Extracellular Matrix News
@ExtracellMatrix
An online resource for the extracellular matrix and tissue engineering research community. Part of the @STEMCELLTech Science News service.
قد يعجبك
🥼 Science News by @STEMCELLTech can help you stay on top of the latest cell biology research! 💌 Our website and newsletters keep scientists current with the latest peer-reviewed research, as well as industry and policy news. Learn more 👉 //bit.ly/3Xn6mwV
Drs. Georgia Squyres and Dianne Newman at @Caltech reveal how the architecture of extracellular DNA in the biofilm matrix is controlled by single-cell lysis during Pseudomonas aeruginosa biofilm development. @PNASNews | bit.ly/4n7Enve
🧫 Tissue engineering (TE) fundamentals were applied to mimic the bone ECM and cells' microenvironment. These findings demonstrate the potential of chitosan/MβCHNC biomaterial for TE as alveolar bone regeneration. 👉 bit.ly/4napgB3
This study investigated the anti-fibrotic potential of celecoxib, a selective cyclooxygenase-2 inhibitor, and elucidated its underlying mechanisms. Check it out!👉 bit.ly/473vwpP
🔬 This study out of @KingsCollegeLon shows that fibronectin stimulates human VSMCs to secrete small extracellular vesicles by activating the β1 integrin/FAK/Src pathway as well as Arp2/3-dependent branching of the actin cytoskeleton. @eLife | bit.ly/3WsD2US
This study from @KingsCollegeLon shows that fibronectin stimulates human vascular smooth muscle cells to secrete small extracellular vesicles by activating the β1 integrin/FAK/Src pathway and Arp2/3-dependent branching of the actin cytoskeleton. @eLife | bit.ly/3WsD2US
🔬 Investigators assessed the potential mechanisms of an enriched Vitis vinifera in mediating mineralization using both constituted type-1 #collagen scaffolds and dentin matrix substrate. 🦷 bit.ly/4mRjNPz
🧫 Scientists used electrospun matrices to culture Jurkat T-cells and observed that the cells remain entrapped in these matrices, facilitating their growth and clustering, which are the key phenomena for their activation and expansion. 🔗 rsc.li/42yYStr
🧫 Investigators explored nine post-translational modifications—methylation, acetylation, SUMOylation, Neddylation, phosphorylation, crotonylation, glycosylation, lactylation, and ubiquitination—each implicated in the pathogenesis of hepatic fibrosis. 👉 bit.ly/4oddhE5
🥼 Investigators used proteomic and phenotypic analyses to compare human dermal fibroblasts, dental pulp stem cells, and adipose-derived mesenchymal stem cells in terms of morphology, cell surface markers, differentiation, and proteomic profile. 🔗 bit.ly/3IHUHVr
🦴 JAK2-mutated myeloproliferative neoplasms exhibit an intrinsic activation of IFN-γ signaling associated with changes in the bone marrow TME and patients’ outcome. @LeukemiaJnl | go.nature.com/46IN3n3
🧫 Researchers investigated differences in ECM production and mechanical performance of tissue-engineered vascular grafts cultured with placental mesenchymal stem cells and smooth muscle cells in static and dynamic conditions. @BiomaterialsAdv | bit.ly/42Z4qNM
👇 Check this one out! 🦷 Scientists focused on the pathological changes of the gingival connective tissues from diabetic periodontitis and identified the ECM pathway as the key regulatory pathway. 👓 bit.ly/4nzO72q
💪 Emily Roloson and scientists at @hseas further the understanding of the role of tissue mechanical properties in directing muscle cell function and provide a tool for guiding specific behaviors necessary for muscle regeneration. 🔗 bit.ly/4muD89f
🧫 Researchers optimize a method for complete decellularization of rat esophagus and to solubilize the decellularized extracellular matrix proteins to evaluate in vitro properties for scaffold fabrication. 🥼 bit.ly/4mIDUzA
🔬 Investigators leveraged RNA-seq data to predict tumor matrix stiffness, aiming to reveal mechanical properties by molecular signatures across various cancer types. @IntJCanc | bit.ly/3KDzHzv
🧫 This review evaluates hydrogels as ECM mimics for 3D cell cultures, revisiting key ECM properties to replicate and summarize the impact of biochemical, structural, and mechanical features on cell behavior. 👉 @BioMaterSci | rsc.li/4mAcQSX
💪 This study furthered the understanding of the role of tissue mechanical properties in directing muscle cell function and provided a tool for guiding specific behaviors necessary for muscle regeneration. 👉 bit.ly/4muD89f
🐟 Researchers demonstrate that Leucine could promote #collagen deposition by inhibiting autophagy, providing novel insights into the mechanism underlying amino acid-regulated protein metabolism in vertebrates. 🔗 bit.ly/46D86WF
📊 Researchers utilized single-cell RNA sequencing, spatial transcriptomics, and a combination of in vivo and in vitro models to decode the dynamics of tumor-stroma interactions during human #LUAD progression. @oncogenejournal | go.nature.com/4mz6d3k
United States الاتجاهات
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قد يعجبك
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ASMB
@amsocmatbio -
Alberto Elosegui-Artola
@AEloseguiArtola -
BSMB
@BSMB1 -
Xavier Trepat
@XavierTrepat -
Renato V. Iozzo, MD PhD (Honoris causa)
@iozzo_v -
Thomas R. Cox
@thomasrcox -
Gordana Vunjak-Novakovic
@GVNlab -
Muscle Cell News
@musclecellnews -
The Extracellular Matrix Pharmacology Congress
@ecmcongress -
Liliana Schaefer, MD
@AJPCellPhysEIC -
Hematopoiesis News
@Hema_News -
Madeleine Oudin
@MadeleineOudin -
Intestinal Cell News
@Intestinal_Cell -
Joan Chang
@tranejoan -
Jon Humphries
@JDHL18
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