HirschiLab's profile picture. Vascular Development Research || University of Virginia
Tweets by lab members

Hirschi Lab

@HirschiLab

Vascular Development Research || University of Virginia Tweets by lab members

Congratulations and best of luck @nickchavkin! We're excited to see what you find. We'll miss you at UVA!

Exciting news to share - I accepted an Assistant Professor position to start my lab at Seattle Children's Research Institute and @uwpediatrics! I start on July 1st in the Center for Developmental Biology and Regenerative Medicine. chavkinlab.com



Hirschi Lab hat repostet

I can’t wait to see @MTorrescnic, @makinenlab, @MarionaGraupera and @HirschiLab at this year’s Seeon meeting, where they will discuss concepts of cellular fitness, competition, and clonality in the cardiovascular system. For applications, visit: vwfb.de.

PotenteLab's tweet image. I can’t wait to see @MTorrescnic, @makinenlab, @MarionaGraupera and @HirschiLab at this year’s Seeon meeting, where they will discuss concepts of cellular fitness, competition, and clonality in the cardiovascular system. For applications, visit: vwfb.de.

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Congratulations to Dr. Yen-Lin Chen from @sonkusarelab on his K99/R00 award for studying lymphatic endothelial Piezo1 and TRP channels in obesity! Many thanks to co-mentors and collaborators @ScallanLab, @HirschiLab, @conn_pann_fun @NIDDK @UVACVRC

sonkusarelab's tweet image. Congratulations to Dr. Yen-Lin Chen from @sonkusarelab on his K99/R00 award for studying lymphatic endothelial Piezo1 and TRP channels in obesity! Many thanks to co-mentors and collaborators @ScallanLab, @HirschiLab, @conn_pann_fun @NIDDK @UVACVRC

Hirschi Lab hat repostet

Excited to share our now-published work showing that obesity accelerates EndoMT in adipose tissue! @FrontCVMedicine. Using lineage-tracing mouse models, human cell culture assays, and human scRNAseq datasets, we show that obesogenic diet promote EndoMT. tinyurl.com/3bkffkdj


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Really amazing study here - outstanding work from @WesleyAbplanalp @StefanieDimmel1. I was able to help write a News & Views on this article as well: nature.com/articles/s4416… New technique that helped identify how small clone sizes in CHIP have large effects.

Clonal hematopoiesis affects only a small number of cells in the blood. @WesleyAbplanalp now developed a method that demonstrates the specific effect in the mutated cells. Not only monocytes but also T-cells are affected! Learn more here: nature.com/articles/s4416… @NatureCVR

StefanieDimmel1's tweet image. Clonal hematopoiesis affects only a small number of cells in the blood. @WesleyAbplanalp now developed a method that demonstrates the specific effect in the mutated cells. Not only monocytes but also T-cells are affected! Learn more here: nature.com/articles/s4416… @NatureCVR


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Cool comparisons between different vascular beds and the endothelium within them. Thanks to @Luke_Dunaway and @melissa_luse for co-leading the way on this.

Our latest preprint is up! Check out mine and @melissa_luse work investigating endothelial heterogeneity in obesity using bulk seq, scRNA seq, and some beautiful en face imaging of arterial endothelial mitochondria! @conn_pann_fun biorxiv.org/content/10.110…



Congrats to postdoc Yinyu Wu on her recent @Dev_Cell paper titled "MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis". Great work! 👏🎉@UVACVRC @YaleCVRC @MedicineUVA @YaleGenetics


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In our latest episode, we discuss a study from the lab of Dr. Karen Hirschi (@HirschiLab) at @Yale. Her lab identified miR-223 as a negative regulator of murine hemogenic endothelial cell specification and #myelopoiesis. 📒: bit.ly/3Jb450Q 🎧: bit.ly/3J6pckY

stemcellpodcast's tweet image. In our latest episode, we discuss a study from the lab of Dr. Karen Hirschi (@HirschiLab) at @Yale. 

Her lab identified miR-223 as a negative regulator of murine hemogenic endothelial cell specification and #myelopoiesis.

📒: bit.ly/3Jb450Q
🎧: bit.ly/3J6pckY

Hirschi Lab hat repostet

A recent study by @HirschiLab identified microRNA-223 as a negative regulator of murine hemogenic #endothelial cell specification and endothelial-to-#hematopoietic transition. @UVACVRC @YaleGenetics 🖨️ Published in @Dev_Cell! bit.ly/3Jb450Q

endothelialnews's tweet image. A recent study by @HirschiLab identified microRNA-223 as a negative regulator of murine hemogenic #endothelial cell specification and endothelial-to-#hematopoietic transition. @UVACVRC @YaleGenetics

🖨️ Published in @Dev_Cell! 
bit.ly/3Jb450Q

Hirschi Lab hat repostet

I was honored to chair the #regenerative_medicine session at @CURAMdevices summit 2023 with prof. Murphy. Including outstanding talks from prof. Hirschi @HirschiLab, prof. @johnglaffey, Dr. @MeadhbhBrennan, and Dr. @JohnJMulvihill 🍀

mohammad7moosav's tweet image. I was honored to chair the #regenerative_medicine session at @CURAMdevices summit 2023 with prof. Murphy. 
Including outstanding talks from prof. Hirschi @HirschiLab, prof. @johnglaffey, Dr. @MeadhbhBrennan, and Dr. @JohnJMulvihill 🍀
mohammad7moosav's tweet image. I was honored to chair the #regenerative_medicine session at @CURAMdevices summit 2023 with prof. Murphy. 
Including outstanding talks from prof. Hirschi @HirschiLab, prof. @johnglaffey, Dr. @MeadhbhBrennan, and Dr. @JohnJMulvihill 🍀

Congratulations to grad student Ola Cwiek for winning the Hiroko Nishimura Award for best trainee presentation at the CHRC's Pediatrics Annual Research Symposium! Fantastic work! 👏

I was awarded the Hiroko Nishimura award for the best trainee presentation during the 35th Pediatrics Annual Research Symposium at @UVA_CHRC, and I learned a lot about prematurity from @MugliaLouis! 🎉 @HirschiLab @uva_bims @UVa_CellBio

CwiekAleksandra's tweet image. I was awarded the Hiroko Nishimura award for the best trainee presentation during the 35th Pediatrics Annual Research Symposium at @UVA_CHRC, and I learned a lot about prematurity from @MugliaLouis! 🎉 @HirschiLab @uva_bims @UVa_CellBio


Hirschi Lab hat repostet

Dr. karen Hirschi on “role of endothelial cell hyperproliferation and AVMs” 📌 Data showing control of endothelial cell proliferation prevents AVM formation. ⁉️ Can endothelial cell cycle inhibitors be used to treat AVMs? #VascularDiscovery23 @AHA_Research @CouncilPvd

AHAScience's tweet image. Dr. karen Hirschi on “role of endothelial cell hyperproliferation and AVMs” 
📌 Data showing control of endothelial cell proliferation prevents AVM formation.
⁉️ Can endothelial cell cycle inhibitors be used to treat AVMs?

#VascularDiscovery23 @AHA_Research @CouncilPvd
AHAScience's tweet image. Dr. karen Hirschi on “role of endothelial cell hyperproliferation and AVMs” 
📌 Data showing control of endothelial cell proliferation prevents AVM formation.
⁉️ Can endothelial cell cycle inhibitors be used to treat AVMs?

#VascularDiscovery23 @AHA_Research @CouncilPvd
AHAScience's tweet image. Dr. karen Hirschi on “role of endothelial cell hyperproliferation and AVMs” 
📌 Data showing control of endothelial cell proliferation prevents AVM formation.
⁉️ Can endothelial cell cycle inhibitors be used to treat AVMs?

#VascularDiscovery23 @AHA_Research @CouncilPvd
AHAScience's tweet image. Dr. karen Hirschi on “role of endothelial cell hyperproliferation and AVMs” 
📌 Data showing control of endothelial cell proliferation prevents AVM formation.
⁉️ Can endothelial cell cycle inhibitors be used to treat AVMs?

#VascularDiscovery23 @AHA_Research @CouncilPvd

Hirschi Lab hat repostet

So incredibly proud of @CwiekAleksandra and her work. Presented today at #pas2023 Congratulations!!!

JenniferCharlt7's tweet image. So incredibly proud of @CwiekAleksandra and her work. Presented today at #pas2023 Congratulations!!!
JenniferCharlt7's tweet image. So incredibly proud of @CwiekAleksandra and her work. Presented today at #pas2023 Congratulations!!!

Welcome Josh and the @wythelab! We are thrilled to have you join @UVa_CellBio @MedicineUVA and are excited to start working together!

I was awarded the Hiroko Nishimura award for the best trainee presentation during the 35th Pediatrics Annual Research Symposium at @UVA_CHRC, and I learned a lot about prematurity from @MugliaLouis! 🎉 @HirschiLab @uva_bims @UVa_CellBio

CwiekAleksandra's tweet image. I was awarded the Hiroko Nishimura award for the best trainee presentation during the 35th Pediatrics Annual Research Symposium at @UVA_CHRC, and I learned a lot about prematurity from @MugliaLouis! 🎉 @HirschiLab @uva_bims @UVa_CellBio


Hirschi Lab hat repostet

A recent study by the @HirschiLab at @MedicineUVA shows that vascular #endothelial cell-expressed Cx43 regulates adult #NSC proliferation and differentiation. #neurogenesis More in @CellReports. 📚 bit.ly/41pby31

NeuralCell's tweet image. A recent study by the @HirschiLab at @MedicineUVA shows that vascular #endothelial cell-expressed Cx43 regulates adult #NSC proliferation and differentiation. #neurogenesis 

More in @CellReports.
📚  bit.ly/41pby31

Congrats to @nafiishaGenet on her great work just published in @CellReports!

I'm excited to announce the publication of my latest article from @HirschiLab , titled "Connexin-43 mediated Neurovascular Interactions regulate Neurogenesis in the Adult brain subventricular zone," in Cell Reports. @uva_ec @UVa_CellBio @UVACVRC



Congrats to Hirschi Lab postdocs @nafiishaGenet and @nickchavkin on each receiving their own @AHAScience Career Development Award! We are so excited to see where their research leads! 🧬❤️ @UVa_CellBio @UVACVRC

HirschiLab's tweet image. Congrats to Hirschi Lab postdocs @nafiishaGenet and @nickchavkin on each receiving their own @AHAScience Career Development Award!  We are so excited to see where their research leads! 🧬❤️ @UVa_CellBio @UVACVRC
HirschiLab's tweet image. Congrats to Hirschi Lab postdocs @nafiishaGenet and @nickchavkin on each receiving their own @AHAScience Career Development Award!  We are so excited to see where their research leads! 🧬❤️ @UVa_CellBio @UVACVRC

Wonderful time at the Vascular Cell Biology @GordonConf in Ventura last week! Really inspiring work presented by everyone involved, thanks to @AranyLab for organizing a great meeting. Excited for the next one in January 2025!

HirschiLab's tweet image. Wonderful time at the Vascular Cell Biology @GordonConf in Ventura last week! Really inspiring work presented by everyone involved, thanks to @AranyLab for organizing a great meeting. Excited for the next one in January 2025!

Congratulations to our grad student @CwiekAleksandra for receiving an @AHAScience Predoctoral Fellowship studying retinoic acid regulation of placental vascularization! So well deserved! 👏👏👏 @UVa_CellBio

HirschiLab's tweet image. Congratulations to our grad student @CwiekAleksandra for receiving an @AHAScience Predoctoral Fellowship studying retinoic acid regulation of placental vascularization! So well deserved! 👏👏👏 @UVa_CellBio

Hirschi Lab hat repostet

Congratulations to the members of the BIMS 2020 cohort who have completed their quals/proposal defense and have advanced to CANDIDACY! 💙🧡 We were honored to have @DeanMKibbe join us and share her experiences at the bench and encouraging words for the time ahead. @MedicineUVA

uva_bims's tweet image. Congratulations to the members of the BIMS 2020 cohort who have completed their quals/proposal defense and have advanced to CANDIDACY! 💙🧡
We were honored to have @DeanMKibbe join us and share her experiences at the bench and encouraging words for the time ahead. @MedicineUVA

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