
Jacks Lab
@LabJacks
The Jacks Lab, established in 1992. Koch Institute for Integrative Cancer Research at MIT. Cancer genetics. GEMMs. Tumor immunology. Run by lab members.
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The Lab Christmas tree is officially lit! Happy holidays to all :)

Excited to announce the Yang lab officially opens at @Columbia University. We are interested in developing innovative single cell recording technologies to study tumor evolution and cancer plasticity. We are hiring motivated postdocs & students, please RT dianyanglab.com
Out today, with @LabJacks, @isidrolauscher, @fran_muyas, we used new mouse models of spontaneous lung and colon cancer to delineate a mechanism for why many patients with DNA mismatch repair deficient (MMRd) tumors may not respond to immunotherapy 🧵1/11 nature.com/articles/s4158…
A heartfelt farewell to our amazing summer students Safya and Michelle! Congratulations on the amazing work and posters!



Our prime editor mouse is now available to request from The Jackson Laboratory: jax.org/strain/037953 jax.org/strain/037954
A prime editor mouse to model a broad spectrum of somatic mutations in vivo go.nature.com/3Bk8fz4

Tyler Jacks’ Keynote Lecture: “Genetic engineering meets tumor immunology: Lessons from mouse models of cancer” @LabJacks #eacrImmunoOncology


Tyler Jacks from @kochinstitute @MIT presenting eloquent vignettes (called tapas while @EACRnews #eacrImmunoOncology in Spain) on genetic engineering approaches in mice that have revealed profound insights into immuno-oncology and novel targets.

Ludwig @MIT Co-director Tyler Jacks spoke at #AACR2023 about the use of mouse models of cancer—further engineered to express cancer antigens or accumulate mutations in cancer cells—as a tool for nuanced and comprehensive study of anti-tumor immune responses.

Great to see our very own @KarenKarenoyee featured in @kochinstitute my voices! Thank you Karen for all you do!

We are currently hiring technicians! Apply if you're interested in 🐭 models of cancer, there are opportunities across cancer types and all of our research areas: careers.peopleclick.com/careerscp/clie…
Tried and failed to go the the @muddycharlespub and revive lab Muddy Wednesdays (they were closed) 😭, but succeeded at having a great time!

Congratulations to Tyler Jacks, recipient of the Ernst W. Bertner Memorial Award! Professor Jacks will be giving his award lecture and presentation at 2022 Leading Edge Symposium at MD Anderson on Thurs. November 17. mdanderson.org/research/resea…

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