Michael Koldobskiy MD PhD / Koldobskiy Lab
@KoldLab
Pediatric oncology, Neuro-oncology, Epigenetics. Research Lab @JohnsHopkins @hopkinskimmel
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Announcing the release of the Roadmap for the Treatment of Pediatric DMG today in @Cancer_Cell which was led by @vennetilab and @KoschmannLab and put together by the brilliant team of researchers who came together for the @chadtough Defeat DIPG Workshop: sciencedirect.com/science/articl…
So happy to share our consensus paper on understanding and treating #DIPG from the @chadtough foundation workshop held this year in #AnnArbor. Thank you to our amazing scientists, collaborators, and families who made this possible!!! cell.com/cancer-cell/fu…
Looking to hire a research tech and a post-doc for the Ding Lab at @HopkinsMedicine, which focuses on using new sequencing technologies to discover new therapeutic targets and overcome resistance in pediatric leukemias. Info here: dinglaboratory.wixsite.com/home
Hyundai Hope On Wheels Children’s Hospital Johns Hopkins Helping Kids Fight Cancer @WMAR2News has the story
Really happy to see the wonderful work from colleagues in Rome using 3rd gen GD2 CARs for neuroblastoma. This is the largest series of CAR T responses in a solid tumor to date & the fact that it’s in a pediatric cancer is awesome! Bravo! nejm.org/doi/full/10.10…
It was wonderful to present our work with @BonifantLab on CAR-NK cell targeting of Acute Myeloid Leukemia and Lectin-CAR engineered NK cells for SARS-CoV-2 clearance at #ASH2021. Honored to be among the Abstract Achievement Award Recipients! #Immunotherapy #CAR_NK #AML #SARSCoV2
Just in! New medicine laureate Ardem Patapoutian and his son Luca, watching the #NobelPrize press conference shortly after finding out the happy news. Stay tuned for our interview with Patapoutian coming up soon! Photographer: Nancy Hong
We are ecstatic to announce that the ChadTough Defeat DIPG Foundation has granted an additional $3.5 million toward pediatric brain cancer research. #ChadToughDefeatDIPG #ChadTough #DefeatDIPG #DIPG #TougherTogether chadtough.org/largest-fundin…
Damon Runyon Alumnus @KoldLab & colleagues at @HopkinsMedicine introduced a new method to analyze methylation patterns across the entire genome of #acutelymphoblasticleukemia (ALL) patients—providing remarkable insight into the #epigenetic drivers of ALL: bit.ly/3fOuBxx
“brain cancer is the deadliest form of pediatric cancer. Nearly 5,000 children in the US are diagnosed with brain tumors each year. Despite that fact, no drug has ever been developed and approved specifically for children with brain tumors.” cnn.com/2021/05/09/opi…
Illustration: DNA methylation can be analyzed using information theory (represented by strings of 0s and 1s) to understand the epigenetic landscape of cancer and identify genes that regulate this landscape. Credit: Kate Zvorykina (Ella Maru Studio) bit.ly/3sz62sN
'Information theory' recruited to help scientists find cancer genes bit.ly/3sz62sN via @HopkinsMedicine @EurekAlert
The availability of higher-quality biomedical and clinical data is widening the reach and usefulness of data-fitted biophysical models and of data-driven mathematical and statistical modelling. nature.com/articles/s4155…
Excited to share our new paper with Andy Feinberg @TheFeinbergLab and John Goutsias on epigenetic drivers of childhood ALL (most common #cancer in children), supported by @DamonRunyon and @StBaldricks
Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis rdcu.be/ciK9y
(Pre-COVID-19 photos) @Hyundai @hopeonwheels supports our research on the deadliest pediatric cancer, diffuse intrinsic pontine glioma #dipg. Photo: Hand-print ceremony at @hopkinskimmel 2019
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