manoliskellis's profile picture. Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstitute

Manolis Kellis

@manoliskellis

Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstitute

Przypięty

Kellis Lab is hiring! New grants in #Alzheimers #Schizophrenia #Cancer #EHR #SingleCell #Genome #Epigenome #Transcription #Disease integration. Computational & experimental positions, profiling and circuitry dissection. Join us! @MIT_CSAIL @BroadInstitute compbio.mit.edu/positions.html


So proud of #RileyMangan and #NikithaThoduguli presenting platform talks at #ASHG25 today on #SingleCell phenotypes for #Alzheimers, and #DeepLearning #Evolution of human cis-regulatory elements. Spread the word! @MIT @BroadInstitute @HarvardMed

manoliskellis's tweet image. So proud of #RileyMangan and #NikithaThoduguli presenting platform talks at #ASHG25 today on #SingleCell phenotypes for #Alzheimers, and #DeepLearning #Evolution of human cis-regulatory elements. Spread the word! @MIT @BroadInstitute @HarvardMed

MIT Course announcement: Machine Learning for Computational Biology #MLCB25 Fall'24 Lecture Videos: tinyurl.com/MLCBlectures Fall'24 Lecture Notes: tinyurl.com/MLCB24notes (a) Genomes: Statistical genomics, gene regulation, genome language models, chromatin structure, 3D genome…

manoliskellis's tweet image. MIT Course announcement: Machine Learning for Computational Biology #MLCB25
Fall'24 Lecture Videos: tinyurl.com/MLCBlectures
Fall'24 Lecture Notes: tinyurl.com/MLCB24notes
(a) Genomes: Statistical genomics, gene regulation, genome language models, chromatin structure, 3D genome…
manoliskellis's tweet image. MIT Course announcement: Machine Learning for Computational Biology #MLCB25
Fall'24 Lecture Videos: tinyurl.com/MLCBlectures
Fall'24 Lecture Notes: tinyurl.com/MLCB24notes
(a) Genomes: Statistical genomics, gene regulation, genome language models, chromatin structure, 3D genome…
manoliskellis's tweet image. MIT Course announcement: Machine Learning for Computational Biology #MLCB25
Fall'24 Lecture Videos: tinyurl.com/MLCBlectures
Fall'24 Lecture Notes: tinyurl.com/MLCB24notes
(a) Genomes: Statistical genomics, gene regulation, genome language models, chromatin structure, 3D genome…
manoliskellis's tweet image. MIT Course announcement: Machine Learning for Computational Biology #MLCB25
Fall'24 Lecture Videos: tinyurl.com/MLCBlectures
Fall'24 Lecture Notes: tinyurl.com/MLCB24notes
(a) Genomes: Statistical genomics, gene regulation, genome language models, chromatin structure, 3D genome…

Today was my last lecture for @MIT #ComputationalBiology: #Genomes, #Networks, #Evolution, #Health. I recorded each and immediately posted online here: youtube.com/playlist?list=… Please do share, and let me know which topics need more explanations, clarifications, and corrections!



Manolis Kellis podał dalej

Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma @NatureComms @gmboland @manoliskellis nature.com/articles/s4146…

LabWaggoner's tweet image. Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma @NatureComms @gmboland @manoliskellis
nature.com/articles/s4146…

Manolis Kellis podał dalej

I could never imagine combining deep conversations on #AI & #longevity with the beauty of my beloved Andros… until the AI Longevity Salon, hosted by @manoliskellis - where science met philosophy & ideas on longevity flowed. Thanks, Manolis, for the photos & the inspiring event.

skyriazakos's tweet image. I could never imagine combining deep conversations on #AI & #longevity with the beauty of my beloved Andros… until the AI Longevity Salon, hosted by @manoliskellis - where science met philosophy & ideas on longevity flowed.
Thanks, Manolis, for the photos & the inspiring event.
skyriazakos's tweet image. I could never imagine combining deep conversations on #AI & #longevity with the beauty of my beloved Andros… until the AI Longevity Salon, hosted by @manoliskellis - where science met philosophy & ideas on longevity flowed.
Thanks, Manolis, for the photos & the inspiring event.
skyriazakos's tweet image. I could never imagine combining deep conversations on #AI & #longevity with the beauty of my beloved Andros… until the AI Longevity Salon, hosted by @manoliskellis - where science met philosophy & ideas on longevity flowed.
Thanks, Manolis, for the photos & the inspiring event.
skyriazakos's tweet image. I could never imagine combining deep conversations on #AI & #longevity with the beauty of my beloved Andros… until the AI Longevity Salon, hosted by @manoliskellis - where science met philosophy & ideas on longevity flowed.
Thanks, Manolis, for the photos & the inspiring event.

Manolis Kellis podał dalej

Excellent talk by @manoliskellis at Athens College on AI and navigating complex data with Mantis. home.withmantis.com

apas's tweet image. Excellent talk by @manoliskellis at Athens College on AI and navigating complex data with Mantis. home.withmantis.com
apas's tweet image. Excellent talk by @manoliskellis at Athens College on AI and navigating complex data with Mantis. home.withmantis.com
apas's tweet image. Excellent talk by @manoliskellis at Athens College on AI and navigating complex data with Mantis. home.withmantis.com

Manolis Kellis podał dalej

If you are at ICML2025, welcome to attend our workshop "Multi-modal Foundation Models and Large Language Models for Life Sciences" tomorrow (Jul 19 Saturday). The workshop features a stellar lineup of invited speakers, including Valentina Boeva @val_boeva, Manolis Kellis…

cmuptx's tweet image. If you are at ICML2025, welcome to attend our workshop "Multi-modal Foundation Models and Large Language Models for Life Sciences" tomorrow (Jul 19 Saturday). 

The workshop features a stellar lineup of invited speakers, including Valentina Boeva @val_boeva, Manolis Kellis…
cmuptx's tweet image. If you are at ICML2025, welcome to attend our workshop "Multi-modal Foundation Models and Large Language Models for Life Sciences" tomorrow (Jul 19 Saturday). 

The workshop features a stellar lineup of invited speakers, including Valentina Boeva @val_boeva, Manolis Kellis…
cmuptx's tweet image. If you are at ICML2025, welcome to attend our workshop "Multi-modal Foundation Models and Large Language Models for Life Sciences" tomorrow (Jul 19 Saturday). 

The workshop features a stellar lineup of invited speakers, including Valentina Boeva @val_boeva, Manolis Kellis…

Greek friends, join us next Sunday July 6 in @Athens, as we hack the Future of #AI in the Cradle of Western Civilization, at the #EugenidesFoundation. After the success of our last hack at MIT, we're partnering with SundAI Club again to bring cutting-edge technologies to the…

manoliskellis's tweet image. Greek friends, join us next Sunday July 6 in @Athens, as we hack the Future of #AI in the Cradle of Western Civilization, at the #EugenidesFoundation. After the success of our last hack at MIT, we're partnering with SundAI Club again to bring cutting-edge technologies to the…
manoliskellis's tweet image. Greek friends, join us next Sunday July 6 in @Athens, as we hack the Future of #AI in the Cradle of Western Civilization, at the #EugenidesFoundation. After the success of our last hack at MIT, we're partnering with SundAI Club again to bring cutting-edge technologies to the…
manoliskellis's tweet image. Greek friends, join us next Sunday July 6 in @Athens, as we hack the Future of #AI in the Cradle of Western Civilization, at the #EugenidesFoundation. After the success of our last hack at MIT, we're partnering with SundAI Club again to bring cutting-edge technologies to the…
manoliskellis's tweet image. Greek friends, join us next Sunday July 6 in @Athens, as we hack the Future of #AI in the Cradle of Western Civilization, at the #EugenidesFoundation. After the success of our last hack at MIT, we're partnering with SundAI Club again to bring cutting-edge technologies to the…

If you love #Hacking and building the future of #AI, join us next Sunday May 18 for a joint #Hackathon with @Sundai_club (Boston), and Æthos (Berlin). You can be one of the first to build on our #Mantis Cognitive Cartography Platform for Human-driven AI-powered Visual Data…

manoliskellis's tweet image. If you love #Hacking and building the future of #AI, join us next Sunday May 18 for a joint #Hackathon with @Sundai_club (Boston), and Æthos (Berlin).

You can be one of the first to build on our #Mantis Cognitive Cartography Platform for Human-driven AI-powered Visual Data…


So excited to speak on #AI powered #DrugDiscovery at 10am this morning, at the @MIT Club of Boston @MITboston BioSummit on AI in HealthCare and Biotech. *Live now on Zoom*: lnkd.in/eqb88mbE Already 140 attendees and growing, please join us! @MIT_alumni @MITBiology @MITEECS

manoliskellis's tweet image. So excited to speak on #AI powered #DrugDiscovery at 10am this morning, at the @MIT Club of Boston @MITboston BioSummit on AI in HealthCare and Biotech.
*Live now on Zoom*: lnkd.in/eqb88mbE
Already 140 attendees and growing, please join us!
@MIT_alumni @MITBiology @MITEECS…

If you love #Hacking and building the future of #AI, join us next Sunday May 18 for a joint #Hackathon with @Sundai_club (Boston), and Æthos (Berlin). You can be one of the first to build on our #Mantis Cognitive Cartography Platform for Human-driven AI-powered Visual Data…

manoliskellis's tweet image. If you love #Hacking and building the future of #AI, join us next Sunday May 18 for a joint #Hackathon with @Sundai_club (Boston), and Æthos (Berlin).

You can be one of the first to build on our #Mantis Cognitive Cartography Platform for Human-driven AI-powered Visual Data…

Please join us for an @MITBiotechGroup and @MITEECS and @IEEEorg @TheACMG joint mixer tonight, at the interface of #ComputerScience and #Biology. Mixer from 6pm-7pm, and panel conversation from 7pm-8pm, in the @MIT #StataCenter student street, room 32-144. Excited to many of…

manoliskellis's tweet image. Please join us for an @MITBiotechGroup  and @MITEECS  and @IEEEorg @TheACMG  joint mixer tonight, at the interface of #ComputerScience and #Biology. Mixer from 6pm-7pm, and panel conversation from 7pm-8pm, in the @MIT #StataCenter student street, room 32-144. Excited to many of…

Join us to celebrate #Easter in the #Greek tradition at the heart of @MIT today. Roasting 5 whole lambs on a spit, grilling juicy pork souvlaki, Greek specialties including mousaka, pastitsio, tzatziki, horiatiki greek salad, galaktompoureko (google it!), baklava, and of course…

manoliskellis's tweet image. Join us to celebrate #Easter in the #Greek tradition at the heart of @MIT today. Roasting 5 whole lambs on a spit, grilling juicy pork souvlaki, Greek specialties including mousaka, pastitsio, tzatziki, horiatiki greek salad, galaktompoureko (google it!), baklava, and of course…
manoliskellis's tweet image. Join us to celebrate #Easter in the #Greek tradition at the heart of @MIT today. Roasting 5 whole lambs on a spit, grilling juicy pork souvlaki, Greek specialties including mousaka, pastitsio, tzatziki, horiatiki greek salad, galaktompoureko (google it!), baklava, and of course…
manoliskellis's tweet image. Join us to celebrate #Easter in the #Greek tradition at the heart of @MIT today. Roasting 5 whole lambs on a spit, grilling juicy pork souvlaki, Greek specialties including mousaka, pastitsio, tzatziki, horiatiki greek salad, galaktompoureko (google it!), baklava, and of course…
manoliskellis's tweet image. Join us to celebrate #Easter in the #Greek tradition at the heart of @MIT today. Roasting 5 whole lambs on a spit, grilling juicy pork souvlaki, Greek specialties including mousaka, pastitsio, tzatziki, horiatiki greek salad, galaktompoureko (google it!), baklava, and of course…

Manolis Kellis podał dalej

.@MIT_CSAIL Prof. @manoliskellis is reimagining healthcare with AI: from one-size-fits-all drugs to precision, modular treatments tailored to each patient’s biology. His lab is mapping disease at the molecular level to revolutionize drug discovery. More: bit.ly/43S6clm

csail_alliances's tweet image. .@MIT_CSAIL Prof. @manoliskellis is reimagining healthcare with AI: from one-size-fits-all drugs to precision, modular treatments tailored to each patient’s biology. His lab is mapping disease at the molecular level to revolutionize drug discovery.

More: bit.ly/43S6clm

Manolis Kellis podał dalej

Confirmed keynote speakers for the Greeks 🇬🇷 in #AI 2025 Symposium in Athens, Greece 🤗

CSProfKGD's tweet image. Confirmed keynote speakers for the Greeks 🇬🇷 in #AI 2025 Symposium in Athens, Greece 🤗

Coming this July, the Greeks 🇬🇷 in #AI 2025 Symposium in Athens, Greece.

CSProfKGD's tweet image. Coming this July, the Greeks 🇬🇷 in #AI 2025 Symposium in Athens, Greece.
CSProfKGD's tweet image. Coming this July, the Greeks 🇬🇷 in #AI 2025 Symposium in Athens, Greece.
CSProfKGD's tweet image. Coming this July, the Greeks 🇬🇷 in #AI 2025 Symposium in Athens, Greece.


Beautiful work by @KrithikTweets, @PardisSabeti, @Sameed, @_albertgu and team at @BroadInstitute @MIT @Harvard! Dramatic improvements in modeling and speed. AI for Biology and Medicine is continuing its amazing acceleration

🧬 Meet Lyra, a new paradigm for accessible, powerful modeling of biological sequences. Lyra is a lightweight SSM achieving SOTA performance across DNA, RNA, and protein tasks—yet up to 120,000x smaller than foundation models (ESM, Evo). Bonus: you can train it on your Mac. read…

KrithikTweets's tweet image. 🧬 Meet Lyra, a new paradigm for accessible, powerful modeling of biological sequences. Lyra is a lightweight SSM achieving SOTA performance across DNA, RNA, and protein tasks—yet up to 120,000x smaller than foundation models (ESM, Evo). Bonus: you can train it on your Mac.

read…


Excited to share our salon conversation on the Neuronal Basis of Consciousness with @KennethSKosik and #EmeryBrown. youtu.be/-4m0BTPPnoY Eager to hear your thoughts and comments, and also suggestions about future salon speakers, topics, and guests! @HarvardMed @BroadInstitute

manoliskellis's tweet card. Salon Neuronal Basis Of Consciousness Emery Brown Ken Kosik (Feb 25,...

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Salon Neuronal Basis Of Consciousness Emery Brown Ken Kosik (Feb 25,...


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