dbswcw's profile picture. Assoc Prof @ National University of Singapore

Christoph Winkler

@dbswcw

Assoc Prof @ National University of Singapore

Christoph Winkler reposted

Genort für Geschlechtsbestimmung bei Wechselkröten identifiziert. Erst der 2. bekannte genetische Mechanismus für Geschlechtsdifferenzierung bei > 8600 #Amphibien|arten. Hilft #Forschung zu #Umweltgiften. @NatureComms mit @LeibnizIGB, @NUSingapore👉 igb-berlin.de/news/genort-fu…


Christoph Winkler reposted

Gene locus for sex determination in the European green toad identified. This is only the 2nd known genetic mechanism for sex differentiation > 8600 #amphibian species. Important for #research on #EndocrineDisruptors. @NatureComms @LeibnizIGB @NUSingapore 👉igb-berlin.de/en/news/gene-c…


How do toads know whether to become boys or girls? Thrilled to share that findings from a wonderful collaboration with Heiner Kuhl and Matthias Stoeck from Leibniz Institute in Berlin @LeibnizIGB have just been published. @NUSingapore nature.com/articles/s4146…


Christoph Winkler reposted

Great analysis by collaborators in medaka, paddlefish (Amanda Cass and Marcus Davis), xenopus, sharks and lampreys maps the presence of this intermediate fin across vertebrates. @dbswcw @Enrique1Amaya @JanStundl @BronnerMarianne @petecurr

CarneyTomJ's tweet image. Great analysis by collaborators in medaka, paddlefish (Amanda Cass and Marcus Davis), xenopus, sharks and lampreys maps the presence of this intermediate fin across vertebrates. @dbswcw  @Enrique1Amaya  @JanStundl  @BronnerMarianne  @petecurr

From tank to bedside: Our work on the medaka fish model identified a promising blood marker predicting osteoporosis risk in men.

NUS scientists have discovered that blood levels of the chemokine protein CXCL9 reliably predict the risk of osteoporotic hip fractures in Chinese men. asbmr.onlinelibrary.wiley.com/doi/full/10.10…

ResearchFoS's tweet image. NUS scientists have discovered that blood levels of the chemokine protein CXCL9 reliably predict the risk of osteoporotic hip fractures in Chinese men.
asbmr.onlinelibrary.wiley.com/doi/full/10.10…


Christoph Winkler reposted

A new study links a biomarker in blood to the risk of osteoporotic hip fracture in men. Read more in @medical_xpress, featuring research by Quang Tien Phan, @dbswcw & team published #OpenAccess in @ASBMR Journal of Bone and Mineral Research. ow.ly/62Wk50KrY5u


Our first human study based on findings in our medaka fish model - so exciting! CXCL9 predicts the risk of osteoporotic hip fracture in a prospective cohort of Chinese men – a matched case‐control study asbmr.onlinelibrary.wiley.com/doi/10.1002/jb…


CXCL9 predicts the risk of osteoporotic hip fracture in a prospective cohort of Chinese men – a matched case‐control study …ibrary-wiley-com.libproxy1.nus.edu.sg/doi/10.1002/jb…


Christoph Winkler reposted

Ageing and Neurodegeneration concurrent session at #IZFC2022! First presentation is by @KessenPatten talking about #ALS in #zebrafish. 🦓🐟 @InfoIzfs @inrsciences

ZebrafishNerd's tweet image. Ageing and Neurodegeneration concurrent session at #IZFC2022! First presentation is by @KessenPatten talking about #ALS in #zebrafish. 🦓🐟

@InfoIzfs @inrsciences

Christoph Winkler reposted

A non-disruptive and efficient knock-in approach allows fate tracing of resident osteoblast progenitors during repair of vertebral lesions in medaka A Research article from our Stem Cells and Development section by Wen Hui Tan and @dbswcw @NUSingapore journals.biologists.com/dev/article/14…

Dev_journal's tweet image. A non-disruptive and efficient knock-in approach allows fate tracing of resident osteoblast progenitors during repair of vertebral lesions in medaka

A Research article from our Stem Cells and Development section by Wen Hui Tan and @dbswcw  @NUSingapore 

journals.biologists.com/dev/article/14…

Transcriptome Profiling of Osteoblasts in a Medaka (Oryzias latipes) Osteoporosis Model Identifies Mmp13b as Crucial for Osteoclast Activation frontiersin.org/article/10.338…


Macrophages switch to an osteo‐modulatory profile upon Rankl induction in a medaka (Oryzias latipes) osteoporosis model asbmr.onlinelibrary.wiley.com/doi/abs/10.100…


Our newest paper is out. Congrats to Tien and Wen Hui! And thanks to all collaborators for their hard work and support. pnas.org/content/early/…


Christoph Winkler reposted

"Celsr1a is essential for tissue homeostasis and onset of aging phenotypes in the.." is the #1 paper on bioRxiv today in developmental biology. Congrats @khenke2012 @Harris_MatthewJ. See it at -> assert.pub/biorxiv/develo… and assert.pub/papers/714063. Please retweet.


Christoph Winkler reposted

After a lot of hard work I'm happy to share our work on hybridisation and the evolution of a new sex chromosome in swordtail fish! Out now in @NatureComms: nature.com/articles/s4146… - @unikonstanz @UU_University @Uni_WUE


Christoph Winkler reposted

#zebrafish are ideal tools for modeling many rare diseases. Come 2 #zdm10 to learn all about this great science if you missed @SMBurgessLab

@SMBurgessLab explaining the importance of zebra fish for rare disease research/genomics #RDDNIH

PatientWorthy's tweet image. @SMBurgessLab explaining the importance of zebra fish for rare disease research/genomics  #RDDNIH


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