#protac 搜尋結果
🇺🇸Streamlight PROTAC 2AA-X USB MULTI-FUEL TACTICAL FLASHLIGHT ストリームライトの新作 単三 2本サイズの細身のタクティカルフラッシュライトです。 専用充電池使用で 550／40lm 単三アルカリ2本使用で 270／18lm #Streamlight #Protac #池袋 #東京 #懐中電灯 #専門店 #ezlitetokyo
#STREAMLIGHT #PROTAC #1L-1AA 旧CREE XP-G2 新 Osram P9 H2T カスタム CREE XP-P 6500K Nichia 219C V2 5000K 90CRI LUMINUS SST-12 5000K ※非高演色 比較レビューです。 け、掲載は後ほど、、
今日のビクトリー🏆✨🔦🦸(´-(ェ)-`;)♥ ・H2T SL 1L1AA ブラック LED換装カスタム LUMINUS SST-12 95CRI 4000K #Steamlight #ProTac #1L1AA #H2T #アカリセンター
今日のビクトリー🏆✨🔦🦸(´-(ェ)-`;) ・H2T PT-1AAA-NICHIA-30K SL PROTAC 1AAA LED換装カスタム NICHIA 519A R9080 3000K #Streamlight #ProTac #1AAA #ストリームライト #H2T #アカリセンター
Happy new year 2023 !!! I hope that this twitter account will always be useful to all about #PROTAC technology and other #TPD😉
STREAMLIGHT PROTAC 2AA CT みんな大好きストリームライト！ 10tap⇨H➞St➞L / H / L➞H 公称より明るく感じます✨ フリッカーも出る様子がなくひと安心(*´ω｀*) クリックしづらい点は好みが別れるかも …続く #STREAMLIGHT #PROTAC2AA #PROTAC #STREAMLIGHTSTRONG
Introducing ARV-393: an ultra-potent & rapid #PROTAC degrader of BCL6 with consistent PK properties across species. Of note, a PROTAC with an occupancy-drug-like PK profile to overcome fast protein synthesis rebound. Neosubstrate selectivity: “clean enough to progress” #AACR24
The Chamessian Lab @WashUPain is recruiting a #postdoctoral research associate to build on the foundational findings from our recent preprint showing that ion channels can be degraded by PROTACs. #TPD #PROTAC #drugdiscovery #pain #ionchannels. We're a fun group with an…
Sulfur exchange chemistry is well-suited to the development of histidine targeting small molecule protein ligands and drugs. Try our building blocks in-stock lnkd.in/eXKDDzGT or order Make-On-Demand building blocks lnkd.in/ekP-FY-6! #Enamine #PROTAC #drugdiscovery
Congratulations Dr. Craig M. Crews, the recipient of the annual Kimberly Prize in Biochemistry and Molecular Genetics! Inspiring talk on the clinical promise of #PROTAC, #RIPTAC and #PHOSTACs @CraigMCrews @NUFeinbergMed @NU_BMG_SQE @ShilatifardLab @YaleMed @ArvinasInc
STREAMLIGHT PROTAC 2AA-X 話題の2AA(＆専用バッテリー)ライト。 フォワードクリッキー 10タップも健在。 お約束の10タップでL→HやHシングルにできるのはとても良いです(*´ω｀*) ボディの造りも非常に良く流石だと思います。 …続く #STREAMLIGHT #PROTAC #2AAX
What makes #PROTAC molecules unique? They contain two binding domains—one binds to disease-causing proteins, the other to an E3 ligase, marking proteins for elimination by the proteasome or “garbage disposal of the cell.” Each PROTAC can repeat this process many times. Explore…
I am hiring 1-2 postdocs in #medicinalchemistry to work on #PROTAC and inhibitor projects as part of highly interdisciplinary collaborations with biologists and others. Please send a CV to apply to [email protected] to apply.
I’m back at work in @UoDCeTPD today, making some interesting #PROTAC linkers - this one had some really nice colour changes so I made a quick clip when I was quenching. #TPD #ChemTwitter
I am proud to share our #PROTAC library approach to access #CRBN PROTACs via photoinduced C-C coupling and amide coupling in one-pot fashion. Check it out as preprint here: chemrxiv.org/engage/chemrxi….
Behördenzubehör: Neue taktische Waffenlampe von #Streamlight! Die #ProTac® Rail Mount HL-X Pro gun-mounted light mit 1,000 Lumen und 447 m Reichweite mit einem Jack-Cap™ tail cap switch. Facebook - StreamlightDE #Twitter - StreamlightDE #Instagram - Streamlight_europe
Grateful for the opportunity to present my poster at the 7th TPD & IP It was a rewarding experience to share my work TPD and engage with the leading scientists in the field. Thank you Women in TPD for all the support. #TPD #PROTAC #bifunctionalmolecules #7thTPD #womeninTPD
🔥Hot Off the Press| A study reports a covalent #PROTAC that precisely degrades #ZBP1, a key inflammation regulator in viral infection. The DNA aptamer + covalent linker + VHL design boosts stability, selectivity, and antiviral/anti-inflammatory activity.ow.ly/xzrr50XsyQ6
Pharmaron supports 8 protein degraders in clinical trials, 80 in preclinical stages, and over 100 ongoing projects! Learn how we drive targeted protein degradation from discovery to clinical trials #TPD #DrugDiscovery #PROTAC
Please help spread the word! findaphd.com/phds/project/s… 4-year BBSRC-funded SWBIO PhD studentship available in my lab #TPD #PROTAC #ubiquitin #Aptamer with Prof Matthew Crump @BristolChem, Prof Christiane Berger-Schaffitzel @BristolBiochem @scottlovell34). Deadline 03/12/25
🔥Hot Off the Press | #Nano -#PROTAC: Dual-Target Protein Degrader 🧬A PSMA-targeted Nano-PROTAC using self-assembling nanotech can simultaneously degrade #AR & #HSP90, suppressing castration-resistant prostate cancer (#CRPC) and prolonging survival. · 80% AR & 65% HSP90…
🚀From Bench to Paper | Tackling CRPC Resistance: A Nano-PROTAC Advance New research in Signal Transduction and Targeted Therapy highlights a promising #Nano-#PROTAC for castration-resistant prostate cancer (#CRPC). This PSMA-targeted agent degrades #AR, its chaperone #HSP90,…
The #ProTac 2AA-X delivers serious performance in a lightweight, everyday-carry design. Runs on AA or lithium batteries, giving you flexibility in the field or on the job. Dual fuel (AA or lithium) Durable anodized aluminum body Pocket clip for easy carry IPX7 waterproof rating.
Discover cutting-edge tools for targeted protein degradation with Pharmaron’s custom cell lines and assays. Explore our 8+ years of experience in protein degrader discovery! #TPD #PROTAC #DrugDiscovery #Proteindegraders
Article✍️#PROTAC-loaded #nanocapsules degrading #BRD4 for #radio-#chemotherapy #sensitization in #glioblastoma. From Dr. Sun @FudanUniversity; @FudanUniv. sciencedirect.com/science/articl….
Article✍️#Photodynamic enhancement of #PROTAC #prodrug activation in #hypoxic #tumors. From Dr. Li @HunanUniversity; @HuNanUni. sciencedirect.com/science/articl….
Article✍️#Activatable #PROTAC #nanoassembly for #photodynamic #PTP1B proteolysis enhances #glioblastoma #immunotherapy. From Dr. Shim @KoreaInstituteofScienceandTechnology (KIST); @KoreaUniversity; @KonkukUniversity; @EwhaWomansUniversity; sciencedirect.com/science/articl….
"Resolving Enzyme–Substrate–Activator Ambiguity: A Minimalist Enzyme Kinetic Framework for PROTAC Design and Optimization" pubs.acs.org/doi/10.1021/ac… @JMedChem @ACSPublications, @CRUKresearch @CR_UK #PROTAC, #MolecularGlues, #ScienceOfPROTAC, #TargetedProteinDegradation
Inhibiting XIAP / cIAP can make HNSCC chemoRT resistant. Those IAPs are easier to target, but maybe not the major IAPs that mediate the resistance. Will present the FIC #PROTAC anti-BIRC5 as RT sensitiver in #ASTRO2025 #radonc #Glioblastoma #Neurosurgery ascopubs.org/doi/10.1200/JC…
#Streamlight 88062 #ProTac 2L-X 500-Lumen 6800-Candela EDC High Performance Multi-Fuel Tactical #Flashlight 22% off amzn.to/46jlaSa
#FlashlightFriday #Steamlight #ProTac #1L1AA #H2T #ストリームライト #streamlightstrong ・H2T SL 1L1AA コヨーテ LED換装カスタム 高演色 NICHIA 519A 3000K ・H2T SL 1L1AA ブラック LED換装カスタム XP-G4 6500K 70CRI
🇺🇸Streamlight PROTAC 2AA-X USB MULTI-FUEL TACTICAL FLASHLIGHT ストリームライトの新作 単三 2本サイズの細身のタクティカルフラッシュライトです。 専用充電池使用で 550／40lm 単三アルカリ2本使用で 270／18lm #Streamlight #Protac #池袋 #東京 #懐中電灯 #専門店 #ezlitetokyo
🔦💡新入荷/再入荷💡🔦 🇺🇸STREAMLIGHT 🔦PROTAC 2.0 HEADLAMP 2000lms🆕 🔦PROTAC 1AAA 115lms 🔦POLYTAC 600lms BK/CYT/YL #STREAMLIGHT #polytac #protac #ストリームライト #ライト #懐中電灯 #フラッシュライト #懐中電灯専門店 #イージーライト #池袋 ez-lite.com
The Chamessian Lab @WashUPain is recruiting a #postdoctoral research associate to build on the foundational findings from our recent preprint showing that ion channels can be degraded by PROTACs. #TPD #PROTAC #drugdiscovery #pain #ionchannels. We're a fun group with an…
今日のビクトリー🏆✨🔦🦸(´-(ェ)-`;) ・H2T PT-1AAA-NICHIA-30K SL PROTAC 1AAA LED換装カスタム NICHIA 519A R9080 3000K #Streamlight #ProTac #1AAA #ストリームライト #H2T #アカリセンター
Targeted protein degradation in #Cancers Orthodox PROTACs and beyond. In his review, Li et al. introduced the mechanisms, features, and molecular targets of orthodox PROTACs and summarize the #PROTAC #drugs under study. cell.com/the-innovation… #treatment #clinicaltrials
In the Spotlight— MDM2-PROTAC versus MDM2 inhibitors: Beyond #p53 reactivation, by @sylvain_peuget and Galina Selivanova. bit.ly/3LC9ZZk @karolinskainst #PROTAC
Congratulations Dr. Craig M. Crews, the recipient of the annual Kimberly Prize in Biochemistry and Molecular Genetics! Inspiring talk on the clinical promise of #PROTAC, #RIPTAC and #PHOSTACs @CraigMCrews @NUFeinbergMed @NU_BMG_SQE @ShilatifardLab @YaleMed @ArvinasInc
今日のビクトリー🏆✨🔦🦸(´-(ェ)-`;)♥ ・H2T SL 1L1AA ブラック LED換装カスタム XP-G4 6500K 70CRI #Steamlight #ProTac #1L1AA #H2T #アカリセンター
Sulfur exchange chemistry is well-suited to the development of histidine targeting small molecule protein ligands and drugs. Try our building blocks in-stock lnkd.in/eXKDDzGT or order Make-On-Demand building blocks lnkd.in/ekP-FY-6! #Enamine #PROTAC #drugdiscovery
ホントはこれを投稿しようと思ったんですよね。 #PROTAC 90 を #エボルタNEO でデータ取りしました。 気温が高い時期なので、あと15度低ければSTREAMLIGHTの公称グラフにほぼ一致する…かな。
おはようございます✨️ 今日は朝から怖い話をさせていただきます。 #STREAMLIGHT のWEBページから、#PROTAC90 が消えています… ひいいぃぃぃ！ 今日3個、火曜に4個入荷で一旦打ち止め。現在状況確認中です。またご報告しますね
休日の相棒はやっぱりSTREAMLIGHT PROTAC 1L-1AA ライト初心者にもおすすめの一本！ #STREAMLIGHT #PROTAC #PROTAC1L1AA #STREAMLIGHTSTRONG
ARV-766, a #PROTAC androgen receptor degrader, in #mCRPC: Initial results of a phase 1/2 study. Presentation by @DanielPetrylak @YaleCancer. #ASCO24 written coverage by @zklaassen_md @GACancerCenter > bit.ly/3X2jAQq @ASCO
STREAMLIGHT PROTAC 1L-1AA BK&CT 個人的にはカスタム機を除いたら一番好きなライトかもしれません。 #STREAMLIGHT #PROTAC #1L1AA #Flashlight
A new #Protac degrader of the #PXR receptor has been developed in collaboration between our team at @IBMM_Balard and the IGF institute ! Lead compound 7048 degrades the PXR receptor in cellulo and in vivo, opening the way to fight cancer chemoresistance and recurrence !
今日のビクトリー🏆✨🔦🦸(´-(ェ)-`;)♥ ・H2T SL 1L1AA ブラック LED換装カスタム LUMINUS SST-12 95CRI 4000K #Steamlight #ProTac #1L1AA #H2T #アカリセンター
#streamlight #Protac 90 #Protac 90x #Nichia 519A 519Aへの換装ライトをオクとアカリさんで購入。 どちらも右がオリジナルです。 写真だと分かりにくいですが、90が2700kで90xが4000k EDCはもうこれだけあれば良い気がしてきた。
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