Woolner Lab
@LabWoolner
Sarah Woolner's lab at the University of Manchester, UK. We investigate mechanical regulation of cell division in developing tissues.
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The localisation of the mitotic spindle orientation protein, NuMA, is highly dynamic and sensitive to tissue stretch. Frogs are also great for live imaging 🐸 Check out our preprint: biorxiv.org/content/10.110…
Check out our new preprint on bioRxiv. We show that NuMA localisation is sensitive to tissue stretch and acts to fine-tune division orientation. Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tissue stretch via NuMA localisation biorxiv.org/content/10.110…
Baby you’re a fiiiiirework!!! Explanted Xenopus neural crest cell, microtubules (green) and actin (magenta). Imaging in frogs rocks- this is done room temp, no incubation, no problem. 🐸🔬✨ By Micaela Lasser, Helen Willsey @goodfrognosis Lab @zeiss_micro LSM980 fast airyscan
Now online at Bull. Math. Bio. doi.org/10.1007/s11538…
Relaxation and noise-driven oscillations in a model of mitotic spindle dynamics, with Dionn Hargreaves and @LabWoolner arxiv.org/abs/2402.10638
Come join the Manchester Xenopus community: the Dorey lab are recruiting a Research Associate to study the response of neural progenitor cells to spinal cord injury. jobs.manchester.ac.uk/Job/JobDetail?…
We are thrilled to announce that our @wellcometrust application to establish a Discovery Research Platform for Cell-Matrix Biology @OfficialUoM was successful! 🎉 Here’s what to expect #cellmatrixbiology 👇 (thread)
Discovery research has near limitless potential, but researchers can be faced with barriers too substantial to overcome alone. To address this, we are directing £73 million into eight new Discovery Research Platforms. Learn more ⤵️ wellc.me/416bBjJ
Interested in how mechanical forces regulate cells and tissues? We're looking for a postdoc, ideally with experience in proteomics, to join us in the Woolner lab. jobs.manchester.ac.uk/displayjob.asp…
Thanks @YanlanMao for setting up this petition. Age limits on fellowships/grants are stifling and can prevent the best research being funded. Remove academic age limits on ERC grants - Sign the Petition! chng.it/9SLy7pNf via @UKChange
Post-doc position available modelling epithelial mechanics, closing date 19 Sept 2022 jobs.ac.uk/job/CSR834/res… @LabWoolner @ManUniMaths
🚨 Application deadline *tomorrow* for a postdoc with me @mathsatshefuni @shefmathbio on modelling tissue patterning - please consider applying, or forwarding on to anyone who might be interested! jobs.ac.uk/job/CQL924/res…
Biggest story on the front page of the Financial Times. Rightly. UK commits scientific, business and cultural suicide.
My latest for @ftopinion on the insanity of leaving HorizonEurope, how 🇬🇧 gov policy is slowly destroying British science & why academics are leaving. #Science ft.com/content/a66e17… via @financialtimes
New pre-print alert from the Miller lab @UMich_MCDB 🎉 Grad student @ShahanaChumki1 shows how Rho-mediated junction remodeling is regulated in developing epithelia. Check it out! 🐸👀🔥
p115RhoGEF activates RhoA to support tight junction maintenance and remodeling biorxiv.org/cgi/content/sh… #biorxiv_cellbio
Roberto @mayor_lab zooms in after his talk this morning to help out with some neural crest explants!
Started the day off with a fantastic lecture by Sarah Woolner @LabWoolner Stoked to check out some animal caps later today!
We are so looking forward to the BSDB Spring Meeting this year. We once again join forces with our friends at @Official_BSCB. Check out the programme, submit your abstract, and register here: registrations.hg3conferences.co.uk/hg3/frontend/r…
Congratulations @emmaljohns on passing your viva yesterday! Thanks to @integrintraffic and @AlexGFletcher for acting as examiners. In addition to being an amazing interdisciplinary scientist, Dr Johns is also a fabulous potter, check out the family of frogs she made for us 🐸🐸🐸
New on the Node: BSDB Gurdon Summer Studentship Report – Stephanie Leadbitter Read about Stephanie's research on mechanical regulation of cell division in developing tissues in the @LabWoolner @OfficialUoM , funded by a Gurdon/@_BSDB_ summer studentship
The amazing Andrea Wills @WillsLabFroggos gives the Inaugural IXB Young Investigator Award Lecture at #frogfest21 #womeninstem
Kick ass talk from @RobertJHuebner1 at #frogfest2021! If you wanna read more about it, check out his paper in @biorxivpreprint: biorxiv.org/content/10.110…
Great to see a dispatch about our new paper in Current Biology. Thanks @helenkmatthews! Cell biology: How cancer cells coerce normal cells into tumorigenesis sciencedirect.com/science/articl…
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