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CellRepMed's profile picture. Broad-scope #OA journal from @CellPressNews publishing cutting-edge science across the spectrum of #Translational and #ClinicalResearch | Editor: @DrSaraHam

Cell Reports Medicine

@CellRepMed

Broad-scope #OA journal from @CellPressNews publishing cutting-edge science across the spectrum of #Translational and #ClinicalResearch | Editor: @DrSaraHam

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Cell Reports Medicine
 @CellRepMed
Nov 19

On the Cover: A gardener removes weeds among flowers—just like therapies targeting the tumour microenvironment can eliminate cancer cells while sparing healthy ones. Dive into our special issue for expert reviews on immune cell targeting in cancer! Artwork by Justine Reimand.

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Cell Reports Medicine
 @CellRepMed
Nov 26

Online now: Multi-center benchmarking of large language models for clinical decision support in lung cancer screening dlvr.it/TPTmQF

CellRepMed's tweet card. Duan et al. benchmark six large language models using multi-center real-world LDCT reports for lung cancer screening. GPT-4 leads in accuracy, while Claude 3 Opus excels in readability. Exploratory...
Multi-center benchmarking of large language models for clinical decision support in lung cancer...
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 26

Online now: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis dlvr.it/TPTTWH

CellRepMed's tweet card. Yao et al. identify that IL-17C in peritoneal fluid drives endometriosis-associated carcinogenesis via IL-17RE/PI3K-mediated EMT. They demonstrate that blocking IL-17C-IL-17RE signaling suppresses...
Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 25

Online now: Nonsense-mediated mRNA decay inhibits TRAF6-dependent anti-tumor immunity in colorectal cancer dlvr.it/TPSkHJ

CellRepMed's tweet card. Wang et al. demonstrate that nonsense-mediated mRNA decay (NMD) is abnormally activated in CRC. Inhibiting NMD remodels the tumor microenvironment by activating the TRAF6-TBK1 axis and boosting CD8+...
Nonsense-mediated mRNA decay inhibits TRAF6-dependent anti-tumor immunity in colorectal cancer
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 25

Online now: Ngn2 and Isl1-mediated astrocyte-to-neuron conversion in vivo promotes functional recovery after spinal cord injury dlvr.it/TPSRvD

CellRepMed's tweet card. Zhou et al. show that activation of Ngn2 and Isl1 enabled reactive astrocytes to convert into neurons, which promotes functional recovery after spinal cord injury, with new neurons forming synaptic...
Ngn2 and Isl1-mediated astrocyte-to-neuron conversion in vivo promotes functional recovery after...
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 24

Online now: Precision prediction of venetoclax-azacitidine treatment efficacy in acute myeloid leukemia via integrative drug screening and machine learning dlvr.it/TPRjRd

CellRepMed's tweet card. Jin et al. integrate drug sensitivity testing, transcriptomics, and functional assays to uncover key determinants of venetoclax-azacitidine (VEN/AZA) response in AML. They develop an eight-gene model...
Precision prediction of venetoclax-azacitidine treatment efficacy in acute myeloid leukemia via...
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 24

Online now: Unlocking the tumor microenvironment: Innovative strategies for cancer therapy and translational insights dlvr.it/TPRMyM

CellRepMed's tweet card. The tumor microenvironment (TME) is a highly complex and dynamic ecosystem composed of diverse cellular and extracellular components that critically influence cancer initiation, progression, and...
Unlocking the tumor microenvironment: Innovative strategies for cancer therapy and translational...
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 22

Online now: From visualization to prediction: Dissecting metabolic heterogeneity with DDRTree dlvr.it/TPPt42

CellRepMed's tweet card. The discriminative dimensionality reduction tree (DDRTree) framework provides a powerful approach to unravel metabolic heterogeneity and delineate clinically relevant subtypes. In this issue, Qiu et...
From visualization to prediction: Dissecting metabolic heterogeneity with DDRTree
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 21

Online now: System analysis links SMARCD3 regulons to growth signaling and MEK inhibitor response in everolimus-resistant ER+ breast cancer cells dlvr.it/TPP0Ps

CellRepMed's tweet card. Everolimus is approved for treating advanced ER+ breast cancers, yet many patients develop resistance. Medina et al. identify SMARCD3 regulons linked to activation of alternate growth-factor signal...
System analysis links SMARCD3 regulons to growth signaling and MEK inhibitor response in everolim...
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 20

Discuss your gene and cell therapy research with editors from Cell Stem Cell and Cell Reports Medicine. Talk about your work and discover the best place to submit, what will help to get your work published, and what you can expect when you submit. hubs.li/Q03V9Yb50

CellRepMed's tweet image. Discuss your gene and cell therapy research with editors from Cell Stem Cell and Cell Reports Medicine. Talk about your work and discover the best place to submit, what will help to get your work published, and what you can expect when you submit. hubs.li/Q03V9Yb50
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Cell Reports Medicine
 @CellRepMed
Nov 20

Online now: A prognostic index integrating deep learning baseline PET/CT biomarkers and multi-omics profiling in diffuse large B cell lymphoma dlvr.it/TPMw6S

CellRepMed's tweet card. Wang et al. develop a clinical-imaging-multi-omics prognostic index for diffuse large B cell lymphoma by integrating quantitative PET/CT biomarkers, genetic subtypes, and clinical risk factors. By...
A prognostic index integrating deep learning baseline PET/CT biomarkers and multi-omics profiling...
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 20

Together with our partners @ZJU_China, Liangzhu Laboratory, we're thrilled to announce @CellSymposia Taking programmed cell death from mechanisms to interventions 📍Hangzhou, China 📆October 22–24, 2026 Visit our website: hubs.li/Q03TKyCn0 #CSCellDeath26

CellRepMed's tweet image. Together with our partners @ZJU_China, Liangzhu Laboratory, we're thrilled to announce @CellSymposia Taking programmed cell death from mechanisms to interventions 📍Hangzhou, China 📆October 22–24, 2026 Visit our website: hubs.li/Q03TKyCn0 #CSCellDeath26
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Cell Reports Medicine
 @CellRepMed
Nov 19

Online now: Virus envelope glycoprotein targeting bispecific T cell engager protects mice from lethal severe fever with thrombocytopenia virus infection dlvr.it/TPMFgs

CellRepMed's tweet card. Peng et al. reveal that the impaired cytotoxicity and exhausted state of T cells are significantly associated with lethal outcomes in SFTS patients and demonstrate that Gn-targeted bispecific T cell...
Virus envelope glycoprotein targeting bispecific T cell engager protects mice from lethal severe...
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 19

Online now: Maternal diabetes programs sexually dimorphic early-onset cardiovascular dysfunction in metabolically healthy offspring dlvr.it/TPLxth

CellRepMed's tweet card. Zhao et al. translationally demonstrate how maternal diabetes induces early-onset endothelial dysfunction in sons, but not daughters, even when offspring are metabolically healthy. This challenges...
Maternal diabetes programs sexually dimorphic early-onset cardiovascular dysfunction in metabolic...
Source: cell.com
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Cell Reports Medicine
 @CellRepMed
Nov 18

Online now: Plasma proteomics identifies proteins and pathways associated with incident epilepsy dlvr.it/TPKsFw

CellRepMed's tweet card. Zhang et al. utilize large-scale plasma proteomic data to investigate the association between 2,920 plasma proteins and the risk of incident epilepsy. They characterize the temporal trajectories of...
Plasma proteomics identifies proteins and pathways associated with incident epilepsy
Source: cell.com
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