Fern Koay 郭
@_fernace
👩🏼🔬🇲🇾🇦🇺🇺🇲🔬 Scientist in immunology @TheDohertyInst @UnimelbMDHS
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Untangling how γδ T cells kick-start CD8 immunity!
Ever wondered why gamma delta T cells are required for immunity to liver-stage malaria? Spoiler - they make IL-4! @TheDohertyInst @NatImmunol nature.com/articles/s4159…
Someone call a historian, this match is one for the BOOKS 📚 #RolandGarros #sinner #alcaraz
Our third webinar from the AUS/APAC region, will feature Nick Gherardin and Sho Yamasaki. Thursday, June 12th at 17:00 AEST (8:00 London, 16:00 Tokyo). If you'd like to keep up to date, sign up to the mailing list here: cd1mr1.com/cd1-mr1-society
Our second webinar hosted from USA, will be by Laurent Gapin and Antonia Rotolo. Thursday, February 6th at 16:00 GMT (8:00 Pacific, 11:00 Eastern, 1:00 Friday Tokyo) If you haven't join, get updates and link here: cd1mr1.com/cd1-mr1-society
Role for γδ T cell-derived IL-4 in initiating CD8 T cell immunity to Plasmodium doi.org/10.1101/2024.1… @Lynette_Beattie
💪 New immunity research published in the Journal of Experimental Medicine highlights how the body keeps its prompt immune response in check. go.unimelb.edu.au/pgk8 Authors: @_fernace, Prof Dale Godfrey, Dr Calvin Xu @UniMelbMDHS @TheRMH
Selective regulation of IFN-γ and IL-4 co-producing unconventional T cells by purinergic signaling. New study from Calvin Xu, Dale Godfrey, Hui-Fern Koay @_fernace @TheDohertyInst @UnimelbMDHS and colleagues: hubs.la/Q02YLYGN0 #LymphocyteBiology
Sharing our latest work @PNASNews MR1 presents vitamin B6–related compounds for recognition by MR1-reactive T cells We postulate that tumours' increased metabolism of vit B6 leads to elevated levels of pyridoxal and preferential recognition of tumours by pan-cancer T cells see 🧵
We're incredibly stoked and honoured to have Fabio Grassi's commentary on our paper - this work has built on many of his team's findings and body of work, in the nexus of purinergic control of T cell activation and function! 🌟
Grassi @LaStatale discusses new study by Xu, @_fernace et al (hubs.la/Q02YM3m20) which defines NAD-induced cell death via purinergic P2RX7 receptor in type 1 unconventional T cells, particularly intrahepatic MAIT cells pivotal in liver homeostasis hubs.la/Q02YMplz0
Xu, @_fernace et al. @TheDohertyInst reveal that the ARTC2–P2RX7 regulatory axis is a key modulator of unconventional T-cell survival, showing how this pathway selectively influences innate-like, IFN-γ and IL-4 co-producing T cells. hubs.la/Q02YM2N90 #LymphocyteBiology
Such an inspiring morning spent celebrating the 2024 @LOrealAustralia @UNESCO Fellows! For 26 years now, L'Oreal have supported talented females across the globe to shape the future of STEM 🙌 @DrMistyJenkins @LeannTilley @_fernace @ProfJennyGraves
Delighted to share our paper on adipose gd T cells making IL-17 every night for homeostasis, coordinating lipid metabolism after eating @Nature Huge effort by @Akaron0884 & @BrennethS and the team and collaborators to work this out. Aaron's Tweetorial 👇 nature.com/articles/s4158…
A fantastic collaborative Department to work in, on a beautiful campus. Join us!
The Dept. of Molecular Biology at Princeton University invites applications for a tenure-track faculty position at the Assistant Professor level. We seek a colleague who will build a world-class research program in cell biology. For details and to apply: princeton.edu/acad-positions…
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