NAPLEX Study Guide
@NAPLEXTestStudy
Study and pass the 2026 NAPLEX exam and become a professional, qualified pharmacist in the United States. Future pharmacists train with us.
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💊NAPLEX MedFact. Streptokinase is a fibrinolytic agent produced by streptococcal bacteria, and because of its bacterial origin, the body can form antibodies against it after initial exposure. ☑️If the drug is administered again within 6 – 12 months, these circulating…
💊NAPLEX MedFact. Allopurinol is used in cancer therapy primarily for the prevention and management of hyperuricemia associated with tumor lysis syndrome (TLS). ☑️TLS occurs when cancer cells, particularly in rapidly proliferating malignancies such as leukemias and lymphomas,…
FDA Approves Kygevvi (doxecitine and doxribtimine) for the Treatment of Thymidine Kinase 2 Deficiency drugs.com/newdrugs/fda-a…
💊NAPLEX MedFact. Ziconotide is a non-opioid analgesic derived from a synthetic version of a peptide found in the venom of the marine cone snail Conus magus. ☑️It works by selectively blocking N-type voltage-sensitive calcium channels on nerve cells in the spinal cord, thereby…
💊NAPLEX MedFact. Prominent examples of CYP 3A4 inhibitors include: ☑️macrolides ☑️azole antifungals ☑️calcium channel blockers ☑️protease inhibitors ☑️amiodarone ☑️grapefruit juice
💊NAPLEX MedFact. 1⃣What is zanidatamab? Zanidatamab is a bispecific monoclonal antibody used in the treatment of HER2-positive biliary tract cancer. 2⃣How does it work? It works by binding to two non-overlapping epitopes on the HER2 receptor, causing receptor clustering and…
💊NAPLEX MedFact. Hartmann’s solution — also known as compound sodium lactate — is an isotonic crystalloid fluid designed to closely mimic the electrolyte composition of plasma. It contains: ☑️sodium chloride (NaCl) ☑️sodium lactate ☑️potassium chloride (KCl) ☑️calcium…
💊NAPLEX MedFact. Many drugs can prolong the QT interval. Some of the most widely implicated include: ☑️macrolides ☑️fluoroquinolones ☑️antipsychotics ☑️quinine / hydroxychloroquine ☑️SSRIs
Gene Test Can Predict Risk For Gout Medicine, Allopurinol, Side Effects drugs.com/news/gene-test…
💊NAPLEX MedFact. Dopamine agonists — particularly those with high affinity for D3 receptors such as pramipexole and ropinirole — are strongly linked to the development of impulse control disorders (ICDs), including hypersexuality, pathological gambling, and compulsive shopping.…
💊NAPLEX MedFact. Pirfenidone is an antifibrotic and anti-inflammatory drug used primarily in the treatment of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung disease characterized by scarring of lung tissue. ☑️It works by inhibiting key pathways involved…
💊NAPLEX MedFact. Dosage information for eszopiclone. Usual adult dose in the treatment of insomnia: ☑️Initial dose: 1 mg orally once daily at bedtime, immediately before going to bed. ☑️Dose adjustment: The dose may be increased if clinically necessary, based on both…
💊NAPLEX MedFact. Ropinirole, a dopamine agonist used in Parkinson’s disease and restless legs syndrome, can cause several important side effects related to dopaminergic stimulation. ☑️Common adverse effects include nausea, dizziness, somnolence, orthostatic hypotension, and…
💊NAPLEX MedFact. Penicillins can increase methotrexate toxicity by reducing its renal tubular secretion, leading to higher plasma concentrations and increased risk of adverse effects such as myelosuppression and mucositis. ☑️The interaction is most clinically significant with…
💊NAPLEX MedFact. Fibrinolytic drugs (also known as thrombolytics) act by promoting the conversion of plasminogen to plasmin, the enzyme responsible for breaking down fibrin clots. ☑️Plasmin degrades the fibrin meshwork within a thrombus, dissolving the clot and restoring blood…
💊NAPLEX MedFact. Andexanet alfa is a recombinant modified human factor Xa decoy protein used as a specific reversal agent for factor Xa inhibitors such as apixaban and rivaroxaban in cases of life-threatening or uncontrolled bleeding. ☑️It works by binding and sequestering…
Some Antidepressants Linked to Weight, Heart Health Changes drugs.com/news/some-anti…
💊NAPLEX MedFact. Drug treatment of Lyme disease depends on the stage of infection and clinical manifestations. ☑️For early localized disease (e.g. erythema migrans), the first-line therapy is doxycycline 100 mg twice daily for 10 – 21 days in adults, as it effectively covers…
💊NAPLEX MedFact. Azathioprine interacts with the anti-gout drug, allopurinol. ⚙️Mechanism: allopurinol inhibits xanthine oxidase, the enzyme responsible for metabolizing azathioprine’s active metabolite (6-mercaptopurine). ⚠️Effect: this greatly increases azathioprine levels,…
💊NAPLEX MedFact. A persistent, dry cough with ACE inhibitors occurs due to the accumulation of bradykinin and substance P in the respiratory tract: ☑️Normally, the enzyme angiotensin-converting enzyme (ACE) breaks down these substances, but ACE inhibitors block this process.…
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