David Gate
@DGateLab
Director, Abrams Research Center, Northwestern Neurology. The Gate lab studies the immune system in neurodegenerative diseases.
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Key to research success: ambition in vision, but pragmatism in execution. You must be guided by a long-term, ambitious goal that addresses a fundamental problem, rather than chasing incremental gains on established benchmarks. Yet, your progress should be grounded by tractable…
We are proud to announce a collaboration with @ARC_Neuro at Northwestern University Feinberg School of Medicine to harness AI for rapid discovery and innovation in Alzheimer’s disease research. Using Lens, the Center and Tempus teams will work together to uncover genomic patterns…
I am excited to present our new study out in @NatureMedicine where we discover a novel synaptic protein biomarker to predict if and when someone will get Alzheimer’s disease dementia. Part 2/3 from my PhD work in the @wysscoray lab. 🧵1/12 Full study 🔗: nature.com/articles/s4159…
The Gate lab is fortunate to have such a talented scientist like @TerryRSuk joining us soon. Check out his impressive work!
We’re happy to share that our labs first #ALS and #FTD study “A stress-dependent TDP-43 SUMOylation program preserves neuronal function” is now online @MolNeuro! doi.org/10.1186/s13024…
In brains of people immunized against Aβ, postmortem omics reveal microglial plaque clearing pathways. @NorthwesternU ow.ly/3cOl50VitbY
It’s quite an experience to have some of your favorite labs like @TheColonnaLab and @Haass_Lab comment on your lab’s research. Great reporting by Alzforum! alzforum.org/news/research-…
This Northwestern Breakthroughs podcast nicely encapsulates our study. The host does a great job leading the discussion for the lay audience to digest our work. I hope this allows people to better understand the results and impact of this study. youtu.be/bZrdwGQ_Ok0
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YouTube
How Alzheimer's Drugs Work with David Gate, PhD
This video describes the findings from our recent study conducted at @ARC_Neuro. In the video, lead author @LynnOlst and I discuss the findings and their implications for Alzheimer’s disease. youtu.be/pnRzktJRWAo
youtube.com
YouTube
Treatment for Alzheimer’s may lie in the brain’s own cleanup crew
Excited to share our latest @NatureMedicine study from our new center @ARC_Neuro! 🧠✨ Using spatial transcriptomics & scRNA-seq, we uncover how Aβ-targeting immunotherapies shape microglial responses in AD patient brains. A thread with our key findings is below! 🧵(1/15)
Spatial transcriptomics reveals distinct microglial mechanisms driving amyloid-β clearance in both passive and actively immunized #Alzheimer’s disease patients @NUFeinbergMed nature.com/articles/s4159…
More excellent work from the brilliant @LynnOlst. I’m a very proud PI today. More to come from @ARC_Neuro!
Excited to share our latest @NatureMedicine study from our new center @ARC_Neuro! 🧠✨ Using spatial transcriptomics & scRNA-seq, we uncover how Aβ-targeting immunotherapies shape microglial responses in AD patient brains. A thread with our key findings is below! 🧵(1/15)
Excited to announce that we are recruiting at our new Neurogenomics Center at Northwestern! We are looking for passionate postdoc candidates to join our team. nature.com/naturecareers/…
The team at Abrams Research Center on Neurogenomics, led by @DGateLab, is excited to explore their new lab! Using #ArtificialIntelligence, genetic research and global collaborations, they’re advancing Alzheimer’s disease research. #NMBetter
I’m proud to have contributed (slightly) to this tour de force by @ElisaFlo04
Our December issue, featuring a Focus on Single Cell Genomics, is now live! nature.com/neuro/volumes/…
Our December issue, featuring a Focus on Single Cell Genomics, is now live! nature.com/neuro/volumes/…
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