predict tumor evolution and to predict responses to #immunotherapy and chemotherapy. #AACR26 #SU2C
At @AACR, excited to see how AI is shaping the future of cancer care. Nice work from Rukhmini Bandyopadhyay (@UTMDAnderson) on a deep learning pathomics platform to help predict #immunotherapy response in lung cancer. #AACR26 Read more at aacr.org/about-the-aacr…
$IMNN: Final Data from Phase 2 Ovarian Cancer Trial Shows Improvement in Survival of Greater Than One Year #biopharma #immunotherapy #vaccines #DNA buff.ly/05CmgkP
A pancreatic cancer vaccine acts as immunotherapy, targeting and eliminating residual cancer cells post-treatment. It's a crucial step in the fight against this disease. #CancerResearch #Immunotherapy
$MDNAF $MDNA.to ✅ First-in-human study targeted for 2026 ✅ IND submission expected H2 2026 Preparing for clinical entry! #Immunotherapy #ClinicalTrials #MDNA113 #Cancer
New article alert from JCO: RAPIDO & PRODIGE-23 proved TNT works. NEOTERIC asks how to make TNT smarter. Signal-seeking today. Practice-changing tomorrow? #rectalcancer #immunotherapy #medtwitter #medscape @ASCO @JCO_ASCO @OncoAlert @OncBrothers @CancerNetwrk
PD-L1 predicts in metastatic… but not early cancer. Why? • Metastatic → exhausted immunity • Needs PD-L1 removal • Early → strong immunity • Builds new response • Same shield, different outcome #MVOnco #Oncology #Immunotherapy
One hidden tumor population can decide if #immunotherapy works or fails In CRC A single clonal neoantigen → ~70% durable response vs ~10% without it dMMR tumors respond but still fail due to heterogeneity ICI clears immunogenic clones → low-immunogenic subclones survive,
Phase 3 (PRESERVE-003): Gotistobart vs Docetaxel Post PD-(L)1 resistant sqNSCLC Early overlap → late separation (~6 months) HR 0.46 | Durable OS benefit 👉 Classic immunotherapy effect #MVOnco #NSCLC #Immunotherapy #LungCancer
Allergy to peanuts affects approximately 2% of individuals in the US. 💡 This JAMA Insights discusses #PeanutAllergy, including diagnosis, introduction of peanuts to infant diet, and #immunotherapy options. ja.ma/4bnHMCf
#ESMORareCancers26: Adding first-line #immunotherapy to methotrexate improved response in patients with low-risk gestational trophoblastic neoplasia (#GTN) but must be balanced w/ safety & fertility considerations. ➡️Check out the #ESMODailyReporter: ow.ly/1gXW50YsKII
“Clear cell ovarian cancer behaves differently. Not chemo-driven… but immune responsive. Phase 2 MoST-CIRCUIT shows Nivo+Ipi with 54% ORR and durable responses. Time to rethink biology. 🔥 #MVOnco #GynOnc #Immunotherapy”
Some undifferentiated #sarcomas appear to be responsive to #immunotherapy but reliable #biomarkers are needed. @pawel_sobczuk explains more in his Opinion piece in the #ESMODailyReporter 📌 ow.ly/STcv50YtqLb #ESMORareCancers26
📌@MdCurioni discusses the challenges of overcoming acquired resistance to #immunotherapy in #NSCLC, highlighting some positive and negative trial data from #ELCC26. Learn more in the #ESMODailyReporter: ow.ly/5vik50YA1aL
#Ovariancancer finally got its first OS benefit from #immunotherapy. #KEYNOTE_B96: #pembrolizumab plus weekly paclitaxel+/- Bev. HR 0.76 in CPS ≥1. HR 0.82 ITT. Lancet, tonight at #SGO2026. ** Two prior phase 3 ICI trials in this disease failed. Both targeted #PDL1.
We often use PD-L1 or CD8 density to predict response to #immunotherapy But this study suggests something else may matter more: DISTANCE In resectable NSCLC treated with neoadjuvant chemoimmunotherapy (multiplex spatial analysis, n=44), response was best predicted by how close
The morning advantage… Patrick G. Lyons @_plyons & team @washumedicine perform an observational study of 715 patients, reporting a connection between the time of day when CAR T-cell cancer #immunotherapy is administered and its effectiveness: doi.org/10.1172/jci.in…
Crossed 160 publications📝today. ✍🏽Building upon #immunotherapy💉, novel clinical trials, and #liquidBiopsies🩸 for patients with colorectal cancer and other malignancies. Latest article with⭐️@mariaf_teix 🔗: @OncoAlert sciencedirect.com/science/articl… @cityofhopeoc #CRCSM #cancer
Immunotherapy in gastric cancer — who really benefits? ✔️ MSI-H = best responses ✔️ PD-L1 helps (but not enough) ✔️ HER2+ → triplet therapy rising ❗ Most patients still don’t respond 🚀 Next step: smarter biomarkers + combinations #Oncology #CancerResearch #Immunotherapy
🧬 #ScienceSaturday ❓ What if we could block cancer’s ability to survive in low-oxygen environments and make #immunotherapy more effective? ➡️ In a new study published in the Journal of Experimental Medicine (@JExpMed), researchers developed dual inhibitors targeting HIF-1 and
Congrats to Prof. Yang-xin Fu from @MedTsinghua on being named a 2025 @Clarivate Highly Cited Researcher for the seventh consecutive year! 🎉 A pioneer in cancer #immunotherapy, he continues to fuel breakthroughs in developing antibody-cytokine fusion protein or vaccine.
#HT26 Abstract submission closing soon! Share your research at #IASLC HT26 and join global experts exploring resistance to #immunotherapy. 🇮🇪 Dublin, Ireland 🗓️June 26–27 📝Deadline: April 15 bit.ly/3NbSROT #LungCancer #Oncology #Research
#ESMORareCancers26: ARCAGEN highlights a gap between molecular profiling and treatment in advanced #RareCancers. Among patients with clinically actionable alterations, only 15% received matched targeted therapy or #immunotherapy. #ESMODailyReporter 📌 ow.ly/yk5150YFAXT
Immunotherapy is not just tumor biology. Thymic health predicts outcomes: • PFS HR 0.65 • OS HR 0.56 • Independent of PD-L1 & TMB • Even in PD-L1 <1% → ↓ progression ~44% We may be treating the tumor… But the response depends on the patient’s immune age. #Immunotherapy
#ELCC26: Non-inferiority for overall survival was demonstrated with late versus early IV #immunotherapy administration in the ETOP-Roche i-TiMES meta-analysis of 8 trials in ##LungCancer. Read more in the #ESMODailyReporter 📌ow.ly/LYNw50YzJ72
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