Overacre Lab
@OveracreLab
Assistant Professor @UPMCHillmanCC | @DamonRunyon Dale Frey Scientist | microbiome & immunotherapy | follow your gut | she/her/hers | views are my own
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I am thrilled to finally share my lab's first paper showing that sucralose consumption reduces immunotherapy efficacy in cancer, published NOW in @CD_AACR ! Let's break it down. 1/n aacrjournals.org/cancerdiscover…
When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018. Read more on #STEMSTEAMDay: scim.ag/48YwNzI @NewsfromScience
Loved participating!
Grateful to everyone who joined our Hill visits this week advocating for stronger support of biomedical research. Your efforts to champion increased NIH funding help drive discovery and improve lives. #SITContheHill
The November issue of @CD_AACR is now online! The cover features work by @diwakardavar, @OveracreLab, and colleagues providing evidence that sucralose consumption ablates cancer immunotherapy response through microbiome disruption - read that and more: aacrjournals.org/cancerdiscover…
Science is not a contest to be won. It’s a collective pursuit of truth that evolves with evidence - not a debate settled by opinion or the loudest voice.
Regulatory T cells, the immune cells at the centre of Monday's Nobel Prize, are showing promise as a treatment for autoimmune diseases, cancer, and even organ transplants go.nature.com/3WqNNab
Cheers to the best cell! #Tregs
BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
Had a great time sharing our work on irAEs and the microbiome at @AACR today! Listening in to a fantastic panel of experts on the evolving needs in this space.
Tylenol, or paracetamol, has been used to treat common pains and fevers since 1893, and is one of the safest drugs around go.nature.com/3W6aHU8
We have people in power making broad claims around certain drugs and autism that have been continuously disproven. The degree to which those comments can undermine public health, do harm to women who are pregnant, create anxiety for parents who do have children who are autistic –…
Extremely honored to receive the @UPMCHillmanCC Emerging Scholar Award this year. Even more excited to see one of my exceptional PhD students, Kelsey Ertwine, win the Director’s Award for her research on the microbiome and Tregs in cancer!
When your trainees start to master techniques and analyses that you don't know how to do... #proudPI
Thanks to @TheScientistLLC for covering our article in @CD_AACR on sucralose impacting immunotherapy! Also, thanks to Jotham Suez for the commentary! Exciting things to come! the-scientist.com/a-common-artif…
ICYMI: Good news! The House rejected the proposed 40% NIH funding cut. The bill released has NIH funded at $48 billion, almost identical to the Senate’s number of $48.7 billion.
(Please RT/like/share) We are hiring for the lab @VersitiResearch! Technologist I/II ads live and capacity for a postdoc. For all those who love tissue-resident immunity! Please feel free to reach out or to recommend a colleague. (Not posting links here to avoid spam)
Check it out!
Now online in @CD_AACR: Sucralose Consumption Ablates Cancer Immunotherapy Response through Microbiome Disruption - by @itstherealKM, Madison Nguyen, Drew Wilfahrt, @diwakardavar, @OveracreLab, and colleagues doi.org/10.1158/2159-8… @UPMCHillmanCC @PittTweet
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