The Guilak Lab
@Guilak_Lab
Official Twitter of @Farsh_G's research lab @ShrinersStLouis @WUSTL studying joint 💪 disease & regeneration #Arthritis #RegenerativeMedicine #Mechanobiology
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Just in case you thought he was done with just one national academy…today our fearless leader @Farsh_G got inducted into the @theNAMedicine!!! #NAE #NAM
⏰ Don’t forget! Nominations for the Farshid Guilak Outstanding Achievement in Mentoring Award are due September 26. Celebrate an exceptional mentor in the #ORScommunity who has guided and inspired your #orthopaedic research journey: ors.org/farshid-guilak…
🌟 Introducing the Farshid Guilak Outstanding Achievement in Mentoring Award. Honoring mentors who guide new investigators toward success in #orthopaedic research. Renamed to recognize Dr. Guilak’s remarkable impact on #musculoskeletal researchers. 🔗 bit.ly/45vqOPm
Congrats to Amanda Cimino and team on her latest paper in @JCRnEDITORS - she developed new synthetic chronogenetic gene circuits that allow controlled drug delivery at precise times day using various elements of the circadian clock! doi.org/10.1016/j.jcon…
Congrats to Amanda Cimino for her latest paper creating a chronogenetic gene circuit that automatically delivers anti-inflammatory biologic drugs in response to inflammation or circadian signal! jbioleng.biomedcentral.com/articles/10.11…
Join us today for our AOC Thought Leaders Webinar: Managing the Research Enterprise — for anyone navigating the evolving landscape of academic orthopaedics. April 24 | 4:00 PM ET Register Here: lnkd.in/eTrzEem6 Joint the AOC at myaocconnect.com!
Obesity has a distinct impact on the progression of OA. We showed significant loss of protective synovial lining macrophages in the synovium 3 days after joint injury, with a significant restoration in normal-weight but not in obese mice ard.eular.org/article/S0003-… @Farsh_G
A tip of the fez to the Edgar County Shrine Club for their incredible donation to the research department at @ShrinersStLouis. #Shriners #donation
Shameless plug: If you haven't tried it, I highly recommend this new party/meeting planning app, @partiful. It's the app of the day on the App Store - download for free! apps.apple.com/us/story/id177…
Proud and excited to be part of @shrinershosp @ShrinersStLouis!
Our new commercial is OUT NOW! 🎉 We are so proud to have many Shriners Children's St. Louis patients and medical staff featured front and center in this national campaign. ❤️ #pediatricorthopedics #TheMostAmazingCareAnywhere #ShrinersChildrens #OrthoTwitter
Congrats to Gabi Marushack and @AliSavadipour & team for our latest @Guilak_Lab paper showing that polyunsaturated fatty acids alter cell membrane properties & inhibit chondrocyte #mechanotransduction by #Piezo1 and #TRPV4. faseb.onlinelibrary.wiley.com/doi/10.1096/fj…
Huge congrats on an amazing dissertation and defense, Dr. Erica Ely @erica__ely! It's #Piezo month at @Guilak_Lab!
Members of the Guilak Lab have been hard at work this holiday season! 🎄 The team decorated gingerbread houses with their special signature - a mustache, in honor of their leader, Farshid Guilak, Ph.D. #ThankYouDonors #ShrinersChildrens @shrinershosp @Guilak_Lab @Farsh_G
Ph-done! Congrats Dr Daniel Palmer on an amazing PhD and defense!
I've been many things, but this is a first... 🥸
🎉New publication🎉 Ever wondered how cells transduce mechanical signals to the nucleus? Check out our latest publication from the @Guilak_Lab in collaboration with Dr. @MarinaDanalache lab: doi.org/10.1016/j.bbrc…
Yes, it's the time of year for Farshoween...
👏🏻👏🏻👏🏻 @Farsh_G @Guilak_Lab
Researchers at @ShrinersStLouis & @washu_ortho_res are pioneering gene therapy research to combat childhood obesity and arthritis risks. This new approach could be a game-changer for young patients' health. ow.ly/2uRN50TUBQV
Did you know that obesity causes cellular senescence in the joints? Check out our latest gene therapy - an enzyme called fat-1 that converts inflammatory fatty acids into anti-inflammatory ones - and reduces osteoarthritis and senescence! pnas.org/doi/10.1073/pn…
Congrats Ruhang Tang & @NHarasymowicz for our new @PNASNews paper on gene therapy for fat-1, an enzyme that converts 𝜔-6 fats (frying oil/meat) to 𝜔-3’s (fish/nuts). Increased 𝜔-3:𝜔-6 reduced inflammation, osteoarthritis, and markers of cell aging! pnas.org/doi/10.1073/pn…
Check out the latest from @Guilak_Lab on maternal health and reproduction in the MSK system - Exciting new findings on the effects of maternal and grandparent diet on skeletal health!
@NHarasymowicz and I are excited to share our latest manuscript showing maternal high-fat high-sugar diet impairs bone quality in two generations of mouse offspring in @JOrthopRes. @Farsh_G @khmoley onlinelibrary.wiley.com/doi/abs/10.100…
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