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Chimeric MHC class I and II-restricted non-self epitopes broaden anti-tumor T cell reactions. From Rongsheng Zhang, Tasuku Honjo, Kenji Chamoto and colleagues: hubs.la/Q03_6HQT0 📘 #Immunology Update Winter 2026 👉hubs.la/Q03_6Kh30
RNA anti-CRISPRs deplete Cas proteins to inhibit the CRISPR-Cas system dlvr.it/TQVhLR
Beige fat surrounding blood vessels actively works to keep high blood pressure in check, according to a new Science study in mice, promoting healthy vascular function even during obesity. The findings support the notion that therapeutic activation of thermogenic fat tissue…
In a new Science study, researchers report an unexpected role for sensory nerves in bone healing, providing insights into communication between the nervous system and the cells responsible for bone repair. Learn more in a new #SciencePerspective: scim.ag/3Nj6M5p
Monitoring markers of tau protein in the blood can predict functional outcomes in patients recovering from ischemic stroke better than MRI, according to a comprehensive study of more than 1200 patients in @ScienceTM. scim.ag/4sMNshe
From dysbiosis to longevity: a narrative review into the gut microbiome's impact on aging jbiomedsci.biomedcentral.com/articles/10.11…
Post-translational modification sites are present in hydrophilic cavities of alpha-synuclein, tau, FUS, and TDP-43 fibrils: A molecular dynamics study: onlinelibrary.wiley.com/doi/10.1002/pr…
Exploiting the polypharmacology of alectinib for synergistic RNA splicing disruption with RBM39 degraders dlvr.it/TQP2BN
NEW content online! Heterocellular crosstalk and architecture of the pancreatic tumour microenvironment dlvr.it/TQNl6c
Heterochronic parabiosis alters the transcriptomic landscape to combat aging and aging-related diseases in aging-accelerated mice pmc.ncbi.nlm.nih.gov/articles/PMC12…
In a new Science study, researchers introduce DrugCLIP, a contrastive learning framework that virtually screens small molecules and protein pockets, analyzing protein-ligand interactions 10 million times faster than most standard molecular docking approaches.…
New preclinical work in @SciSignal reveals how #Tcells respond in real time to signaling inputs of varying intensities and could shed further light on how these cells become activated in the context of immunity and inflammation. scim.ag/3Zb5Q5D
Epitranscriptomic control of cancer hallmarks: Functions, mechanisms, and therapeutics of RNA modifications dlvr.it/TQMtR3
How does obesity lead to immune system dysregulation and chronic inflammation? Macrophage metabolism is rewired, with activation of the NLRP3 inflammasome @ScienceMagazine science.org/doi/10.1126/sc…
Monitoring markers of tau protein in the blood can predict functional outcomes in patients recovering from ischemic stroke better than MRI, according to a comprehensive study of more than 1200 patients in @ScienceTM. scim.ag/4sMNshe
RNA-binding proteins and ribonucleoproteins as determinants of immunity dlvr.it/TQMKKq
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