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RNA modulates hnRNPA1A amyloid formation mediated by biomolecular condensates. Congratulations @ChiaraMore97 and the team. @NatureChemistry, @ETH_DCHAB nature.com/articles/s4155…
The interface of hnRNPA1 LCD condensates promotes the transition to amyloids. Congratulations to our leading author, @M_Linsenmeier, and the fantastic team! @NatureChemistry @ETH_DCHAB nature.com/articles/s4155…
Appointed tenure at @ETH_en. I'm grateful to my inspiring mentors, current and former group members, colleagues and collaborators, for all the support, dedication and contributions along the way. Looking forward to the new exciting projects in front of us!
👏 Congratulations to 14 new profs appointed by the @ETH_Rat! @bernd_bickel @Cindy_brGDGT @AllardDuursma @AHarms485 @Chakothra @natalia_pikor Mikaela Iacobelli @ArosioLab_ETH Caroline Dorn @debocklab Andreas Fichtner @petra_schmid Hans Jakob Wörner @DS3Lab u.ethz.ch/e2KMT
Congratulations to @M_Linsenmeier and all others, @MariaHondele, Fulvio Grigolato, Eleonora Secchi, @KarstenWeisLab! LCDs and biochemical activity can keep condensates fluid-like and prevent aging into arrested states. @NatureComms nature.com/articles/s4146…
Another part of my PhD @ArosioLab_ETH out today in @NatureComms! We applied Differential Dynamic Microscopy to investigate the effect of LCDs, RNA & biochemical activity on condensate material properties & aging. nature.com/articles/s4146…
Work of @M_Linsenmeier showing that the interface of condensates of a disordered LCD promotes amyloid formation. Important connection with the beautiful work of @MinaFaragSci and @PappulabWashU, showing expanded conformations at the interface. biorxiv.org/content/10.110…
Another part of my PhD @ArosioLab_ETH out today in @NatureComms! We applied Differential Dynamic Microscopy to investigate the effect of LCDs, RNA & biochemical activity on condensate material properties & aging. nature.com/articles/s4146…
It is with pleasure to announce the DPCI PhD Student Award featuring rising stars in the field of Polymers, Colloids & Interfaces within Switzerland. Deadline: 1st of June Link: scg.ch/component/page… To our 16 followers: please retweet and share within your network!
Our work on polymer-based programmable liquid droplets led by Umberto @UCPalmiero has been featured on the front cover of Advanced Materials onlinelibrary.wiley.com/doi/full/10.10…
Congrats Umberto for the work on programmable liquid droplets based on associative zwitterionic polymers with "stickers-and-spacers" architecture, now out in Advanced Materials: onlinelibrary.wiley.com/doi/epdf/10.10…
Another part of my PhD @ArosioLab_ETH out today in @NatureComms! We applied Differential Dynamic Microscopy to investigate the effect of LCDs, RNA & biochemical activity on condensate material properties & aging. nature.com/articles/s4146…
our work led by Andi highlighted in @ChemSystemsChem !
This month's Reader's Choice is the article by @ArosioLab_ETH and co-workers on the acceleration of an enzymatic reaction in liquid phase separated compartments based on intrinsically disordered protein domains. Check it out!➡️bit.ly/3wst7RB
Our work on the binding of the small heat-shock protein αB-crystallin to α-synuclein fibrils and the entropic forces driving this process now published in @PNASNews. Congratulations, @scheidt_tom, Jackie, Carl, Matthias, Georg, Quentin, Therese and thanks to all the great ...
Two postdoc positions available in our lab! If you are interested in #protein #condensates and biochemical reactions/aggregation occurring within them, and/or in protein-protein interactions, feel free to contact us directly: arosiogroup.ethz.ch/the-group.html
Postdoc position available! Interested in #protein #condensates? Skills in X-ray and #neutron techniques? Join us to look at liquid-liquid phase separation in IDPs systems. @aelangkilde @cphsaxs Thanks to @novonordiskfond for funding the project! employment.ku.dk/all-vacancies/…
📢📢 Open assistant professorship @ETH_en on Digital Chemistry strongly supported by @NCCR_Catalysis. We look forward to your application! If questions arise, don't hesitate to get in touch with @catalysis_eth or @guillengosalbez jobs.sciencecareers.org/job/552465/ass…
Mimicking "stickers-and-spacers" protein LCDs with synthetic polymers. Towards programmable synthetic droplets for biotechnology (e.g. bioseparation). After a long effort happy to share the preprint of the work led by Umberto: chemrxiv.org/engage/chemrxi…
Our work on rapid characterisation and quantification of extracellular vesicles by microfluidics. Great collaboration within the @ves4us consortium, the Leroux group and the @RiveraChemLab. Congrats Carolina and thanks everybody! doi.org/10.1002/adhm.2…
Researchers develop a microfluidic device that uses multi-wavelength fluorescence detection to provide information on extracellular vesicle size, concentration, and composition. @ArosioLab_ETH @ETH_en @ETH_DCHAB Read the article: ow.ly/EvOm50F84xh
Work led by @M_Linsenmeier, great collaboration with @MariaHondele, @KarstenWeisLab, Eleonora Secchi, Fulvio Grigolato on DDM to analyse the material properties of condensates, showing the role of RNA and biochemical activity on liquidity and aging. disq.us/t/3v69lqy
Heterotypic interactions within biomolecular condensates could prevent the formation of amyloid fibrils, despite the local increase in protein concentration Congrats Andi! @ChemicalScience pubs.rsc.org/en/content/art…
What a day for our lab: successful defence of the first PhD student (congrats Marie!!) and award of an #ERCCoG grant in support of our research program on mimicking biological phase separation to develop adaptable compartments. Thrilled and very grateful to @ERC_Research.
📢 ERC Consolidator Grant results are out! 327 top researchers received #ERCCoG funding worth in total €655 million - to address frontier research questions, build up their teams & have far-reaching impact. The full story ➡️ bit.ly/2Lk1IxL 🇪🇺#EUfunded @GabrielMariya
Our recent work on kinetic fingerprints differentiating the mechanisms of action of anti-Amyloidβ antibodies published in @NatureSMB: nature.com/articles/s4159…
Thermodynamic and kinetic design principles for #amyloid-aggregation inhibitors published in @PNASNews by Thomas M and Georg M together with @SaricLab, @G_T_Heller, Samo Curk, @ArosioLab_ETH, Sara Linse, Chris Dobson and @mvendruscolo14: pnas.org/content/pnas/1…
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