Schmidt_Lab_USF's profile picture. Deciphering molecular mechanisms of genome instability in human cells and yeast. Bloom syndrome & BLM, DNA replication & repair, disordered protein function.

Kristina Schmidt

@Schmidt_Lab_USF

Deciphering molecular mechanisms of genome instability in human cells and yeast. Bloom syndrome & BLM, DNA replication & repair, disordered protein function.

Kristina Schmidt reposted

The USF Health Morsani College of Medicine is the highest ranked medical school in the country and the only school to receive a perfect score of 100 in a new Medical Excellence Index ranking released Wednesday by a national medical policy group. Learn more:…

USFHealth's tweet image. The USF Health Morsani College of Medicine is the highest ranked medical school in the country and the only school to receive a perfect score of 100 in a new Medical Excellence Index ranking released Wednesday by a national medical policy group. Learn more:…

Kristina Schmidt reposted

Stunning sunset views over Tampa Bay this evening! #FLwx

Stunning colors displayed throughout Spring Hill this evening. @NWSTampaBay @mcclureWX @bn9weather @spann #Flwx

baja_noah's tweet image. Stunning colors displayed throughout Spring Hill this evening. @NWSTampaBay @mcclureWX @bn9weather @spann #Flwx
baja_noah's tweet image. Stunning colors displayed throughout Spring Hill this evening. @NWSTampaBay @mcclureWX @bn9weather @spann #Flwx
baja_noah's tweet image. Stunning colors displayed throughout Spring Hill this evening. @NWSTampaBay @mcclureWX @bn9weather @spann #Flwx
baja_noah's tweet image. Stunning colors displayed throughout Spring Hill this evening. @NWSTampaBay @mcclureWX @bn9weather @spann #Flwx


Kristina Schmidt reposted

🍂The 2025 Fall Session of GIIN webinars is here! Join us on the 1st Tuesday of each month at 5 PM CET (Rome) / 11 AM DET (NYC). No pre-registration needed, just click to join via Zoom: uniroma1.zoom.us/j/95149984403 Subscribe here for webinar reminders: docs.google.com/forms/d/e/1FAI…

GenomeIINetwork's tweet image. 🍂The 2025 Fall Session of GIIN webinars is here! 
Join us on the 1st Tuesday of each month at 5 PM CET (Rome) / 11 AM DET (NYC). No pre-registration needed, just click to join via Zoom:  uniroma1.zoom.us/j/95149984403
Subscribe here for webinar reminders:  docs.google.com/forms/d/e/1FAI…

Kristina Schmidt reposted

Direct detection of 8-oxo-dG using nanopore sequencing. #DNAmodifications #Nanopore #Sequencing @nanopore @NatureComms nature.com/articles/s4146…

jsantoyo's tweet image. Direct detection of 8-oxo-dG using nanopore sequencing. #DNAmodifications #Nanopore #Sequencing @nanopore @NatureComms 
nature.com/articles/s4146…

In our latest paper, we uncover condensin II as a novel BLM interactor critical for genome stability in S phase. Condensin II contributes to BLM localization at active forks and undergoes a transient structural change in S phase.nature.com/articles/s4200…


Kristina Schmidt reposted

Are you ready the 2nd half of 2025? Social DNAing is! Checkout who is coming to Social DNAing! Sign up at cancer.columbia.edu/research/progr…. Please re-twitte

zha_lab's tweet image. Are you ready the 2nd half of 2025? Social DNAing is! Checkout who is coming to Social DNAing! Sign up at 
cancer.columbia.edu/research/progr…. Please re-twitte

Kristina Schmidt reposted

BREAKING NEWS: The @USFHealth Morsani College of Medicine is the #1 medical school in Florida — and the only program in the state to earn a Tier 1 ranking from @usnews. This places @USouthFlorida among the Top 16 medical schools nationwide.🤘#GoBulls ➡️ bit.ly/MCOMranking

USFHealthMed's tweet image. BREAKING NEWS: The @USFHealth Morsani College of Medicine is the #1 medical school in Florida — and the only program in the state to earn a Tier 1 ranking from @usnews. This places @USouthFlorida among the Top 16 medical schools nationwide.🤘#GoBulls

➡️ bit.ly/MCOMranking

Kristina Schmidt reposted

Our new preprint is now on bioRxiv! 📄 We introduce qAID, an AI-based workflow for automated analysis of DNA replication dynamics. Glad to have contributed a small part to this study.

Quantitative AI-based DNA fiber workflow to study replication stress biorxiv.org/content/10.110… #biorxiv_cellbio



Kristina Schmidt reposted

Osteosarcoma, an aggressive bone cancer, most commonly affects children and young adults. New research solves the mystery of what drives the genomic rearrangements causing the aggressive development and evolution of osteosarcoma tumours. ebi.ac.uk/about/news/res…

emblebi's tweet image. Osteosarcoma, an aggressive bone cancer, most commonly affects children and young adults.

New research solves the mystery of what drives the genomic rearrangements causing the aggressive development and evolution of osteosarcoma tumours.

ebi.ac.uk/about/news/res…

Kristina Schmidt reposted

RAD52 dominates DNA repair at #centromeres over RAD51 & NHEJ's factors, leading to apoptotic cell death. Centromeric DSBs reveal nuanced repair pathway choices. #genomics #research PMID:39360606, Nucleic Acids Res 2024, @NAR_Open buff.ly/4f7vVIx


Kristina Schmidt reposted

2/2 To learn more about our lab see our homepage: ochslab.org We are an international, multidisciplinary lab focussed on genome stability maintenance & 3D chromatin. Happy to be contacted with any questions you might have about this job. / Fena


Kristina Schmidt reposted

1/2 We’re hiring a Postdoc to join us at the University of Copenhagen. Are you fascinated by 3D chromatin function and super-resolution microscopy? Then this might be the job for you. Start date 1st of April 2025, starting salary 4700 Euro/month. candidate.hr-manager.net/ApplicationIni…

candidate.hr-manager.net

Postdoctoral Research Associate in the Ochs Group at the Biotech Research & Innovation Centre (BRIC)

Postdoctoral Research Associate in the Ochs Group at the Biotech Research & Innovation Centre (BRIC)


Kristina Schmidt reposted

📣 Excited to share our latest review on 53BP1’s function in replication stress, its role in fork protection, and the significance of 53BP1 nuclear bodies in this context! sciencedirect.com/science/articl…

ChowdhuryLab's tweet image. 📣 Excited to share our latest review on 53BP1’s function in replication stress, its role in fork protection, and the significance of 53BP1 nuclear bodies in this context! 

sciencedirect.com/science/articl…

Kristina Schmidt reposted

Our study on how the human MCM2-7 helicase is loaded onto replication origins 🧬 is now online @Nature! 🎉 Our findings reveal that unlike in yeast, human MCM loading does not require ORC6 and can occur through multiple pathways. Read more here: rdcu.be/d1F6S


Kristina Schmidt reposted

Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳 Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! rdcu.be/d1F7m

CostaLabCrick's tweet image. Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳  

Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors!   rdcu.be/d1F7m

Kristina Schmidt reposted

The spindle assembly checkpoint in #yeast has been implicated in promoting large chromosomal arrangements, which can cause cancer. A new #GENETICS study revisits this observation, finding it originated from an experimental artifact & does not hold true. bit.ly/3Nc7NJe

GeneticsGSA's tweet image. The spindle assembly checkpoint in #yeast has been implicated in promoting large chromosomal arrangements, which can cause cancer.

A new #GENETICS study revisits this observation, finding it originated from an experimental artifact & does not hold true.

bit.ly/3Nc7NJe

Kristina Schmidt reposted

Assistant and Associate Professor positions available at UPENN's Basser Center for BRCA . Great opportunity to be part of an amazing scientific environment. Assistant Level:  apply.interfolio.com/155257 Associate Level : apply.interfolio.com/155258


Kristina Schmidt reposted

Thrilled to share our new work @biorxivpreprint: biorxiv.org/content/10.110… Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live cells. We reveal genome chromatin is essentially replicated from regions with greater nucleosome motions. 1/2


Kristina Schmidt reposted

The 2024 Nobel Prize in Physiology or Medicine has been awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation.” Nature Portfolio presents this Collection to celebrate the award. go.nature.com/4eA5Nq2

NaturePortfolio's tweet image. The 2024 Nobel Prize in Physiology or Medicine has been awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation.” Nature Portfolio presents this Collection to celebrate the award. go.nature.com/4eA5Nq2

Kristina Schmidt reposted

Crossing the border: Replication fork adducts move to lysosomes for autophagic repair dlvr.it/TFYyjJ

MolecularCell's tweet image. Crossing the border: Replication fork adducts move to lysosomes for autophagic repair dlvr.it/TFYyjJ

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