Perlara
@PerlaraPBC
http://perlara.com The first biotech public benefit corporation (est. 2014) now developing medicines for inherited metabolic diseases (MITO, CDG)
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⚡️BIG NEWS⚡️ We were awarded a $1.7M SBIR grant to scale up a yeast-powered mitochondrial disease pipeline! This represents a major milestone/turning point for the company. It’s the beginning of Perlara 3.0 with a focus on developing medicines for inherited metabolic diseases.
The evolution of biotech company Perlara 1.0 = B2B platform as a service <pivot> Perlara 2.0 = DTC platform as a service <pivot> Perlara 3.0 = DTC drug developer
⚡️BIG NEWS⚡️ We were awarded a $1.7M SBIR grant to scale up a yeast-powered mitochondrial disease pipeline! This represents a major milestone/turning point for the company. It’s the beginning of Perlara 3.0 with a focus on developing medicines for inherited metabolic diseases.
Perlara absolutely is interested in using many screening setups to connect drugs to diseases! This is a type they currently don’t use, protein localization in cultured human cells, but could. We are discussing in DMs actually whether they’d adopt the project, maybe STTR 😄
Restoring Balance To The Flux CDGs are a 200+ gene family of inherited metabolic diseases, GMPPA-CDG and SRD5A3-CDG to name a few. Turns out GMPPA deficiency is rescued by SRD5A3 deficiency 🤯. Two genetic wrongs can make a right.
Do you love the movie - Hackers? Of course you do. Maybe you'll enjoy this story too. "She Found the Backdoor - One Mom’s Hack on Genetic Diagnosis w/ Julia Taravella" I met Julia Taravella in a Seattle coffee shop in 2022, after she messaged me while she was in town from…
A little girl in Hong Kong with the rare genetic disease PIGN-CDG has been seizure-free for a year while taking ascorbyl palmitate aka fat-soluble Vitamin C. Still blows my mind everytime I hear case reports like this, especially because we went straight from a yeast hit in the…
Anyone who says DeSci is a scam is jaded by short termism and has lost the values that created Bitcoin and Ethereum. Solving long term problems for real people. @bioprotocol first BioDAO on Solana is by Harvard alumni and biotech legend @eperlste who has dedicated his life to…
Let’s go parabolic in the final 24 hours of the $CURES auction 📈 $520,000 raised so far despite the market sentiment 💪 Max target is $3M 🎯
🤯 Rare Diseases = $1T+ market ♻️ Drug Repurposing is the training set for AI Drug Discovery 💊 Medicines are within reach 🚶Kiddos are taking their first steps 👀 Just watch the before vs after reel 🚀 Turn crypto into $CURES moonshots 🚨 AUCTION CLOSES IN 24 HOURS
CDG CARE is kicking off a new chapter with a brand-new Core Team and updated 2025 Board roles. Our passionate leaders are set to drive innovation and strengthen our CDG community. Congrats to our inspiring team!
Happy Darwin Day! Today we’re thinking about how to use evolution to accelerate biomedical research. We think the answer is to expand the repertoire of organismal models. Search for the best ones using our new portal Zoogle: zoogle.arcadiascience.com/about 🧵
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis…
Wow! Incredible working coming from @PerlaraPBC and @endrarediseases ! Incredible Presentation! @cure4ars #rarediseaseday
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