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Excited to share our preprint about the spatiotemporal dynamics of mammalian #brain aging. With our new map generated at @wysscoray lab, we made a step towards understanding when and how the 🧠 ages! 1/9 biorxiv.org/content/10.110…
Preprint alert! A must read from Oliver Hahn who generated a spatiotemporal gene expression map of 15 brain regions! This study shows that the white matter tracts are an early hotspot of brain aging! Many other cool findings to discover here 👇 biorxiv.org/content/10.110…
Data from NIH-funded studies will have to be shared. This won't be straightforward to implement but that's a huge step for open science 👇
1) On January 25th 2023 a new data sharing policy from NIH kicks in which basically requires raw data from NIH-funded studies to be shared. Data is defined as:
It's time to stop making t-SNE & UMAP plots. In a new preprint w/ Tara Chari we show that while they display some correlation with the underlying high-dimension data, they don't preserve local or global structure & are misleading. They're also arbitrary.🧵biorxiv.org/content/10.110…
@j_n_justice, @blehall and Irene Martinez de Toda will talk about "Involving new blood into #geroscience". Mark your agenda to learn more from these expert leaders at the 2nd @EGeroscience conference. Download our cutting-edge program 👇 bit.ly/3sPzAE7
Our new @NatureAging paper is the direct evidence that we should closely look at the main contributors of aging clocks. In this study led by David Furman, CXCL9 was identified as having a key role in age-related chronic inflammation! nature.com/articles/s4358…
nature.com
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence,...
Nature Aging - From the blood immunome of 1,001 individuals aged 8–96 years, the authors used deep learning to develop an inflammatory clock of aging (iAge) that tracks with multimorbidity,...
Proteomic aging clocks are very intriguing. Read our latest paper in #AgeingResearchReviews in which we show that the aging clock we previously described is a rich source of viable anti-aging drug targets...Still a lot to understand about aging clocks! sciencedirect.com/science/articl…
New research topic in Frontiers in Neuroscience on the links between the blood and brain disorders. Consider submitting a paper! Abstracts are due by May 24 and manuscripts by Nov 23. frontiersin.org/research-topic…
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