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Excited to share two papers from our lab published today @NatureCatalysis and @angew_chem on ion-pairing asymmetric DNA catalysis (rdcu.be/eNEfn) and site-selective RNA modification (onlinelibrary.wiley.com/doi/10.1002/an…), respectively @ChemNUS @ResearchFoS @NUSingapore
Atom-swapping in a saturated heterocycle? We report a photocatalytic transmutation strategy in @Nature that exchanges O within an oxetane for N, S, C & even dual atoms, simplifying access to a variety of non-aromatic cyclic pharmacophores & enabling late-stage editing of complex…
Deoxygenative Cyanofunctionalization of Aldehydes and Ketones Enabled by Electrochemical Reduction | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja… 👍
Delighted to share our recent work on the synthesis of bioisostere. pubs.acs.org/doi/10.1021/ac…
so delighted to share our recent work on bioisostere. onlinelibrary.wiley.com/doi/10.1002/an… @angew_chem
Regioselective Electrochemical Borylation of Oxygenated Allylic Electrophiles: Method Development and Synthetic Applications | ACS Central Science pubs.acs.org/doi/10.1021/ac… 👍 a beautiful paper！
Check out this review article on Fe-catalyzed radical functionalization of alkenes in @NatureSynthesis. Great collaboration with the @Gutierrez_Lab. @uclachem @ChemNUS #ironcatalysis nature.com/articles/s4416… Read here: rdcu.be/eD6dY
Our latest invited review article on directing group-free alkene 1,2-dialkylation reactions, in honor of @songlin_chem for the 2025 Tetrahedron Young Investigator Award. #tetrahedron @ELSchemistry @ChemNUS sciencedirect.com/science/articl…
Catalyst-Controlled Regiodivergent Oxidation of Unsymmetrical Diols | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…
Our latest work in @NatureChemistry using copper catalysis to promote difluorocarbene insertion into epoxides, allowing us to access an interesting but elusive class of α,α-difluoro-oxetane pharmacophores. @ChemNUS nature.com/articles/s4155…
Radically improved sugar chemistry cen.acs.org/synthesis/Radi… via @cenmag @ChemNUS @OxfordChemistry @RosFrankInst #glycotime
Thrilled to share our latest work in @Nature in collaboration with the Davis Group at @RosFrankInst & @OxfordChemistry. We developed a 'cap & glycosylate' strategy that directly transforms native sugars into glycosides & glycoproteins! @ChemNUS #glycotime nature.com/articles/s4158…
nature.com
Direct radical functionalization of native sugars
Nature - A radical-based method for functionalizing native sugars shows a way to remove typical protecting-group manipulations.
Listen to organic chemist Ming Joo Koh talk about how he is shrinking synthetic chemistry’s environmental footprint during Part 4 of the C&EN #Talented12 Virtual Symposium Sept. 19-21 Register today for FREE at go.acs.org/20o @cenmag #OrganicChemistry
Humbled to represent @NUSingapore as part of this year’s @cenmag Talented 12! Grateful to all the folks who nominated. Special thanks to my mentors, co-workers, collaborators, funders and research team who helped build our program over the years. @ChemNUS cen.acs.org/synthesis/cata…
Online now: Directing group-free approaches for three-component catalytic dicarbofunctionalization of unactivated alkenes dlvr.it/SQKJFw
Also in @ScienceMagazine this week, a clever EZ approach to chiral aldehyde deracemization via photochemical isomerization from Mouxin Huang, Long Zhang, Tianrun Pan and Sanzhong Luo science.org/doi/10.1126/sc…
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