#zebrafishfunfacts search results

The first international workshop that focused on #zebrafish was convened in 1990. Sponsored by NIH and NSF, the gathering of ∼40 scientists sought to evaluate the research potential of the tiny fish. Today, nearly 1,800+ zebrafish labs exist worldwide. #ZebrafishFunFacts

#ZebrafishFunFacts: Using the discarded slide film from his doctoral research, Prof Michael Barresi created a mosaic of an adult #zebrafish. Learn about his upcoming art installation on human embryos called 'Using Art to Demystify Science': smith.edu/news-events/ne…

#ZebrafishFunFacts: Known to hobbyists as the leopard Danio, TL or Tüpfel longfin #zebrafish consist of two alleles (leo and lof). leo is a gap junction protein (ncbi.nlm.nih.gov/pmc/articles/P…), while lof is caused by upregulation of a K+ channel (journals.biologists.com/dev/article/14…). 1/2

"Mutations affecting the development of the embryonic zebrafish brain" by first-author @schierlab of Driever Lab detailed important embryological events in #zebrafish brain. This provided the genetic framework for several hundred studies on brain morphogenesis. #ZebrafishFunFacts

Count your somites! To make a vertebra, it takes 120 minutes in mice, 90 minutes in chicks, 30 minutes in zebrafish, and ~4.5 hours in humans. #ZebrafishFunFacts

While Kimmel et al. 1995 standardized the embryonic development of #zebrafish, Parichy et al. 2009 takes it one step further with characterizing postembryonic zebrafish. They establish Standard Length (SL) as measure of developmental progress rather than age. #ZebrafishFunFacts

Published in @Nature (2010) and cited nearly 1,500 times, "Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation" by Jopling et al. was first to describe key processes that are necessary for the regeneration response in fish. #ZebrafishFunFacts

#ZebrafishFunFacts: In a 2016 article on @the_Node titled, "The Doctor of Delayed Publications - The remarkable life of George Streisinger", @mvargam takes the reader down memory lane to provide a life history of the Founding Father of #zebrafish research. thenode.biologists.com/doctor-delayed…

Masters of regeneration? #Zebrafish are capable of regenerating their fins, spinal cord, pancreas, skin, retina, heart, liver, brain, tendons, hair cells, & kidney. For more info on this amazing species, read this primer on regeneration: journals.biologists.com/dev/article/14… #ZebrafishFunFacts

As the most-cited #zebrafish cancer paper, Amsterdam et al. screened hundreds of heterozygous lines for embryonic lethal mutations and found elevated cancer incidence in ribosomal genes. This underappreciated discovery was published @PLOSBiology 20 years ago. #ZebrafishFunFacts

Metcalfe et al. (1985) were first to fully characterize the lateral line (a series of sense organs on skin that detect water flow) in #zebrafish larvae. Included within this seminal piece are meticulous hand-drawings that are commonly found in Kimmel's papers. #ZebrafishFunFacts

“The fish is a frog... is a chicken... is a mouse." In the 1980s, Kimmel defined a crucial stage at the onset of gastrulation when the prospective organization of the entire embryonic body plan emerged. It placed #zebrafish in the context of vertebrate #devbio. #ZebrafishFunFacts

Let's talk about sex! Research suggests natural zebrafish have WZ/ZZ sex chromosomes as evidenced by a single sex-linked region on chromosome 4. This trait is lost in laboratory fish as sex is determined by multiple genes, with influences from the environment. #ZebrafishFunFacts

Scottish Physician Francis Hamilton first described the “beautiful” but “insipid” zebrafish in, “An Account of the Fishes Found in the River Ganges and Its Branches” after capturing it in the River Kosi near Nathpur 🇮🇳 in August 1810. #ZebrafishFunFacts 1/2

With more Danio species being described, the genus was split in 1916 with larger species into Danio and the smaller species into Brachydanio. In 1991, the two genera were recombined and most larger species within genus Danio were reclassified into genus Devario #ZebrafishFunFacts

If you've used @ZFINmod, you may have noticed in situ expression data by Thisse et al. This comprehensive dataset was generated by Profs. Christine and (late) Bernard Thisse. In total, 8,400+ genes are described in 29,000+ figures at different stages. #ZebrafishFunFacts

Due to their aquatic environment, #zebrafish are perfect for small molecule drug screens. Many drugs have been repurposed for novel treatments such as COX inhibitors in leukemia & glucocorticoids in long QT syndrome. For more, read ($): doi.org/10.1038/nrd4627 #ZebrafishFunFacts

#ZebrafishFunFacts: GloFish #zebrafish are prized among hobbyists for vibrant colors. While genetically modified, @US_FDA considers them low risk as they pose no threat to food supply. But there's growing concern after they were found in Brazilian streams: science.org/content/articl…

Published in @Nature & cited over 5K times, Howe et al (2013) outlines the grueling efforts to sequence, assemble, & annotate the #zebrafish genome. In total, 26K protein-coding genes were found with more than 70% of them orthologous to human genes. #ZebrafishFunFacts

Want an easy way to support your model organism databases? Cite them! Depending on the #zebrafish data you from ZFIN, you can show your support by using one of the formats below 🙏#ZebrafishFunFacts #ThatsHowWeShoal