Michael Galperin
@MicroGap
Bacterial signaling, c-di-GMP, c-di-AMP, protein domains NCBI's Comp. Bio. Branch, COG database, J. Bacteriology
Potrebbero piacerti
I can't believe what I've just watched. A Jewish lawyer wearing a Star of David was arrested after the police alleged the symbol had "antagonised" pro-Palestine protesters. He was handcuffed and detained by police for almost TEN hours. DISGUSTING! Shame on you @metpoliceuk.
A new kind of magic mushroom: Two fungal genera use two distinct pathways to synthesize psilocybin onlinelibrary.wiley.com/doi/full/10.10…
onlinelibrary.wiley.com
Dissimilar Reactions and Enzymes for Psilocybin Biosynthesis in Inocybe and Psilocybe Mushrooms
Mushrooms have learned twice independently how to make the iconic magic mushroom natural product psilocybin. This article introduces the enzymes of the second pathway, found in a fiber cap mushroom....
FWIW: New mechanisms for bacterial motility and DNA transfer between bacteria decoded, via @EurekAlert! eurekalert.org/news-releases/…
Over two years in the making, but here it is: ComFB, the third family of c-di-GMP receptor proteins with representatives in multiple bacterial phyla (PMID: 40966295) doi.org/10.1073/pnas.2…
Analysis of essential genes in Clostridioides difficile by CRISPRi and Tn-seq | Journal of Bacteriology journals.asm.org/doi/10.1128/jb…
Some thoughts on metabolism and metabolic pathway holes pnas.org/doi/10.1073/pn….
Lara Amorim, Conceição Santos and Kenneth Timmis Prioritising Microbiology in Secondary Education Addresses Emerging Scientific-Social-Educational Challenges and Competency Needs …icro-journals.onlinelibrary.wiley.com/doi/10.1111/17…
Incredible! Fascinating piece by Elisabeth Bik @MicrobiomDigest Discontinuous ridiculous stools – a preprint full of tortured phrases and stolen data scienceintegritydigest.com/2025/07/28/dis… h/t @RetractionWatch
scienceintegritydigest.com
Discontinuous ridiculous stools – a preprint full of tortured phrases and stolen data
“Patients with provocative entrail illness unclassified gave to crisis division a 3-day history of sickness, retching, migraine and irregular stomach torment alongside discontinuous ridiculous stoo…
The interactions of c-di-GMP with the acidic residues seen in the MshEN domain could be quite widespread onlinelibrary.wiley.com/doi/10.1002/an… Protonated Glutamate and Aspartate Side Chains Can Recognize Phosphodiester Groups via Strong and Short Hydrogen Bonds in Biomacromolecular Complexes
An interesting discussion: c-di-GMP does not bind H-NS, nor inhibits H-NS binding DNA | Nat. Comm nature.com/articles/s4146… (PMID: 40506437) Reply to: “c-di-GMP does not bind H-NS, nor inhibits H-NS binding DNA” | Nat. Comm nature.com/articles/s4146… (PMID: 40506445)
Lee Kroos et al. (17 authors) From the humblest of beginnings (i.e. a pile of dry cow dung) over 80 years ago, the Gram-negative bacterium Myxococcus xanthus has emerged as a premier model system for studying diverse fields of bacteriology journals.asm.org/doi/full/10.11…
Very happy to share that a large part of my thesis work is out today: B. subtilis uses the second messenger c-di-AMP to modulate its turgor pressure in response to the state of its cell envelope. nature.com/articles/s4156…
In the architecture of the outer membrane complex PelBC for Pel export, the essential periplasmic ring of twelve PelC lipoproteins is mounted on top of the PelB β-barrel nature.com/articles/s4146…
In Bacillus subtilis, c-di-AMP levels are modulated by the cyclase regulator CdaR in response to cell wall defects. Great work by @apbrogan.bsky.social et al. nature.com/articles/s4156…
This paper offers a solution to a long-standing problem: A general mechanism for initiating the bacterial general stress response | eLife @nielsbradshaw doi.org/10.7554/eLife.…
We cracked the mystery: Pteridines are the natural ligands of CutA, a widespread protein in nature @HHU_de @CoE_CMFI I started this project 8y ago. We showed that it's of PII signaling family, but it's role remained unknown coz we didn't know what it bind biorxiv.org/content/10.110…
Congratulations, @shuramankin! nature.com/articles/s4158…
Congratulations to my former postdoc supervisor, Prof. George Salmond. A well-deserved recognition! @MicrobioSoc microbiologysociety.org/news/society-n…
I know one thing. Zelenskyy would’ve received a hero’s welcome from these guys, and sent home with enough ammo to go all the way to Moscow.
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