Dr. Noel Carrascal
@LowKeyBiohacker
Computational Protein Designer, Chemist and Programmer. Founder of Entropy Maxima, LLC.
قد يعجبك
Well, Bohr's model of the Atom has not held up; and Einstein's "Space-Time" gravity view is still Sci-Fi. And neither could explain how an Atom creates Gravity. All that is known about Gravity today is, Gravity gets stronger with increasing density of Atoms in a volume.
why do this headlines grab us? this is fantastical in a bad way. the math is not like a blue print to build a time machine.. the proof is then something else,
"In a peer-reviewed paper, a scientist says he has mathematically proven the physical feasibility of a specific kind of time travel. The paper appears in Classical and Quantum Gravity." via @PopMech realclearscience.com/2024/12/27/par…
Did you ever hear about the babysecond before? Visualizing the Nucleus youtu.be/ach9JLGs2Yc?si… via @YouTube
youtube.com
YouTube
Visualizing the Nucleus
There are groups that approach protein folding/design from a more rational perspective than alpha fold/Bakers-lab reapectively.That the price was given more for folds and designs obtained not always from a purely physical model speaks volumes of the knowledge gap in those fields
Baker deserves the Nobel; Alpha Fold, I do not know. The irony is that alpha fold outperformed Baker's software, but 1/2 the Nobel was given to Baker. Some say Hassibis, winner of 1/4 Nobel doesn't deserve it. Baker work contributed to Randy Schekman's medicine Nobel prize, hmm
Baker is the most prominent figure in the field. IMO, he is only the second and purely computational chem/bio scientist to win the Nobel Prize after Martin Karplus. A great field with a lot of potential for positively impacting humanity. Who will the 3rd one be? Any suggestions?
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
NASA Discovers Third Global Energy Field – As Fundamental as Earth’s Gravity and Magnetic Fields scitechdaily.com/nasa-discovers…
It’s absolutely misguided to think that scientists using bloated, overly complicated language in their papers are somehow impressive to other scientists In reality the opposite is the case. It’s impressive if you can communicate complicated ideas in simple terms.
De Broglie wavelength for an electron, λ = ʰ⁄ₚ where, λ = wavelength h = Planck's constant (6.62607015×10⁻³⁴ J.s) p = momentum
One of the strangest coincidences in physics is the fact that Newtonian fluid dynamics in three dimensions is exactly equivalent to a scalar field theory in FOUR dimensions, with a Lorentzian signature metric. I know of no intuitive reason for this to be true, but it is.
I'm looking for recent (<10y) #compchem papers that predicted phenomena before any experiments. It's for a talk on this topic. Do you know any? Please send me the DOI.
This "frugal CRISPR kit" costs about $2. It includes a cell-free extract (no living cells), plasmids encoding colorful proteins, and Cas9 + guide RNAs. Students express colorful proteins in the extract & then use CRISPR to cut the protein-coding genes, leading to loss of color.
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