Bálint Csörgő
@BCsorgo
Genome engineering, synthetic biology, experimental evolution enthusiast. Group leader @BiochemBrc, @SysbioS, former Post-doc @UCSF, @EMBL
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Happy to have contributed to this work, which reminds us to proceed with caution when relying on new antibiotics
The common bacterial pathogen #Saureus quickly evolves resistance to a range of experimental and recently approved #antibiotics, according to a new systems analysis that could inform future drug development efforts. @Csaba_Pal_Lab @SysbioS scim.ag/4gQmPBp
🚨 Excited to share that our new study, “ESKAPE pathogens rapidly develop resistance against antibiotics in development in vitro” is just published in @NatureMicrobiol. For details, see the 🧵below and read the paper here: nature.com/articles/s4156…
Thrilled to share our latest work, "Antibiotic candidates for Gram-positive bacterial infections induce multidrug resistance" in @ScienceTM! For details, see the thread below and read the paper here: science.org/doi/10.1126/sc…
📢 Thrilled to announce our latest research in @CellCellPress! We've created a global ‘superbug map’ for a critically antibiotic-resistant bacterium to inform #phagetherapy 🧵1/11 cell.com/cell/fulltext/…
Happy to have played a part in this project spearheaded by @SergeyVMelniko1 group, goes to show what kinds of exciting biology can be discovered by studying extremophiles!
Bacteria have an astonishing ability to put their life on pause in the face of stress and starvation by entering a state of dormancy. Here, we discover one aspect of this remarkable self-preservation strategy: nature.com/articles/s4158…
Years long hard work has finally borne fruit with our paper out in @NatureMicrobiol! We studied antibiotic resistance #AMR by employing engineered #phages to deliver large DNA libraries into clinical strains together with @ApjokGabor @SysbioS Read more: rdcu.be/c5j34
Excited to share our preprint on a crazy new anti-CRISPR mechanism: translation-dependent mRNA downregulation! biorxiv.org/content/10.110… Special thanks to all co-authors: Alexander Talaie, Heloise Carion, Yang Zhang, Sukrit Silas, @liyuping927 and @joeBondyDenomy!
1/4 We are excited to open our postdoc #fellowship call for applications between @embl & @StanfordMed or @StanfordHumSci to enable collaboration & international training. stan.md/LSAfellows Show us your idea for bridging two leading institutions! 📅27 Jan 2023
Amazing work by Viktória Lázár and @RoyKishony. This should be definitely the next item on your reading list. 🧐
Nature research paper: Antibiotic combinations reduce Staphylococcus aureus clearance go.nature.com/3CgJXG2
Our preprint @joeBondyDenomy on a newly discovered bacteria immune system against a group of nucleus-forming jumbophages is out (biorxiv.org/content/10.110…). We named this immune system “JUmbophage Killer” (Juk). 1/n
Very happy to announce I will be starting as a junior PI this fall @BiologicalRese1! Many many thanks to all of my colleagues and mentors in the labs of Gyorgy Posfai, @Csaba_Pal_Lab, @joeBondyDenomy, @LarsMSteinmetz who have helped me along the way!
We are thrilled to announce that two former postdocs @BCsorgo and Viktória Lázár return to the BRC and establish own research groups with the help of Lendület (Momentum) grants. Congratulations! mta.hu/mta_hirei/tize…
We have two jobs closing soon @embl! 👩🔬 #1 A bioinformatics postdoc to develop new analytical tools & inform experimental directions: embl.org/jobs/position/… 🧑💼#2 An enthusiastic programme manager for @LiSciAlliance. Diverse role with comms, strategy etc embl.org/jobs/position/…
Excited to share our latest work in @ScienceMagazine! The talented #Synbio duo @scalefreegan & Amanda Hughes explored the transcriptional consequences resulting from scrambling pieces of the genome & putting them back together in a random order... Excellent thread by Aaron👇
We are thrilled to announce that two former postdocs @BCsorgo and Viktória Lázár return to the BRC and establish own research groups with the help of Lendület (Momentum) grants. Congratulations! mta.hu/mta_hirei/tize…
Write up from new post-doc in the lab, @MozumdarDeepto, and former post-doc @BCsorgo on exciting new paper showing how to genetically manipulate tricky bacteria!
First Cut: "Genetic Manipulation of a CAST of Characters in a Microbial Community" -- Mozumdar, Csörgő, @joeBondyDenomy discuss the toolkit for precision gene editing in a bacterial community (recent @BanfieldJill @doudna_lab paper @NatureMicrobiol). liebertpub.com/doi/10.1089/cr…
Check out our seminar with Lina next Monday all about our work using Cas3 to edit bacteria!
Mon. March 22nd Bálint Csörgő, Lina León and Peter DeWeirdt - mailchi.mp/58df9040f64a/t…
Using Cas3 to make large deletions. #CRISPR @UCSF @BCsorgo @LinaMLion @joeBondyDenomy CRISPR Meets Pac-Man: New DNA Cut-and-Paste Tool Enables Bigger Gene Edits | UC San Francisco bit.ly/34n5Ow8
Recruiting bioinformaticians to work in the fields of genomics and evolution of antibiotic resistance, genome engineering and phage biology @ labs of Balázs Papp, @balint_kintses, hosted at @BiochemBrc and HCEMM, a partner institute of @EMBL, in Szeged. group.szbk.u-szeged.hu/sysbiol/data/p…
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