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Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology - Molecular Oncology febs.onlinelibrary.wiley.com/doi/10.1002/18…
📣Abstract Deadline Extended‼️ Submit your abstracts by our new deadline Tuesday, 22nd April, 9AM AEST. It's a new race to the finish line for your abstract writing, don't miss your chance to connect with the brilliant cancer bioinformatics community in Australia and overseas.
Reprogramming of Androgen Receptor Activity in Castration-resistant Prostate Cancer is Shaped by Truncated Variants - European Urology Focus eu-focus.europeanurology.com/article/S2405-… @PeterMacRes @LukeSelth @ReneaTaylor1
Co‐targeting BET, CBP, and p300 inhibits neuroendocrine signalling in androgen receptor‐null prostate cancer - Choo - The Journal of Pathology - Wiley Online Library …thsocjournals.onlinelibrary.wiley.com/doi/10.1002/pa… @PeterMacRes @MonashPCCC @ReneaTaylor1 @PCR_News @dl_goode @PeterMacCC
📢 Abstract submissions are still open for the Cancer Bioinformatics Australia symposium (Deadline: Friday 26th April 2024)! Share your groundbreaking research and join us in advancing cancer bioinformatics cancerbioinformatics.au #CancerBioinformatics #Research #Symposium
Defining focal neuroendocrine differentiation as a transcriptionally distinct form of prostate cancer pathology characterized by the expression of androgen receptor @PeterMacRes @ReneaTaylor1 @dl_goode biorxiv.org/content/10.110…
Thrilled to be awarded a @nhmrc Synergy Grant with this dynamic and talented team 👇🏻👇🏻👇🏻
Congrats 👏to CIs @monashuni Gail Risbridger @reneataylor1 Daniela Loessner @3dcancergroup @prof_iand, @garvaninstitute @paultimpson7, @petermaccc Phil Darcy, for @nhmrc $5m #synergy grant to develop #CARTcell #immunotherapies for #ProstateCancer. Read: bit.ly/46Zid7g
I am taking effort to raise funds for Movember for men's mental health, suicide prevention andProstate Cancer I'm growing a Mo and would like your support to kick start my fund raising event. @ReneaTaylor1 @PMPostdocs @PeterMacRes #Movember URL: movember.com/m/14188465?mc=1
Here's a good read! Researchers at @UniMelb assessed the efficacy of Lewis Y antigen-specific CAR T cells in patient-derived xenograft models of prostate cancer. Learn more here ⬇️
A team at @UniMelb including Drs. Gail Risbridger and Renea Taylor report that low-dose carboplatin modifies the tumor microenvironment to augment #CART cell efficacy in human #ProstateCancer models. go.nature.com/3L9Xogo
3. Pre-treatment with low-dose carboplatin chemotherapy greatly enhances CAR T cell potency, including early and persistent infiltration of activated T cells, resulting in complete tumor regression
1. CAR T cells directed to Lewis Y – an onco-foetal glycolipid antigen - was an unexpected target for prostate cancer, with minimal expression in normal tissues, but expressed in 12% of localized, 20% of metastatic and 57% of aggressive prostate tumors
6. We are still searching for the ideal #TME modulating agents that lead to a response to CAR T cell immunotherapy for most prostate tumors. Watch this space!
Can carboplatin treatment facilitate CAR T cell retention and the sustained response to LeY CAR T cells? @PMPostdocs,@PeterMacRes,@MonashPCCC,@ReneaTaylor1 nature.com/articles/s4146…
nature.com
Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human...
Nature Communications - Although CAR T therapy has greatly improved the therapeutic prospects for haematological malignancies, it is not yet widely used for solid tumors, such as prostate cancer....
See our latest publication in @NatureComms on prostate cancer CAR T cell efficacy. Preclinical studies provide proof of concept that modifying the #TME enhances T cell trafficking and activation @MonashBDI @PeterMacRes #prostatecancer #CARTcells rdcu.be/dk0Ss
Another week, another #onjcri award winner. Congrats @DmelloRhynelle for being awarded the 2023 ONJCRI Student Medal👏 Read more about her #cancerresearch into improving the efficacy of #colorectalcancer treatments: linkedin.com/feed/update/ur… #phdlife #researcher #studentaward
Donate to help me raise much-needed funds for #menshealth this #Movember – for all the dads, brothers, sons and mates in our lives. Stop men dying too young. movember.com/m/14188465?mc=6
Fungal DNA, Cells Found in Human Tumors the-scientist.com/news-opinion/f…
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