Freeman Lab
@FreemanLabOMRF
Neuroepigenetics lab examining brain and retinal aging
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Study brain aging? Using a tamoxifen inducible cre model and want to TAM treat at an old age? Should work great. Check out our validation study: pubmed.ncbi.nlm.nih.gov/38058312/
Our new work examining cell type-specific DNA modification patterns in the brain demonstrates the importance of differentiating between mC and hmC in neuroepigenomic analyses. …eneticsandchromatin.biomedcentral.com/articles/10.11…
Check out our new work in conjunction #OcanasLab with on sex divergences in microglia phenotypes and senescence with aging. jneuroinflammation.biomedcentral.com/articles/10.11…
link.springer.com
Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocamp...
Journal of Neuroinflammation - Microglia, the brain’s principal immune cells, have been implicated in the pathogenesis of Alzheimer’s disease (AD), a condition shown to affect more...
Excited that our work on microglial MHC-I with aging and Alzheimer's is now published. Congratulations to Collyn Kellogg on his first paper as a 1st author! pubmed.ncbi.nlm.nih.gov/37393197/
NIA/NIH F99-K00 award for Victor Ansere from the FreemanLab @OMRF. This will support Victor's graduate work in plasma transfer treatments for aging and subsequent post-doc. Innovative award transition training award from @NIHAging. Congratulations to Victor!
Big day & massive congratulations to @OcanasSR from our group. She is an NIH Early Independence Awardee @NIH_CommonFund #NIHHighRisk. 1st award of this type in Oklahoma. We look forward to Sarah and her group being part of Genes & Human Disease Program at @OMRF.
Dr. Freeman has been received a Biomedical Laboratory Research and Development VA Research Career Scientist Award. @VAResearch is a critical funder of biomedical research to improve the lives of our nation's Veterans and all Americans.
In this #eNeuro study, @OcanasSR et al.@FreemanLabOMRF analyzed tissue dissociation & microglial sorting techniques in terms of yield, purity, & activational confounds to provide recommendations for optimal microglial isolation based on experimental needs. eneuro.org/lookup/DOI/10.…
Congratulations to PhD student Sarah Ocanas in the lab on her new publication - eneuro.org/content/early/…. A deep investigation of isolating microglia without causing artifacts.
Excited for support from #ImpetusGrants to push forward our understanding of epigenetic clocks
OMRF scientists Dr. Bill Freeman and Dr. Benjamin Miller recently received Impetus Grants to pursue bold ideas in #AgingBiology. omrf.org/2022/01/27/new…
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