Intestinal Cell News
@Intestinal_Cell
An online resource for intestinal cell researchers. Part of the @STEMCELLTech Science News service.
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Stay current on colorectal cancer, IBD, and #colitis research. 💡 Intestinal Cell News delivers weekly #intestinal research highlights straight to your inbox. 🔔 Subscribe for free: bit.ly/4kkWMEu
Scientists establish CLK2 as a critical inhibitor of ferroptosis via the KEAP1/NRF2/HMOX1 and p53/SLC7A11 axes, supporting its potential as a therapeutic target for #colorectal cancer. 🔗 More in @CR_AACR: bit.ly/3L7y8dv
💌 Simplify your job search with Science News by @STEMCELLTech! Our website and regular newsletters keep scientists current with the latest peer-reviewed research, reviews, and job opportunities. 🔗 Learn more: bit.ly/48kdXmk
📖 This review examines the design, fabrication, and application of biomimetic nanocarriers specifically for colorectal cancer. It further explores the application of these nanocarriers in chemotherapy, #immunotherapy, gene therapy, and more! 🔗 bit.ly/4qkhtUk
😲 Check out Chagosendine C, a novel colorectal cancer treatment strategy, which shows strong antitumor activity and potential to overcome oxaliplatin resistance, with promising clinical prospects. @J_A_C_S | bit.ly/48wyBQj
💡 Researchers established a robust and stable 3DP-gastric cancer model and performed histopathological and genomic validation to find that the model well preserved the expression abundance and mutation profiles of markers in the parental tumors. 👉 bit.ly/3W9A9Ix
🥼 Scientists at @Inserm summarize recent studies on the roles of T3 and thyroid hormone nuclear receptor α1 in colon physiopathology, with an emphasis on epithelial/stromal or tumor/stromal interactions via cell-cell signaling. @cddpress | go.nature.com/477wH6m
Dr. Masakazu Yashiro led this study showing that thrombospondin-4 from cancer-associated fibroblasts downregulates ERBB2 expression in #GastricCancer cells. ✅ Check out the article to learn more! bit.ly/4h71FA0
In a recent @cddpress study, scientists confirmed that SNRPB is overexpressed in #GastricCancer and that this overexpression is associated with poor prognosis. 💡 Learn more: go.nature.com/3J5HLZB
🦠 Helicobacter pylori-induced aberrant methylation of ID4 mediated by DNMT3B drives #GastricCancer progression via DEC1-SHH signaling pathway, reported Shandong First Medical University scientists and their team. go.nature.com/46ZY2qQ
🔎 Scientists suggest that disrupting the dipeptidase 1–NKp30 interaction in colon cancer cells may enhance NK cell-mediated cytotoxicity. go.nature.com/3Wf8aY5
Automate your research where possible. Automated solutions will help you free up your time for other tasks and reduce user variability in experiments. @STEMCELLTech bit.ly/3VwQCpN
🧪 Researchers report that crotonate enhances intestinal regeneration after injury via HBO1-mediated H3K14 crotonylation. @naturecomms | go.nature.com/4h1AfeQ
🧪 A targeted liposomal garcinol formulation was developed by using the VRPMPLQ-NC16 peptide to target colon tumors. 👉 bit.ly/3VPwnns
💉 Researchers found that the absence of USP10 enhances chemotherapy sensitivity in colorectal cancer cells, providing a potential strategy for overcoming chemotherapy resistance and improving therapeutic outcomes. @oncogenejournal | go.nature.com/4gUPUfZ
🧫 Using colorectal cancer (CRC) #organoid models, researchers demonstrated that mechanical interactions with collagen I, a main constituent of the interstitial matrix, instruct the reprogramming of CRC cells. @UMCU_Intl | bit.ly/4mAUHEy
🧬 Researchers found that TRIM21 could influence tumor development and chemosensitivity to replication inhibitors by regulating DNA replication through the TCF3/MCM2/5 axis, suggesting a promising potential for CRC in the clinic. @cddpress | go.nature.com/3Iyfc6X
🍎 Investigators demonstrated that a decline in structural intestinal tissue homeostasis is associated with a decline in stem cell activity that can be counteracted by intermittent fasting. @MedUni_Wien | bit.ly/3VDs3aS
🥼 Researchers at the @KendraCarmonLab showed that cetuximab increased LGR5 protein levels and enhanced the efficacy of LGR5-targeted antibody-drug conjugates in several LGR5-expressing preclinical models of CRC. bit.ly/46FlvNQ
🧪 The @GloerichLab recently demonstrated that mechanical interactions with collagen I, a main constituent of the interstitial matrix, instruct the reprogramming of #ColorectalCancer cells. @CellReports | bit.ly/4mAUHEy
Researchers show that GPR15 differentially regulates the effects of cigarette smoke exposure on Crohn’s disease and ulcerative colitis. 🚬 🔓 Full details in @sigtrans_sttt: go.nature.com/3VWdEXd
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