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Excited to share our first cryo-EM paper, which was just published in Nucleic Acids Research: academic.oup.com/nar/advance-ar… We investigate a new family of RNases with crystal and cryo-EM structures. Congrats Ruoxi!
Our new paper on SUGCT is out, in collaboration with the Houten Lab. Congrats Ruoxi and Susmita! pubs.acs.org/doi/10.1021/ac…
pubs.acs.org
Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a...
Glutaric Aciduria Type 1 (GA1) is a serious inborn error of metabolism with no pharmacological treatments. A novel strategy to treat this disease is to divert the toxic biochemical intermediates to...
Excited to share our new paper on autophagy and cancer: pubs.acs.org/doi/10.1021/ac… Congrats Kisa, Agata, and Carisse! We found a new link between autophagy inhibition and the cell cycle. Also we show that many autophagy inhibitors are dirty. Be careful!
Excited for our latest paper: royalsocietypublishing.org/doi/10.1098/rs… A collaboration with @SanderHouten and DeVita Labs at Mount Sinai. The first structure of an interesting metabolic enzyme and a curious case of allostery. Stay tuned for more on this project! Congrats to everyone involved!
Congrats @KupfermanTania and the NYU team on the convalescent plasma study for COVID-19
Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients ja.ma/3pMSPx4 via @JAMAInternalMed part of @JAMANetwork
Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients ja.ma/3pMSPx4 via @JAMAInternalMed part of @JAMANetwork
Excited to be part of #Target2035 today!
Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients ja.ma/3pMSPx4 via @JAMAInternalMed part of @JAMANetwork
The Lazarus Lab is hiring! We're looking for a postdoc to work on our NIH-funded Alzheimer's project. Neuronal cell culture and autophagy experience are a plus! #drugdesign For more info and to apply, go here: careers.mountsinai.org/jobs/2702054?l… @IcahnMountSinai @SfNtweets
I have a protein crystallography joke for you, but I think it may be salty.
Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients ja.ma/3pMSPx4 via @JAMAInternalMed part of @JAMANetwork
Our team's new paper and new structure of DHTKD1 is out in ACS Chem Bio, led by the lab of @SanderHouten and our collaborators at Mount Sinai, UCSF, and Rutgers. pubs.acs.org/doi/10.1021/ac…
pubs.acs.org
Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex
DHTKD1 is the E1 component of the 2-oxoadipate dehydrogenase complex, which is an enzyme involved in the catabolism of (hydroxy-)lysine and tryptophan. Mutations in DHTKD1 have been associated with...
Proud of this new paper led by Michael Lazarus @LazarusLab on the structural characterization of the schizophrenia-linked pseudokinase ULK4. A really intriguing protein. pubs.acs.org/doi/full/10.10…
The first paper of the Lazarus Lab is out! pubs.acs.org/doi/abs/10.102… We solved the first structure of a cool pseudokinase that is implicated in schizophrenia
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