CheesemakerMD's profile picture. INR/Clinician scientist @inselgruppe @ScanNeuroradBE  | Neurovascular Research Team  | Stroke

Johannes Kaesmacher

@CheesemakerMD

INR/Clinician scientist @inselgruppe @ScanNeuroradBE | Neurovascular Research Team | Stroke

Johannes Kaesmacher أعاد

This topical review by Campbell et al. discusses the optimization of #stroke reperfusion trials, key imaging research priorities, and improved definitions for macro vs microvascular reperfusion. ahajournals.org/doi/full/10.11… @GeorgeHarston @PoojaKhatriMD @FishingNeurons @NguyenThanhMD

StrokeAHA_ASA's tweet image. This topical review by Campbell et al. discusses the optimization of #stroke reperfusion trials, key imaging research priorities, and improved definitions for macro vs microvascular reperfusion. ahajournals.org/doi/full/10.11…

@GeorgeHarston @PoojaKhatriMD @FishingNeurons @NguyenThanhMD

Johannes Kaesmacher أعاد

Presented at #SVIN25: CREST-2: In high-grade asymptomatic carotid stenosis, addition of stenting to medical therapy led to a lower risk of stroke over a 4-year period. Endarterectomy did not lead to a significant benefit. Full results: nej.md/3LK9kst Editorial:…

NEJM's tweet image. Presented at #SVIN25:

CREST-2: In high-grade asymptomatic carotid stenosis, addition of stenting to medical therapy led to a lower risk of stroke over a 4-year period. Endarterectomy did not lead to a significant benefit. Full results: nej.md/3LK9kst 

Editorial:…

Johannes Kaesmacher أعاد

🧠Study of patients who underwent intracranial stenting after EVT found no differences between those with vs. without IVT in: 🗓️90-day mRS shift 🗓️90-day mortality 🕐 24h sICH rates Read more here👇 journals.sagepub.com/doi/abs/10.117…

IntJStroke's tweet image. 🧠Study of patients who underwent intracranial stenting after EVT found no differences between those with vs. without IVT in:

🗓️90-day mRS shift
🗓️90-day mortality
🕐 24h sICH rates

Read more here👇
journals.sagepub.com/doi/abs/10.117…

Johannes Kaesmacher أعاد

Excelente oportunidade e grande iniciativa!! 👏👏👏 @sheilambrasil @FishingNeurons

📣 Calling all stroke specialists in Latin America! Join us in São Paulo, Dec 2–5 2025, for the first Latin America Stroke Summer School from University of Bern in partnership with Rede Brasil AVC and ESO, endorsed by WSO. 🎥 Check out Urs Fischer’s invitation and get ready for…



Johannes Kaesmacher أعاد

The DO-IT study is gaining momentum in Europe, and Canada is next! 🇨🇦 Are you ready to DO IT? 👍💪💉

🔊 Exciting DO-IT Trial Update!🔊 📈 🌍 The trial continues to expand, with 24 sites actively recruiting across Europe and 33 patients enrolled so far! - 27 in🇨🇭 - 3 in the 🇳🇱 - 2 in 🇧🇪 - 1 in 🇪🇸 👏 A big thank you to everyone contributing! 💉🧑‍⚕️Recruit. Care. Cure. DO-IT!

DOIT_trial's tweet image. 🔊 Exciting DO-IT Trial Update!🔊
📈 🌍 The trial continues to expand, with 24 sites actively recruiting across Europe and 33 patients enrolled so far!
- 27 in🇨🇭
- 3 in the 🇳🇱
- 2 in 🇧🇪
- 1 in 🇪🇸
👏 A big thank you to everyone contributing!
💉🧑‍⚕️Recruit. Care. Cure. DO-IT!


Johannes Kaesmacher أعاد

In patients with chronic coronary syndrome taking oral anticoagulants, adding aspirin led to higher risks of cardiovascular events, major bleeding, and death from any cause than anticoagulation alone. DO NOT ADD ASS TO (D)OAC for chronic CAD nejm.org/do/10.1056/NEJ…

Original Article: Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation (AQUATIC trial) nej.md/45AU4Wp #Cardiology

NEJM's tweet image. Original Article: Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation (AQUATIC trial) nej.md/45AU4Wp 

#Cardiology


Johannes Kaesmacher أعاد

🔊 Exciting DO-IT Trial Update!🔊 📈 🌍 The trial continues to expand, with 24 sites actively recruiting across Europe and 33 patients enrolled so far! - 27 in🇨🇭 - 3 in the 🇳🇱 - 2 in 🇧🇪 - 1 in 🇪🇸 👏 A big thank you to everyone contributing! 💉🧑‍⚕️Recruit. Care. Cure. DO-IT!

DOIT_trial's tweet image. 🔊 Exciting DO-IT Trial Update!🔊
📈 🌍 The trial continues to expand, with 24 sites actively recruiting across Europe and 33 patients enrolled so far!
- 27 in🇨🇭
- 3 in the 🇳🇱
- 2 in 🇧🇪
- 1 in 🇪🇸
👏 A big thank you to everyone contributing!
💉🧑‍⚕️Recruit. Care. Cure. DO-IT!

Johannes Kaesmacher أعاد

DETECT🩸🧠✨️ neurology.org/doi/10.1212/WN…


Johannes Kaesmacher أعاد

Cancer-related strokes are difficult to manage, synonym of bad prognosis and still poorly understood, which is why I did my clinical PhD on this exciting topic. It is now published online, check it out!😉: boristheses.unibe.ch/6822 @StrokeBern @MedFacultyUniBE

Morin_Beyeler's tweet image. Cancer-related strokes are difficult to manage, synonym of bad prognosis and still poorly understood, which is why I did my clinical PhD on this exciting topic. 
It is now published online, check it out!😉: boristheses.unibe.ch/6822
@StrokeBern @MedFacultyUniBE

Johannes Kaesmacher أعاد

Excited to see our work "SWICH - a fully automated deep learning model for CT-based ICH segmentation" presented by @bmsiepen at the World Stroke Conference 2025 in Barcelona! 🎉 Open-access software available - contact our team to collaborate or try it out. #WSC2025

StrokeBern's tweet image. Excited to see our work "SWICH - a fully automated deep learning model for CT-based ICH segmentation" presented by @bmsiepen at the World Stroke Conference 2025 in Barcelona! 🎉

Open-access software available - contact our team to collaborate or try it out.
#WSC2025
StrokeBern's tweet image. Excited to see our work "SWICH - a fully automated deep learning model for CT-based ICH segmentation" presented by @bmsiepen at the World Stroke Conference 2025 in Barcelona! 🎉

Open-access software available - contact our team to collaborate or try it out.
#WSC2025
StrokeBern's tweet image. Excited to see our work "SWICH - a fully automated deep learning model for CT-based ICH segmentation" presented by @bmsiepen at the World Stroke Conference 2025 in Barcelona! 🎉

Open-access software available - contact our team to collaborate or try it out.
#WSC2025
StrokeBern's tweet image. Excited to see our work "SWICH - a fully automated deep learning model for CT-based ICH segmentation" presented by @bmsiepen at the World Stroke Conference 2025 in Barcelona! 🎉

Open-access software available - contact our team to collaborate or try it out.
#WSC2025

Johannes Kaesmacher أعاد

🚨new paper! Should stroke patients with tandem lesions undergo stenting during EVT? And does prior IVT matter? Find out below 👇 ahajournals.org/doi/10.1161/ST… #stroke @manonkappelhof @kiliantreurniet @CheesemakerMD @FishingNeurons


Johannes Kaesmacher أعاد

Please apply

📢 Postdoc opening working with routine health data and clinical trial data in Bern, Switzerland. The candidate should also have interest in meta-research. See jobs.apps.be.ch/job-vacancies/…



Johannes Kaesmacher أعاد

This graph sums it up. In acute stroke with tandem lesions (ICA + intracranial occlusion), acute carotid stenting during EVT was associated with better 90-day outcomes than EVT without stenting. Outcomes were similar with or without prior IV thrombolysis (IVT). Caveat:…

whitfieldlewis6's tweet image. This graph sums it up. In acute stroke with tandem lesions (ICA + intracranial occlusion), acute carotid stenting during EVT was associated with better 90-day outcomes than EVT without stenting.

Outcomes were similar with or without prior IV thrombolysis (IVT).

Caveat:…

Acute Carotid Stenting for Tandem Lesions in Patients Randomized to Endovascular Treatment With or Without Thrombolysis: Results From the IRIS Individual Participant Data Meta-Analysis | Stroke ahajournals.org/doi/10.1161/ST…



Johannes Kaesmacher أعاد

Disappointing negative outcome from the THEIA trial of IV alteplase vs aspirin in CRAO, albeit underpowered. Similar outcomes reported at ESOC 2025 in the yet published TenCRAOS trial of IV tenecteplase. Is intra-arterial thrombolysis the answer here? 🤔 thelancet.com/journals/laneu…


Johannes Kaesmacher أعاد

🚨Exciting DO-IT Trial Update!🚨 Co-funding has been granted from PHRC-N for France. A big thank you to Guillaume Turc and their teams for this great accomplishment.


Johannes Kaesmacher أعاد

Acute Carotid Stenting for Tandem Lesions in Patients Randomized to Endovascular Treatment With or Without Thrombolysis: Results From the IRIS Individual Participant Data Meta-Analysis | Stroke ahajournals.org/doi/10.1161/ST…


Johannes Kaesmacher أعاد

The October episode of the #StrokeAlert Podcast is now available. Host @NAsdaghi highlights articles in the Oct. issue of #Stroke and interviews @TotoMynell on "Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants." ahajournals.org/do/10.1161/pod…

StrokeAHA_ASA's tweet image. The October episode of the #StrokeAlert Podcast is now available. Host @NAsdaghi highlights articles in the Oct. issue of #Stroke and interviews @TotoMynell on "Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants." ahajournals.org/do/10.1161/pod…

Johannes Kaesmacher أعاد

✨September was a busy and successful month for the @DOIT_trial ✨Another 3 centers are now active and recruiting.🎉 Thank you to the trial teams in Valladolid, Leuven, and Schleswig! We are thrilled to have you on board and welcome you to the @DOIT_trial and community.

DOIT_trial's tweet image. ✨September was a busy and successful month for the @DOIT_trial ✨Another 3 centers are now active and recruiting.🎉
Thank you to the trial teams in Valladolid, Leuven, and Schleswig! We are thrilled to have you on board and welcome you to the @DOIT_trial and community.
DOIT_trial's tweet image. ✨September was a busy and successful month for the @DOIT_trial ✨Another 3 centers are now active and recruiting.🎉
Thank you to the trial teams in Valladolid, Leuven, and Schleswig! We are thrilled to have you on board and welcome you to the @DOIT_trial and community.
DOIT_trial's tweet image. ✨September was a busy and successful month for the @DOIT_trial ✨Another 3 centers are now active and recruiting.🎉
Thank you to the trial teams in Valladolid, Leuven, and Schleswig! We are thrilled to have you on board and welcome you to the @DOIT_trial and community.

Johannes Kaesmacher أعاد

Bridging thrombolysis with tenecteplase versus endovascular thrombectomy alone for large-vessel anterior circulation stroke: a target trial emulation analysis jnnp.bmj.com/content/early/…


Johannes Kaesmacher أعاد

In anterior circulation stroke patients post-thrombectomy, low and medium doses of intra-arterial tenecteplase demonstrated adequate safety to warrant larger trials to investigate their therapeutic potential. ja.ma/47ZpZBx

JAMANeuro's tweet image. In anterior circulation stroke patients post-thrombectomy, low and medium doses of intra-arterial tenecteplase demonstrated adequate safety to warrant larger trials to investigate their therapeutic potential. ja.ma/47ZpZBx

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