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Excited to share a recent preprint from us: chemrxiv.org/engage/chemrxi… Herein, we outline a highly promising electrocatalytic cascade that enables access to various halogenated amides, carbamates and ureas at room temperature without added catalysts, additives or electrolytes.
From now on news and updates about the Verho group will be posted on our Bluesky account: bsky.app/profile/verhog…. As a result, updates here will be discontinued
Preprint #2 announcement. chemrxiv.org/engage/chemrxi… Herein, we present a cobaltaelectro-catalyzed protocol for room temperature C-H acyloxylation of a variety of aromatic and vinylic amide scaffolds, with possible applications relating to the late-stage functionalization of drugs.
New paper fresh out of the press onlinelibrary.wiley.com/doi/10.1002/ad…. In this paper, we present a highly general and practical method for chlorinating heterocyclic compounds through the use of Pd catalysis and electrochemistry. Kudos to the team involved! @FFakulteten @UU_University
Interesting Half-term Seminar coming up with Chris Mitrogiannis, PhD Student at @LabVerho, presenting his ongoing research to develop a novel DNA-encoded peptide library and a DNA-compatible phthalimide deprotection strategy ✅ Join Tuesday 15 October, 14:00 at BMC, room A5:208b
Congratulations to graduate student Ottilia Andersson in our lab completing her PhD half-time seminar excellently. Exciting work related to DNA-encoded libraries and antibiotic drug discovery to come soon from her PhD research.
We also celebrate today the half-way mark of @OttiliAndersson to her PhD on #MedicinalChemistry - optimizing a very cool way to make chemical libraries to find new #antibiotics - DNA-encodes libraries. This way one can make a very large library in a short amount of time!
Happy to share another preprint freshly out of our own lab. This time, we present a highly general and operationally-simple method for the chlorination of various heteroarene frameworks by combining Pd catalysis and electrochemical oxidation: @ChemRxiv - go.shr.lc/3VUNlBH
Midsummer salutations from the Verho lab! Happy to share a recent preprint from a multicentered collaboration we participated in, which shows the power of the DNA-encoded library technology in furnishing nM starting points for an important disease target! biorxiv.org/content/10.110…
Very excited to see the new homepage for our Drug Design and Discovery supergroup finally online: uu.se/en/department/…. Here, our group will contribute to the further development of this page by providing highlights and news from our research. Don't miss out! @uppsalauni
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