#macrocyclization search results
Online NOW | @J_A_C_S Rapid #Arene #Triazene Chemistry for #Macrocyclization. This strategy should find application in various fields of chemical biology, selective drug delivery, and identification of cyclic peptide hits after library screening. pubs.acs.org/doi/10.1021/ja…
Last speaker for today at #FlowChemistry Asia conference: Prof. Shawn Collins from the Université de Montréal about #macrocyclization processes in #flow @SelectBio
✳️ Gellman and co-authors report a foldamer-catalyzed #macrocyclization of dialdehydes to form 14- to 22-membered rings. ✨ This method can be used as the key step in a total synthesis of robustol! ✨ Great work! 👏 👉 fal.cn/381Tx
A new spotlight on #proximity-induced #one-pot #macrocyclization, where the required electrophile jumps out of the cleavage step: “It's happening like magic!” #peptidecyclization is like a piece of cake! Learn more from @AlexManicardi @GroupObcr pubs.acs.org/doi/10.1021/ac…
Explore how #macrocyclization enhances #kinaseinhibitors, improving selectivity, overcoming resistance, and optimizing #druglikeproperties. Read More: amm-journal.org/index.php/2025… #Macrocyclizationstrategy #Drugdesign #Bindingaffinity #Kinaseselectivity @Science_Open @NUSingapore
Researchers @Fudan University 🇨🇳 focus on #chemoenzymatic synthesis of macrocyclic peptides and polyketides via #thioesterase-catalyzed #macrocyclization. #biosynthesis ➡️ beilstein-journals.org/bjoc/articles/… Thanks for guest editing @LabRudolf, @barra_lena and Takayoshi Awakawa! 💎🔓 #BJOC
One-Step Catalyst-Transfer Macrocyclization: Expanding the Chemical Space of Azaparacyclophanes | Journal of the American Chemical Society @BonifaziGroup @univienna #Catalyst #Macrocyclization #Azaparacyclophanes pubs.acs.org/doi/10.1021/ja…
🔥 New advance article for RSC Chemical Biology! 🔥 Joshua Price @BYU et al exploring "Long-range #PEG stapling: #macrocyclization for increased protein conformational stability and resistance to #proteolysis" 🧐 Get the full #openaccess story here 👉 ow.ly/WIkz50B3l7P
✳️Great Progress in Peptide Chemistry from @MonikaRaj_lab❗👏 Monika Ray and co-workers describe a #stereoselective #macrocyclization of #peptides through click chemistry. Great job! Enjoy reading this #SYNFACT of the month❗👉✨fal.cn/37J1y✨
Stimuli-Responsive Macrocyclization Scaffold Allows In Situ Self-Assembly of Radioactive Tracers for Positron Emission Tomography Imaging of Enzyme Activity @njuniversity #Macrocyclization #Radioactive #Tracers #PET #Enzyme #PositronEmissionTomography pubs.acs.org/doi/10.1021/ja…
pubs.acs.org
Stimuli-Responsive Macrocyclization Scaffold Allows In Situ Self-Assembly of Radioactive Tracers...
Target-enabled bioorthogonal reaction and self-assembly of a small-molecule probe into supramolecules have shown promise for molecular imaging. In this paper, we report a new stimuli-responsive...
Explore the potential of #nitriles 🧪 in #macrocyclization and #bioconjugation with the latest research by @NitscheLab. The game-changing cyanopyridine–aminothiol click reaction enables selective and biocompatible peptide/protein modifications 💪 👉 brnw.ch/21wLKXA
#Macrocyclization of Quinazoline-Based #EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR #L858R and #Del19 | Journal of Medicinal Chemistry pubs.acs.org/doi/abs/10.102…
pubs.acs.org
Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for...
Activating mutations in the epidermal growth factor receptor (EGFR) are frequent oncogenic drivers of non-small-cell lung cancer (NSCLC). The most frequent alterations in EGFR are short in-frame...
Phil S. Baran reviews strained cyclophane natural products: #macrocyclization at its limits bit.ly/NqBQrO
Oxaenediynes through the Nicholas-Type #Macrocyclization Approach from @BalovaGroup onlinelibrary.wiley.com/doi/10.1002/ej…
Explore how #macrocyclization enhances #kinaseinhibitors, improving selectivity, overcoming resistance, and optimizing #druglikeproperties. Read More: amm-journal.org/index.php/2025… #Macrocyclizationstrategy #Drugdesign #Bindingaffinity #Kinaseselectivity @Science_Open @NUSingapore
Explore the potential of #nitriles 🧪 in #macrocyclization and #bioconjugation with the latest research by @NitscheLab. The game-changing cyanopyridine–aminothiol click reaction enables selective and biocompatible peptide/protein modifications 💪 👉 brnw.ch/21wLKXA
One-Step Catalyst-Transfer Macrocyclization: Expanding the Chemical Space of Azaparacyclophanes | Journal of the American Chemical Society @BonifaziGroup @univienna #Catalyst #Macrocyclization #Azaparacyclophanes pubs.acs.org/doi/10.1021/ja…
Researchers @Fudan University 🇨🇳 focus on #chemoenzymatic synthesis of macrocyclic peptides and polyketides via #thioesterase-catalyzed #macrocyclization. #biosynthesis ➡️ beilstein-journals.org/bjoc/articles/… Thanks for guest editing @LabRudolf, @barra_lena and Takayoshi Awakawa! 💎🔓 #BJOC
#Macrocyclization of Quinazoline-Based #EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR #L858R and #Del19 | Journal of Medicinal Chemistry pubs.acs.org/doi/abs/10.102…
pubs.acs.org
Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for...
Activating mutations in the epidermal growth factor receptor (EGFR) are frequent oncogenic drivers of non-small-cell lung cancer (NSCLC). The most frequent alterations in EGFR are short in-frame...
A new spotlight on #proximity-induced #one-pot #macrocyclization, where the required electrophile jumps out of the cleavage step: “It's happening like magic!” #peptidecyclization is like a piece of cake! Learn more from @AlexManicardi @GroupObcr pubs.acs.org/doi/10.1021/ac…
Stimuli-Responsive Macrocyclization Scaffold Allows In Situ Self-Assembly of Radioactive Tracers for Positron Emission Tomography Imaging of Enzyme Activity @njuniversity #Macrocyclization #Radioactive #Tracers #PET #Enzyme #PositronEmissionTomography pubs.acs.org/doi/10.1021/ja…
pubs.acs.org
Stimuli-Responsive Macrocyclization Scaffold Allows In Situ Self-Assembly of Radioactive Tracers...
Target-enabled bioorthogonal reaction and self-assembly of a small-molecule probe into supramolecules have shown promise for molecular imaging. In this paper, we report a new stimuli-responsive...
Online NOW | @J_A_C_S Rapid #Arene #Triazene Chemistry for #Macrocyclization. This strategy should find application in various fields of chemical biology, selective drug delivery, and identification of cyclic peptide hits after library screening. pubs.acs.org/doi/10.1021/ja…
🔥 New advance article for RSC Chemical Biology! 🔥 Joshua Price @BYU et al exploring "Long-range #PEG stapling: #macrocyclization for increased protein conformational stability and resistance to #proteolysis" 🧐 Get the full #openaccess story here 👉 ow.ly/WIkz50B3l7P
✳️ Gellman and co-authors report a foldamer-catalyzed #macrocyclization of dialdehydes to form 14- to 22-membered rings. ✨ This method can be used as the key step in a total synthesis of robustol! ✨ Great work! 👏 👉 fal.cn/381Tx
✳️Great Progress in Peptide Chemistry from @MonikaRaj_lab❗👏 Monika Ray and co-workers describe a #stereoselective #macrocyclization of #peptides through click chemistry. Great job! Enjoy reading this #SYNFACT of the month❗👉✨fal.cn/37J1y✨
Last speaker for today at #FlowChemistry Asia conference: Prof. Shawn Collins from the Université de Montréal about #macrocyclization processes in #flow @SelectBio
Oxaenediynes through the Nicholas-Type #Macrocyclization Approach from @BalovaGroup onlinelibrary.wiley.com/doi/10.1002/ej…
Online NOW | @J_A_C_S Rapid #Arene #Triazene Chemistry for #Macrocyclization. This strategy should find application in various fields of chemical biology, selective drug delivery, and identification of cyclic peptide hits after library screening. pubs.acs.org/doi/10.1021/ja…
A new spotlight on #proximity-induced #one-pot #macrocyclization, where the required electrophile jumps out of the cleavage step: “It's happening like magic!” #peptidecyclization is like a piece of cake! Learn more from @AlexManicardi @GroupObcr pubs.acs.org/doi/10.1021/ac…
Explore how #macrocyclization enhances #kinaseinhibitors, improving selectivity, overcoming resistance, and optimizing #druglikeproperties. Read More: amm-journal.org/index.php/2025… #Macrocyclizationstrategy #Drugdesign #Bindingaffinity #Kinaseselectivity @Science_Open @NUSingapore
Last speaker for today at #FlowChemistry Asia conference: Prof. Shawn Collins from the Université de Montréal about #macrocyclization processes in #flow @SelectBio
✳️ Gellman and co-authors report a foldamer-catalyzed #macrocyclization of dialdehydes to form 14- to 22-membered rings. ✨ This method can be used as the key step in a total synthesis of robustol! ✨ Great work! 👏 👉 fal.cn/381Tx
Researchers @Fudan University 🇨🇳 focus on #chemoenzymatic synthesis of macrocyclic peptides and polyketides via #thioesterase-catalyzed #macrocyclization. #biosynthesis ➡️ beilstein-journals.org/bjoc/articles/… Thanks for guest editing @LabRudolf, @barra_lena and Takayoshi Awakawa! 💎🔓 #BJOC
🔥 New advance article for RSC Chemical Biology! 🔥 Joshua Price @BYU et al exploring "Long-range #PEG stapling: #macrocyclization for increased protein conformational stability and resistance to #proteolysis" 🧐 Get the full #openaccess story here 👉 ow.ly/WIkz50B3l7P
Explore the potential of #nitriles 🧪 in #macrocyclization and #bioconjugation with the latest research by @NitscheLab. The game-changing cyanopyridine–aminothiol click reaction enables selective and biocompatible peptide/protein modifications 💪 👉 brnw.ch/21wLKXA
✳️Great Progress in Peptide Chemistry from @MonikaRaj_lab❗👏 Monika Ray and co-workers describe a #stereoselective #macrocyclization of #peptides through click chemistry. Great job! Enjoy reading this #SYNFACT of the month❗👉✨fal.cn/37J1y✨
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