#innateimmunity search results
Excited to host Dr. Mikala Egeblad at the next #KomenBreastCancerForum 11/19- 9am NB-5.124 @UTSWMedCenter @UTSWCancerBio @UTSWScience @UTSW_Pathology @UTSWMolBiol @utswimmuno @megeblad @JohnsHopkins @AriellaHanker @QingZhangLab #InnateImmunity #Metastasis #TMEhost See you all !!
We are pleased to present a special collection highlighting recent findings in the #InnateImmunity field. It spotlights cutting-edge research on the mechanistic aspects of innate immune signaling upon #infection, in #autoimmunity, & in #neurodegeneration hubs.la/Q03KlMjS0
🙌Hey @utswcancer @UTSWMedCenter @UTSWCancerBio @UTSWHemeOnc @UTSWScience @UTSW_Pathology @UTSWMolBiol @utswimmuno DON'T MISS the next #KomenBreastCancerForum feat. Dr. Mikala Egeblad @megeblad @JohnsHopkins 11/19 9am IN PERSON #InnateImmunity #Metastasis #TMEhost @MalladiLab
My continued biological education #LiquidLiquidPhaseSeparation Phase separation as a new form of regulation in #InnateImmunity Sensor-Adaptor-Transcription factor-Effector DNA sensing cGAS-STING-IRF3 RNA sensing PKR Inflammasome NLRP6 Ubiquitination (TRIM5α, NEMO)/SUMOylation…
Excited to share this article with @Chauhanlab_ILS & team @ccmb_csir on intricate cross-talk b/w #Autophagy & #InnateImmunity. As my lab is starting to focus on innate immune responses against Fungal Pathogens, this was a super useful proces😀 Link: sl1nk.com/Eu2Q6
The STING pathway drives non-inflammatory #neurodegeneration in NGLY1 deficiency, say Kun Yang, Nan Yan and colleagues (UT Southwestern Medical Center): hubs.la/Q03Kp2rQ0 From our Pattern Recognition Receptors & Beyond #InnateImmunity collection: hubs.la/Q03Kp5hv0
Isoform-specific mouse KO shows ADAR1p150 required in development and adults for hematopoiesis and suppression of interferon signaling #rnaediting #innateimmunity bit.ly/3K4vp1k
Congratulations to @JExpMed Editorial Board Co-Chair Carl Nathan on receiving the 2025 David & Beatrix Hamburg Award from @theNAMedicine for his fundamental work in improving understanding of #InnateImmunity: hubs.ly/Q03LbPyD0
Alexander Yang, @DonnaFarber3 and colleagues @columbiamed show how lung tissue resident memory T cells optimize protection through IL-10 production which regulates #macrophage-mediated #inflammation in the lungs. hubs.la/Q03NksgF0 #InnateImmunity #MucosalImmunology
A viral E3 ubiquitin ligase produced by herpes simplex virus 1 inhibits the NLRP1 #inflammasome, say @JustKOS1, @VirulentMind et al. hubs.la/Q03KmbpB0 From our Pattern Recognition Receptors & Beyond #InnateImmunity collection: hubs.la/Q03Km5Qm0
Hanson Tam, Jason Cyster et al. @UCSF identify GPR34 as a splenic cDC1 receptor that is required for efferocytosis and for the cross-presentation of apoptotic cell–associated antigen to CD8 T cells. hubs.ly/Q03SqBVm0 #InnateImmunity #inflammation @HHMINEWS
Join us at 2pm for talks on the regulation of innate inflammatory responses by cell volume and how mechanical stress boosts NLRP3 inflammasome activation at @Inflammazoom, our free webinar series on #innateimmunity Use the link to join: bit.ly/4cqHZo2
Bernaleau et al @RebsamenLab @unil use a loss-of-function genetic screen to identify ER-resident CCDC134 as an essential regulator of TLR responses that binds & stabilizes the TLR chaperone Gp96. hubs.la/Q03KmDy00 From our #InnateImmunity collection: hubs.la/Q03KmGP_0
Ru et al. show that the accumulation of RNA lariats in human DBR1-deficient cells impairs #StressGranule assembly–mediated PKR activation, and thereby cell-intrinsic antiviral immunity. hubs.la/Q03KmhrH0 From our #InnateImmunity collection: hubs.la/Q03KmmHk0
Are you excited about #innateimmunity #nucleicacidsensing #interferons #ADAR1 #ncRNA #viralinfection #reproductiveimmunology? Want to live & work in Leiden? We’re recruiting a PhD student or post-doc for our team @LUMC_Leiden @GlobalLumc 🥳 🧬🦠🧫🥼👩🏻🔬🔬🇳🇱 Please RT far & wide!
Wouters, @IsabelleMeyts et al. @KU_Leuven show that next to biallelic deleterious mutations in ADA2, monoallelic dominant negative missense variants in ADA2 can also underlie ADA2 deficiency. hubs.la/Q03KnJ4K0 From our #InnateImmunity collection: hubs.la/Q03KnY4_0
Join us in Boston this December for our first-ever in-person @InflammaZoom, featuring insightful talks from leaders in #InnateImmunity. Register here: abcam.com/events/innate-… @ClareBryant13 @dave_boucher @ybri_uoy @rebecca_coll @qubelfast @JelenaLab
Studies show higher rates of developmental delays, asthma, and chronic diseases in vaccinated children compared to unvaccinated. Vaccinating a developing immune system may suppress immunity, leading to chronic disorders. #VaccineSafety #InnateImmunity
Hanson Tam, Jason Cyster et al. @UCSF identify GPR34 as a splenic cDC1 receptor that is required for efferocytosis and for the cross-presentation of apoptotic cell–associated antigen to CD8 T cells. hubs.ly/Q03SqBVm0 #InnateImmunity #inflammation @HHMINEWS
Excited to host Dr. Mikala Egeblad at the next #KomenBreastCancerForum 11/19- 9am NB-5.124 @UTSWMedCenter @UTSWCancerBio @UTSWScience @UTSW_Pathology @UTSWMolBiol @utswimmuno @megeblad @JohnsHopkins @AriellaHanker @QingZhangLab #InnateImmunity #Metastasis #TMEhost See you all !!
Activating the Body’s Innate Power to Heal 📞 Call us for a FREE consultation: +1 319-380-4380 👉 Follow for more healing science @thehealingws #NaturalHealing #InnateImmunity #SoftWaveTherapy #FunctionalMedicine #CellularHealing #InflammationRecovery #TheHealingWS
🙌Hey @utswcancer @UTSWMedCenter @UTSWCancerBio @UTSWHemeOnc @UTSWScience @UTSW_Pathology @UTSWMolBiol @utswimmuno DON'T MISS the next #KomenBreastCancerForum feat. Dr. Mikala Egeblad @megeblad @JohnsHopkins 11/19 9am IN PERSON #InnateImmunity #Metastasis #TMEhost @MalladiLab
Studies suggest vaccinated groups may experience higher rates of chronic and infectious diseases compared to unvaccinated groups, indicating a potential suppression of innate immunity. #VaccineStudy #InnateImmunity
Alexander Yang, @DonnaFarber3 and colleagues @columbiamed show how lung tissue resident memory T cells optimize protection through IL-10 production which regulates #macrophage-mediated #inflammation in the lungs. hubs.la/Q03NksgF0 #InnateImmunity #MucosalImmunology
Lioba Koerner, Xiaoming Li, Eveline Silnov, Lucie Laurien, and Manolis Pasparakis show that RIPK1 autophosphorylation at S161 is crucial for regulating #CellDeath and #inflammation. hubs.la/Q03Lb94h0 From our #InnateImmunity collection: hubs.la/Q03LbfdM0
Han et al show that RIPK1 S161 autophosphorylation promotes further autophosphorylation & can substitute for RIPK1 kinase activity in TNF-induced #necroptosis-mediated cecal damage & mouse death hubs.la/Q03LbcWG0 From our #InnateImmunity collection: hubs.la/Q03Lb94d0
The STING pathway drives non-inflammatory #neurodegeneration in NGLY1 deficiency, say Kun Yang, Nan Yan and colleagues (UT Southwestern Medical Center): hubs.la/Q03Kp2rQ0 From our Pattern Recognition Receptors & Beyond #InnateImmunity collection: hubs.la/Q03Kp5hv0
Wouters, @IsabelleMeyts et al. @KU_Leuven show that next to biallelic deleterious mutations in ADA2, monoallelic dominant negative missense variants in ADA2 can also underlie ADA2 deficiency. hubs.la/Q03KnJ4K0 From our #InnateImmunity collection: hubs.la/Q03KnY4_0
Wenjie Zhu, Xiaoyan Xu, Rachel Caspi @rcaspi @NatEyeInstitute @NIH et al. show that Vγ6 γδ T cells sense commensals via TLR2 to fuel IL-17A-mediated barrier defense at the ocular surface. hubs.la/Q03KnGNW0 From our #InnateImmunity collection: hubs.la/Q03KnN7v0
Discovery of potent and selective inhibitors of human #NLRP3 with a novel mechanism of action, by Kevin Wilhelmsen, @Rebecca_Coll et al: hubs.la/Q03KmYFh0 From our Pattern Recognition Receptors & Beyond #InnateImmunity collection: hubs.la/Q03Kn0qS0 #Inflammasome
Bernaleau et al @RebsamenLab @unil use a loss-of-function genetic screen to identify ER-resident CCDC134 as an essential regulator of TLR responses that binds & stabilizes the TLR chaperone Gp96. hubs.la/Q03KmDy00 From our #InnateImmunity collection: hubs.la/Q03KmGP_0
Ru et al. show that the accumulation of RNA lariats in human DBR1-deficient cells impairs #StressGranule assembly–mediated PKR activation, and thereby cell-intrinsic antiviral immunity. hubs.la/Q03KmhrH0 From our #InnateImmunity collection: hubs.la/Q03KmmHk0
Saidoune, Gilliet, @AhmadYatim_ et al. show that excessive TLR7 responses to #SARSCoV2 by pDCs are linked to I-IFN–driven chilblain development. hubs.la/Q03KmjQg0 From our Pattern Recognition Receptors & Beyond #InnateImmunity collection: hubs.la/Q03Kmq4f0
A viral E3 ubiquitin ligase produced by herpes simplex virus 1 inhibits the NLRP1 #inflammasome, say @JustKOS1, @VirulentMind et al. hubs.la/Q03KmbpB0 From our Pattern Recognition Receptors & Beyond #InnateImmunity collection: hubs.la/Q03Km5Qm0
.@Yaelalippe, @msdiamondlab et al. show that fetal MAVS & type I IFN signaling pathways control #Zika virus infection in the placenta and maternal decidua. hubs.la/Q03KlVhL0 From our Pattern Recognition Receptors & Beyond #InnateImmunity collection: hubs.la/Q03KlWk_0
Join us online today for the first @InflammaZoom of 2024, featuring @anandparas @imperialcollege and Petr Broz @broz_lab @unil bit.ly/3IbSUE3 #inflammasome #innateimmunity #immunology #webinar
Kickstart your year with insights into #innateimmunity and #inflammasome biology! Register for the #InflammaZoom, our free monthly webinar series. Next session: January 20 at 8.00am GMT w/ @keshu_VRimmCh -@iiscbangalore & @mere_conjecture - @UTAS_ bit.ly/3DP7H8W
We are pleased to present a special collection highlighting recent findings in the #InnateImmunity field. It spotlights cutting-edge research on the mechanistic aspects of innate immune signaling upon #infection, in #autoimmunity, & in #neurodegeneration hubs.la/Q03KlMjS0
Discovery of potent and selective inhibitors of human #NLRP3 with a novel mechanism of action, by Kevin Wilhelmsen, @Rebecca_Coll et al: hubs.la/Q03KmYFh0 From our Pattern Recognition Receptors & Beyond #InnateImmunity collection: hubs.la/Q03Kn0qS0 #Inflammasome
My continued biological education #LiquidLiquidPhaseSeparation Phase separation as a new form of regulation in #InnateImmunity Sensor-Adaptor-Transcription factor-Effector DNA sensing cGAS-STING-IRF3 RNA sensing PKR Inflammasome NLRP6 Ubiquitination (TRIM5α, NEMO)/SUMOylation…
Join us at 2pm for talks on the regulation of innate inflammatory responses by cell volume and how mechanical stress boosts NLRP3 inflammasome activation at @Inflammazoom, our free webinar series on #innateimmunity Use the link to join: bit.ly/4cqHZo2
Join us in Boston this December for our first-ever in-person @InflammaZoom, featuring insightful talks from leaders in #InnateImmunity. Register here: abcam.com/events/innate-… @ClareBryant13 @dave_boucher @ybri_uoy @rebecca_coll @qubelfast @JelenaLab
Isoform-specific mouse KO shows ADAR1p150 required in development and adults for hematopoiesis and suppression of interferon signaling #rnaediting #innateimmunity bit.ly/3K4vp1k
💡 Looking for a source of inspiration for your #innateimmunity and #inflammasome biology research? 💡 Check out @InflammaZoom, a free webinar series organized in collaboration with @ClareBryant13! Register once to access all 2024 sessions 👇 bit.ly/48gQAGs
🎉New in #JEV🎉 Authors Jiaqi Liang and Hang Yin from @Tsinghua_Uni have elucidated the mechanism and function of the translocation of STING into #EVs adding to the understanding of STING activity regulation in #innateimmunity. Read the full article here👉 bit.ly/3Z7YPAg
Are you excited about #innateimmunity #nucleicacidsensing #interferons #ADAR1 #ncRNA #viralinfection #reproductiveimmunology? Want to live & work in Leiden? We’re recruiting a PhD student or post-doc for our team @LUMC_Leiden @GlobalLumc 🥳 🧬🦠🧫🥼👩🏻🔬🔬🇳🇱 Please RT far & wide!
Missed the last @inflammazoom session on July 3? Catch up on-demand here! bit.ly/3JVXNm6 @avi_cambi @cinflammasome @Toniolo_chiara #inflammasomebiology #innateimmunity #pyrin
We are #recruiting! If you are looking for a #postdoc position in the fields of #innateimmunity and #inflammation, contact us! Positions are for a min of 2 years, starting Oct 2023, on the vibrant main @CNRS_OccitaniE campus in Montpellier, within the @IGMM_Montpel - Please RT!
Excited to share this article with @Chauhanlab_ILS & team @ccmb_csir on intricate cross-talk b/w #Autophagy & #InnateImmunity. As my lab is starting to focus on innate immune responses against Fungal Pathogens, this was a super useful proces😀 Link: sl1nk.com/Eu2Q6
Excited to host Dr. Mikala Egeblad at the next #KomenBreastCancerForum 11/19- 9am NB-5.124 @UTSWMedCenter @UTSWCancerBio @UTSWScience @UTSW_Pathology @UTSWMolBiol @utswimmuno @megeblad @JohnsHopkins @AriellaHanker @QingZhangLab #InnateImmunity #Metastasis #TMEhost See you all !!
If you're at the @AegeanConf International Conference on #InnateImmunity, don't miss the opportunity to talk to our Editorial Board Member, @SiMingMan1
A pair of papers in @SciSignal reveals how #SARSCoV2 and other #coronaviruses suppress innate immune responses in infected cells–and suggest that targeting this pathway can slow viral replication in culture. #InnateImmunity scim.ag/2wX scim.ag/2wY
Alexander Yang, @DonnaFarber3 and colleagues @columbiamed show how lung tissue resident memory T cells optimize protection through IL-10 production which regulates #macrophage-mediated #inflammation in the lungs. hubs.la/Q03NksgF0 #InnateImmunity #MucosalImmunology
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