Silberstein_Lab's profile picture. We are a hematopoiesis lab @FredHutch investigating the behavior of healthy and malignant hematopoietic stem cells

Silberstein Lab

@Silberstein_Lab

We are a hematopoiesis lab @FredHutch investigating the behavior of healthy and malignant hematopoietic stem cells

Silberstein Lab reposted

This @NatureGenet study screened for somatic mutations in healthy aged individuals, identifying expanded HSC clones accessible for lineage tracing of all major blood cell lineages. 🩸 ✅ Check it out! go.nature.com/3LC2rcH

Hema_News's tweet image. This @NatureGenet study screened for somatic mutations in healthy aged individuals, identifying expanded HSC clones accessible for lineage tracing of all major blood cell lineages. 🩸

✅ Check it out! 
go.nature.com/3LC2rcH
Hema_News's tweet image. This @NatureGenet study screened for somatic mutations in healthy aged individuals, identifying expanded HSC clones accessible for lineage tracing of all major blood cell lineages. 🩸

✅ Check it out! 
go.nature.com/3LC2rcH

Silberstein Lab reposted

Thrilled to share our work on the role of taurine in myeloid leukemia progression in @nature today! nature.com/articles/s4158…

Jeevisha_Bajaj's tweet image. Thrilled to share our work on the role of taurine in myeloid leukemia progression in @nature today! nature.com/articles/s4158…

Thank you to the wonderfully talented Rioka Hayama riokahayama.com for blending the senior author’s two passions - classical music and biology - to capture the essence of our paper nature.com/nataging, and to Nature Aging editors for choosing it as the cover art.

Silberstein_Lab's tweet image. Thank you to the wonderfully talented Rioka Hayama riokahayama.com for blending the senior author’s two passions - classical music and biology - to capture the essence of our paper nature.com/nataging, and to Nature Aging editors for choosing it as the cover art.

How do hematopoietic stem cells resist inflammatory damage and do not age prematurely? Turns out that Semaphorin 4A-producing neutrophils come to rescue, as we report in our first paper, out in Nature Aging rdcu.be/d7UvQ. Cudos to 36 coauthors, reviewers and NA editors!


Silberstein Lab reposted

Out today in @NatureBiotech! PhD students & postdocs: there's a trick – overlooked and underused – for having new ideas in the creative process. Talk science 1 on 1 with a science buddy that you trust and think of it as an improvisation. nature.com/articles/s4158…@MartinJLercher

ItaiYanai's tweet image. Out today in @NatureBiotech! PhD students & postdocs: there's a trick – overlooked and underused – for having new ideas in the creative process. Talk science 1 on 1 with a science buddy that you trust and think of it as an improvisation. nature.com/articles/s4158……
@MartinJLercher

We are looking for a technician and a post-doc. If you know anyone who's interested in pre-leukemia/inflammation/the niche and enjoy exploring nature, please ask to RT or email [email protected]. Thank you!


Truly wonderful to reconnect with old colleagues and meet new ones at Mol Haematopoiesis meeting in London. Thank you for the opportunity to hear tremendous speakers and present our data, and to Doug Higgs for his inspirational advice "to enjoy every day of doing science".


We are looking for a new Technician colleague to study the biology of HSC and their niches in inflammation, pre-leukemia and aging. Will fully support anyone who is interested in becoming a leader for their project. DM/email [email protected] to explore this opportunity.


We currently have two post-doctoral positions for those interested in studying how niche factors can be converted into drugs to prevent leukemic evolution and inflammation-induced HSC damage. Please DM or email [email protected] to find out more!


Grateful and honored to have our MDS work now supported by @EdwardPEvansFdn Discovery grant! Thank you to @edie_crosse and others in the @Silberstein_lab for input and preliminary data. Look forward to working with @StanleyCLee, @JShendure and @SteidlUli on this exciting project!


Seminal study for all of us in the MDS field: evidence.nejm.org/doi/full/10.10…


Silberstein Lab reposted

We are excited to host @Silberstein_Lab from Fred Hutchinson Cancer Center for an exciting seminar!

Einstein_SCI's tweet image. We are excited to host @Silberstein_Lab from Fred Hutchinson Cancer Center for an exciting seminar!

Our first paper is now online. Who knew that a semaphorin from the niche offers a special protection to myeloid-biased HSC? Grateful all contributors, with special thanks to @anto_scial (single cell analysis) and @JoelSpencerLab (intra-vital imaging). biorxiv.org/content/10.110…


Proud to see our post-doc Edie Crosse in this group! Delighted to announce our newest class of Damon Runyon Fellows! We're honored to award seventeen remarkable postdoctoral scientists with independent funding to kickstart their research careers: bit.ly/3yBfHmr


Silberstein Lab reposted

Delighted to announce our newest class of Damon Runyon Fellows! We're honored to award seventeen remarkable postdoctoral scientists with independent funding to kickstart their research careers: bit.ly/3yBfHmr


Silberstein Lab reposted

We’re still evaluating and interviewing candidates for these postdoctoral funding schemes. You can still apply!!!!

Siguen abiertas las convocatorias para la atracción y retención de talento científico: Ramón y Cajal 🗓️21/1 ➡️bit.ly/3mD0Kdv Juan de la Cierva - incorporación 🗓️19/1 ➡️bit.ly/3mCDts3 Juan de la Cierva - formación 🗓️21/1 ➡️bit.ly/3mN2alC

CienciaGob's tweet image. Siguen abiertas las convocatorias para la atracción y retención de talento científico:

Ramón y Cajal
🗓️21/1
➡️bit.ly/3mD0Kdv

Juan de la Cierva - incorporación
🗓️19/1
➡️bit.ly/3mCDts3 

Juan de la Cierva - formación
🗓️21/1
➡️bit.ly/3mN2alC


After a promising score back in June, our first R01 is finally here. Grateful for an opportunity to learn more about myeloid-biased HSC and their regulation by the niche. Happy to welcome those who’re interested in joining us on this journey.


We are pleased that our new postdoc @edie_crosse has had her PhD work published @CellStemCell, online now. #stemcells #hematopoiesis

Very proud to present my PhD work published @CellStemCell. A spatial profile of human blood development! Huge thanks to Alexander and the rest of the Medvinsky lab @crm_edinburgh and all other contributors. cell.com/cell-stem-cell…



We're hiring!

The @Silberstein_Lab at @FredHutch is hiring a Lab Aide - great opportunity to get some lab experience. Feel free to share far and wide, and feel free to ping me for more details. social.icims.com/viewjob/pt1600…



The Silberstein Lab are on twitter! We look forward to engaging with the twitter science community and sharing our work with you. #StemCells #CancerResearch #Leukemia


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