Alexander Titz
@Titz_Lab
Nature enthusiast, Professor of Chemistry/Saarland Uni and group lead at HIPS, wheelchair-bound. Views are my own. https://bsky.app/profile/titzlab.bsky.social
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Seems like this place gets stranger and stranger. Chemtwitter is mute and most of my new followers are bots 🙄 See you at the other side 🦋 bsky.app/profile/titzla…
Hey @elonmusk - stay out of it - it's not your business It's our country - You have absolutely no idea - if anyone is an expert on fascism, it's us - shuffle off and go play with your rockets.
I am very proud to share a long story on lectins and biofilm imaging just published in @JACS_Au by Eva and Lisa in cooperation with many colleagues such as @AnneImberty @SueSK001 😍 #glycotime #chembio #AMR please have a look here: pubs.acs.org/doi/10.1021/ja…
pubs.acs.org
High-Affinity Lectin Ligands Enable the Detection of Pathogenic Pseudomonas aeruginosa Biofilms:...
Pseudomonas aeruginosa is a critical priority pathogen and causes life-threatening acute and biofilm-associated chronic infections. The choice of suitable treatment for complicated infections...
Thank you @Dhritirajbastav for the vivid discussion after my talk and at your poster in Amritsar! Good luck with all your enzymology experiments!
Participants of the Indo-German Meeting #ECBS-2024 at Le Meridien Amritsar, coinciding with 50 years India and Germany S&T cooperation. Anticipating complex multidisciplinary science, involved interactions and useful collaborations. @INDOGSTC @GermanyinIndia
It was a great honor for me to kick off the scientific sessions of this great meeting! Big thanks to @Sandeep_1966 and the organizers! #ECBS #Amritsar
Glycotime in infection 😍
Our new paper describing the structure, function, and antigenicity of the Blood Group A-specific lectin, EtpA, from ETEC is out in #PLOSPathogens dx.plos.org/10.1371/journa… Tons of exciting #glycotime results!
In a joint project with @HirschLab we have developed molecules that block two bacterial virulence factors in Pseudomonas infections. The new compounds were superior over combinations of single LecA and LasB blockers. #AMR #glycotime now in @ChemicalScience pubs.rsc.org/en/Content/Art…
We were having an amazing time, discussing science and meeting friends at ICS2024 thanks to Prof. Biao Yu 🥰 On top, Qiuyu won the poster prize 👍
AlphaFold2 and RoseTTAFold are limited to predicting the 3D structure of proteins. A new all-atom method models complete biomolecular assemblies, including proteins, nucleic acids, small molecules, metals, and covalent modifications. #NBThighlight science.org/doi/10.1126/sc…
The antibiotic drug candidate Zosurabalpine, belongs to a new family of antibiotics. On mice studies it showed effectiveness against Acinetobacter baumannii pneumonia (a very problematic and resistant bacteria). nature.com/articles/d4158… @SeeFisch dlvr.it/T2wktK
nature.com
A new class of antibiotics is cause for cautious celebration — but the economics must be fixed
Nature - The threat of antimicrobial resistance means that new antibiotics need to be used sparingly. Governments must support their development with a long-term funding plan.
Scientists hail new #antibiotic that can kill drug-resistant bacteria theguardian.com/science/2024/j… Zosurabalpin defeated highly drug-resistant strains of Carbapenem-resistant Acinetobacter baumannii (Crab) in mouse models of pneumonia and sepsis, and was……… dlvr.it/T3XPrp
Congratulations to our colleagues from @Helmholtz_HIPS for obtaining the budget to tackle this new challenge towards new antibiotics!
Leifichemie ist eine tolle Plattform allen Schülern und Schülerinnen die Chemie anschaulich und interessant näher zu bringen! Highly recommended!! 🤩 leifichemie.de
I have less than 1 mg of sample. How can I get an NMR spectrum with a higher signal-to-noise ratio? u-of-o-nmr-facility.blogspot.com/2007/10/i-only… #nmrchat
RIP, Alexey! A few years ago, I was amazed when watching your video on Putin's system. Sadly, he now won a battle. He must not win the war. Crossing my fingers for a free and democratic Russia! youtu.be/T_tFSWZXKN0?fe…
Check out the outstanding @ACSPublications JMC collection of #DrugDiscovery in Germany. The german #MedChem community is very well represented with great Research papers, Perspectives and Drug Annotations. pubs.acs.org/doi/full/10.10…
pubs.acs.org
Journal of Medicinal Chemistry Collection: Drug Discovery in Germany
Journal of Medicinal Chemistry Collection: Drug Discovery in Germany
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