
@BrainComms
@braincomms
Brain Communications is the #OA sister journal to @Brain1878. We aim to publish robust translational neuroscience studies.
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If you have read an outstanding paper published in our journal Brain Communications during 2025, ✍️ take note of it for the upcoming Early Career Researcher Paper Prize! Nominations Open Late 2025! #ecr #paperprize #neuroscience 🧠 🧠 🧠

Bosco et al. studied children with apraxia of speech, finding cerebral structural differences in key regions for speech/language and motor tasks. These brain changes correlate with speech severity. Full article 👉 buff.ly/8qF6jU9

Butenko et al. compared simple and advanced approximations of axonal activation considering the uncertainty in fibre diameters. The prominent effect of fibre diameter selection further confirmed the necessity of probabilistic approaches. Full article 👉 buff.ly/hITYNdr

Neurofilament-light-chains are elevated in patients with Friedreich Ataxia compared with controls and remain stable after 1 year follow-up. Results show plasma neurofilament as a good candidate biomarker for future therapeutic intervention. Full report 👉 buff.ly/iErzNFe

Takyi et al. report brain age changes in months following stroke reflecting neurodegeneration. Findings support brain age as a marker of neurodegeneration with potential implications for recovery prediction. 👉 buff.ly/PsJRcvf @most_demigod @Insermu1266 #stroke

Otani et al. estimated motor unit current and showed four current patterns that were much larger in patients with neurogenic disease than in healthy individuals. Full article discussing the findings 👉 buff.ly/b48hbbt

Soussi et al. compared profiles of patients with neurocognitive disorders due to alcohol or Alzheimer’s disease. Cerebellar damage appears specific to alcohol-related disorders. This underscores how one aetiology may mask the other. Full article 👉 buff.ly/di7KIkB

If you have read an outstanding paper published in our journal Brain Communications during 2025, ✍️ take note of it for the upcoming Early Career Researcher Paper Prize! Nominations Open Late 2025! #ecr #paperprize #neuroscience 🧠 🧠 🧠

Corcia et al. present real-world data on patients living with amyotrophic lateral sclerosis in France. Findings cover patient characteristics at onset, survival, and healthcare resource use and associated costs per disease stage. Full articles 👉 buff.ly/0y8sWpL

Schlenker et al. investigated the structural connectome in patients with post-COVID-condition, focusing on the basal ganglia and thalamus. They found altered connectivity of the putamen, which was associated with fatigue. Full article 👉 buff.ly/Anr1ANc #covid

Vardarajan et al. used whole genome sequencing to identify causal mutations in the PANK2 gene. A homozygous variant was present in most affected individuals. Haplotype analysis confirmed a founder effect and an African ancestral origin. Full article 👉 buff.ly/t5eCSKy

Vellieux et al. compile data about Lance–Adams syndrome to outline the full spectrum and deepen our understanding of this disorder. They provide new perspectives on the mechanistic underpinnings of Lance–Adams syndrome. Full article 👉 buff.ly/LxENsjj

Hernández et al. reported that genetic risk influences disease onset and sex-specific differences, highlighting the role of polygenic scores in shaping Parkinson’s disease presentation and clinical heterogeneity. Full article 👉 buff.ly/Gusp7OW #parkinsons

Menardi et al. used multimodal imaging data to model cognitive decline. While preserved some regions showed unexpected inverted patterns.This may reflect mismatches between tau buildup or compensatory brain folding mechanisms countering neurodegeneration. buff.ly/O8vEemz

Shi et al. reported histological, transcriptional and splicing alterations in the spinal cord of myotonic mice with lesions limited to muscles, providing new insights into the neuro-muscle interdependence and the neuropathy of myotonic dystrophy 👉 buff.ly/zLuzRXJ

Latypov et al. report that machine learning models can predict duration of surgical outcomes for chronic facial pain. Findings demonstrate that surgical success can be anticipated pre-operatively using patient-specific multimodal data. 👉 buff.ly/fWpoT8R

Tsagkaris, McClelland et al. report that in paediatric dystonia, regional patterns of brain glucose metabolism, measured with PET imaging, are related to neurophysiological measures of the functional integrity of motor and sensory neural pathways. 👉 buff.ly/2vnTZLR

Kukulka et al. report that pontocerebellar hypoplasia is often linked to mutations in TSEN54, RARS2, EXOSC3 and AMPD2. They propose a dyadic gene-based classification to better diagnostic clarity, and highlight research opportunities. buff.ly/ucRHJrr

Durcan et al. propose that loss of noradrenaline links to the pathologic progression of neurodegenerative diseases. Clinical trials are warranted to test noradrenergic therapies as potential disease-modifying treatments. buff.ly/8hysOz6 #neurodegeneration

Zhu et al. reported that patients with persistent progression independent of relapse activity had a higher risk of disability and transition to secondary progressive multiple sclerosis. However, some showed improvement. Full article 👉 buff.ly/eGuNogH #multiplesclerosis

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Brain
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The Lancet Neurology
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British Neuroscience Association
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