Climate Change and Maternal Child Health Lab
@GayenLab_IISc
Srimonta Gayen's lab handle, Associate Professor, IISc Bangalore. Interests: DevBio | environment-epigenetics | X-chromosome inactiv-/upregul-ation | ageing
Interesting study identifying maternal lipidomic signatures where increased plasma triglycerides correlate with preterm birth risk. This analysis from cohorts in Bangladesh, Zimbabwe, and Kenya also showed decreased lipid levels preceding Small-for-Gestational-Age (SGA) births.
A new prospective @ScienceAdvances study involving more than 1000 pregnant women from three low- and middle-income countries suggests there is a relation between maternal lipid levels during pregnancy and preterm birth and gestational age. scim.ag/3KPyp54
Elated to share that @SharmistaSBio from our lab presented her work on #epigenetic regulation of neurodevelopmental disorders recently at the #BuildingBrains2025 workshop at @DBT_inStem. Acknowledge @iiscbangalore, @EMBO, @ANRFIndia, @DBTIndia for the support.
Dr Srimonta Gayen @iiscbangalore talked about maternal-child health in the face of climate change. He discussed how gestational heat-humidity affects epigenetics regulation & impairs morula to blastula transition resulting in implantation failure. #ReproNext #ReproductiveHealth
Excited to share our latest @PNASNews on cell-cycle stage-specific genome assembly of the meningitis-causing pathogen, brilliant work by @SatyaDev2064 in collab. w/ @ranjithpa and @DimpleNotani labs @jncasr @bose_institute @IndiaDST @ANRFIndia pnas.org/doi/10.1073/pn…
Many congratulations to all including Arnab, Soumyashree, Budhaditya, and Saravanan from India! Twelve scientists become EMBO Global Investigators. @EMBO_YIP @EMBO
Register Now — Limited Spots! atw2026.com Join ATW2026 (27–30 January 2026, Kolkata, India), the meeting on DNA damage & repair,chromatin organization, hosted by IACS and SINP. Meet global experts, share your work, and catch the latest in genome stability.
Li, J., Li, J., Cao, J. et al. Modelling late gastrulation in stem cell-derived monkey embryo models. Nature (2025). doi.org/10.1038/s41586…
The proliferation of clocks continues to reveal multiple proteomic organ aging clocks that provide a biologically interpretable framework for tracking #aging and disease risk across diverse populations. nature.com/articles/s4358…
New online! Heterochromatin boundaries maintain centromere position, size and number bit.ly/4ogJSbo
In this article (buff.ly/iWwXeLj) by Siddharth Singh, PhD student at @IITIOfficial, we learn how a mother’s gut microbes may influence fetal brain development.
Happy to share our paper on the reprogramming of H3K36me2 in early mouse embryos and its role in gene regulation! Heroic work and really huge efforts by Xukun Lu, Lijuan Wang and Yu Zhang. Many interesting findings for H3K36me2. Check it out! nature.com/articles/s4155…
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