Jay Gertz
@GertzLab
Shameless promotion of our amazing gene regulation/cancer epigenetics work
You might like
Glad to share our latest work on The EstroGene2.0 database for endocrine therapy response and resistance in breast cancer models, now published in @Nature_NPJ #npjBCancer, shorturl.at/WPiJK, with the super-multifunctional browser estrogeneii.web.app
We thank NCI for supporting our work in 3D cancer genomics! This work was led by our grad student Katie Mortenson, co-supervised by K-T Varley, with close collaborations from Yang Liu, @GertzLab , and @Sven_Bailey.
Our latest Review is live! Thanks to @GertzLab and @RMJesel for your help and @EndoSocJournals for publishing! track.smtpsendmail.com/9032119/c?p=1c…
This excellent review on estrogen receptor alpha mutations, truncations, heterodimers, and therapies, goes into the history of ERα, current research unlocking unknown aspects of ERα signaling, and future directions of ESR1 investigation @RMJesel @GertzLab pubmed.ncbi.nlm.nih.gov/38643482/
Our work on how enhancers impact estrogen transcription timing and noise is now out in @CellGenomics! Thanks to everyone that helped out on this project! cell.com/cell-genomics/… @tweeterginley @xyzxiaoyang
The latest @GertzLab preprint was just posted. It was a great group effort led by @tweeterginley with help from @xyzxiaoyang lab and John Lis’ lab. In this study, we explored how regulatory elements influence gene expression timing and noise in response to estrogen 1/
Our latest review article on estrogen receptor targeted therapies in breast cancer has been published! academic.oup.com/endo/advance-a…
We are recruiting! Time to recirculate this work since there’s still so much to do. If you have expertise in DNA damage repair #DDR and are looking for a postdoctoral position where you can lead clinically-relevant discoveries, please don’t hesitate to reach out. @KUMedCenter
I am proud to share with you our recently published paper showing that obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2 science.org/doi/10.1126/sc…
This week is National #PostdocAppreciationWeek. Zannel Blanchard, PhD (@xedbee) is a postdoctoral fellow in the Welm lab. She explains the role of a postdoc, what inspired her to become a cancer researcher, and why she loves working here. #HCIproud
Want to work in the heart of Dublin where cutting-edge research meets a super friendly lab environment? 🍀 Dive into the world of breast cancer brain metastasis with us. Dublin’s warmth and our team’s camaraderie await you! Apply now: euraxess.ec.europa.eu/jobs/138568
Endometrial cancer is the most common gynecological cancer and high levels of estrogen promote its development. Researchers at HCI, led by @xedbee and @GertzLab, have identified potential new treatment options for people with endometrial cancer. bit.ly/47GqKwn
My pleasure to have officiated the Gordon Conference Hormone Dependent Cancers 2023 Breast Vs Prostate Football Match. The breast team emerged happy & victorious 4-2 🏆🍾 @MagnaniLab_ICR @oesterreichs @DanielFrigo @damirvareslija @dralexswarbrick @drmcrl @BevanLab @scottdehm
The second major publication from Zannel's PhD project in the @GertzLab is now published in Molecular Cancer Research. I'm thankful to have had the opportunity to help out on this work that further defines the effects of mutant Estrogen Receptor in #endometrialcancer
.@xedbee et al. show the ER-Y537S mutation mediates unique gene expression changes in #endometrialcancer, and identify CDK9 and NCOA3 as potential therapeutic targets. bit.ly/46MD65G @CraigRushPhD @SpencerArnesen @SigCris @Mattchles @hishammt @GertzLab
.@xedbee et al. show the ER-Y537S mutation mediates unique gene expression changes in #endometrialcancer, and identify CDK9 and NCOA3 as potential therapeutic targets. bit.ly/46MD65G @CraigRushPhD @SpencerArnesen @SigCris @Mattchles @hishammt @GertzLab
Congrats to @SpencerArnesen and the rest of the team!! Great to see this fun project out in @NAR_Cancer_EIC!
Excited to share that our recent work regarding the role of microRNAs in ER mutant breast cancer is now out in NAR Cancer! A big thanks to all involved! @GertzLab @xedbee @OConnellLab @AlanaWelm academic.oup.com/narcancer/arti…
academic.oup.com
Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through...
Abstract. Estrogen receptor α (ER) mutations occur in up to 30% of metastatic ER-positive breast cancers. Recent data has shown that ER mutations impact th
It was an honor to be included as one of the @huntsmancancer Breast and Gynecologic Cancer Rising Stars yesterday alongside @KLawsonMichod, Dr. Alessandra Riggio, and Dr. Christopher Weil. It's great to see the impactful work being done on women's cancers.
I'm hiring! I have a 2-year funded #endometrial #cancer project for a postdoc with #organoid culture experience. Based in Brisbane with views like this, how can you say no? HMU if you have Qs about the role. Applications close 6th June shorturl.at/abhlz
Congrats to Ozlen, Brooke and the rest of the gang for getting this preprint up and the formal manuscript under peer review. biorxiv.org/content/10.110…
Thanks to excellent collaborators on this review exploring AR functions across multiple cancer types! @jaleo_leo @NR_IMPACT @TheEndoSociety @mikeslivefdn @LWellberg @ED_PhD_ @Nate_WilsonMD @OAlhalabiMD @mcquadeMDLAc @ShannonWestin et al pubmed.ncbi.nlm.nih.gov/37154098/
Wu et al. show that ESR1 mutations promote FOXA1 localization to retinoid X receptor (RXR) motifs in ER+ #breastcancer, sensitizing breast cancer cells to RXR antagonists— bit.ly/3ADoN4N @ancasey8 @GertzLab @jennifermxavier @Adrianvlee @oesterreichs
Complementing the new postdoc position available in our lab imperial.ac.uk/jobs/descripti… is an opening for an experienced bioinformatics postdoc. imperial.ac.uk/jobs/descripti… DM or contact via the advertisement links.
United States Trends
- 1. Dame N/A
- 2. Valentine's Day N/A
- 3. Swayman N/A
- 4. Booker N/A
- 5. #NBAAllStar N/A
- 6. #NBAAllStar N/A
- 7. Denmark N/A
- 8. Jack Hughes N/A
- 9. Bobby Portis N/A
- 10. D Book N/A
- 11. #USAHockey N/A
- 12. Kentucky N/A
- 13. Rupp N/A
- 14. Austin Hill N/A
- 15. Rubio N/A
- 16. Brady Tkachuk N/A
- 17. Kon Knueppel N/A
- 18. Achilles N/A
- 19. Jamal Murray N/A
- 20. Providence N/A
Something went wrong.
Something went wrong.