Gresham Lab
@djjgresham
News from the Gresham lab @ NYU and beyond.
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Are you looking for a biology postdoc position in New York City? Come visit us for a one day minisymposium for postdoc applicants as part of the emerging scholars program! Please RT! as.nyu.edu/departments/bi…
Yeast folks, after a fun #TAGC24 meeting with yeast sessions, more fun to come with the 32nd International Conference on Yeast Genetics and Molecular Biology. It will take place in Paris from July 21 to 24, 2025. Save the dates!
Exciting work @Ying_Xie_ and @LiamHoltLab Congrats.
New @bioRxiv preprint! tinyurl.com/mr4yxsxb @Ying_Xie_ found that polysome collapse & mRNA condensation fluidizes the cytoplasm. This helps assembly of another membraneless stress organelle: Q-bodies! P-bodies and SGs tune the physical properties of the cytoplasm! RT plz!
New @bioRxiv preprint! tinyurl.com/mr4yxsxb @Ying_Xie_ found that polysome collapse & mRNA condensation fluidizes the cytoplasm. This helps assembly of another membraneless stress organelle: Q-bodies! P-bodies and SGs tune the physical properties of the cytoplasm! RT plz!
Its #TransposonThursday! Sharing our newest preprint on context dependent mechanisms by which cancer cells co-evolve with retrotransposons (LINE1 and SINEs) to mitigate viral mimicry. A #TeamScience effort led by our postdoc @sunsiyu1 @CompOncMSK 👇👇👇 biorxiv.org/content/10.110…
Our paper on the mysterious flip/flop inversion polymorphism in Saccharomyces species -- It's old but it's young! Congratulations Letal, and thanks @PLOSGenetics for efficient handling. journals.plos.org/plosgenetics/a…
Learn all about the NYU Biology PhD Program at our online Open House on Tuesday, October 11. We’re excited to tell you about the department, the PhD program, and the admissions process. as.nyu.edu/biology/events…
Guy ( @Imnotyourguybud ) posts the lab's 1st completely de novo preprint, a very nice story about how bacteria become immune to bacteriophage if you tickle them!
Mechanical compression induces persistent bacterial growth during bacteriophage predation biorxiv.org/cgi/content/sh… #bioRxiv
A fitting finale to @Grace_Avecilla PhD at #NYU. Publication in #PLOSBiology of her amazing research on the very day she departs for her next adventure. Neural networks enable efficient and accurate simulation-based inference of evolutionary parameters dx.plos.org/10.1371/journa…
Beautiful work. Congrats @ZivNaomi
My latest work setting up white-opaque switching in Candida albicans as a model for the molecular analysis of cell fate switching in eukaryotes, out now in @PLOSBiology plos.io/3MA2IbA , in this paper we:
"I know it can be really overwhelming figuring out who to be, and when. Who you are now and how to act in order to get where you want to go. I have some good news: it’s totally up to you. I also have some terrifying news: it’s totally up to you." - @taylorswift13
I find animations useful to teach metrics to undergrads. I believe it improves understanding to see what goes on. Here is a thread with my favorite GIFs, most of them are re-makes of stuff from #EconTwitter.
Excited to share our latest study of phased polyploid genomes providing deeper insight into the multiple origins of domesticated Saccharomyces cerevisiae beer yeasts in @CurrentBiology - @InstUnivFr @unistra @ERC_Research cell.com/current-biolog…
cell.com
Phased polyploid genomes provide deeper insight into the multiple origins of domesticated Sacchar...
Abou Saada et al. sequenced and phased the genomes of 35 beer-related S. cerevisiae genomes, providing insight into the genetic makeup of this polyphyletic population. They show that highly divergent...
How does variable expressivity arise at the genetic level? Here, we examine how many genetic polymorphisms collectively cause the same mutation to show a spectrum of effects, from lethal to benign, across genetically diverse individuals. @GeneticsGSA academic.oup.com/genetics/advan…
My lab is looking for a postdoc (possibly two). We are interested in evolution, ecology, cell physiology. We do experiments and theory/modeling. If you or somebody you know is interested and has an appropriate background, please reach out. Please RT. sklab.science/opportunities
Super cool
Have you ever seen budding yeast cells going to bed after a hard day's work? We have dev a method to track single cells from a culture throughout all its growth phases (fermentation (FP), diauxic shift (DS), respiration (RP) & stationary phase (SP)):👇🧵 elifesciences.org/articles/73186
Congratulations!
#Indigenous knowledge + #Yeast #genomics + Bioactivity-guided #metabolomics = Molecular insight into #ethnobotany Sweet collaboration of healers & scientists @Seeseei1 @djjgresham @Pdorrestein1 @GNPS_UCSD @darachm among others. pnas.org/content/118/45…
Enrique Rojas uses experiments, theory, and computation at @NYUniversity to understand mechanisms of microbial growth and survival. His research at @TheRojasLab is elevating the study of bacterial mechanics to a more sophisticated level. #PackardFellows #BiologicalSciences
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